2. Outlines
⢠Introduction
⢠Epidemiology
⢠Aetiology and distribution
⢠Normal spinal anatomy
⢠Common mechanism of injury
⢠Prehospital management
⢠Diagnosis of spinal injury
⢠Management and prognosis
⢠Common type of spinal fracture
3. Introduction
⢠Spinal injuries are devastating
⢠Spinal injury may be defined as injury to
the spinal column (bone column)/spinal
cord or both
⢠Improper management can have horrible
and permanent result
⢠Appropriate use of immobilization can
mean difference between a patient who
fully recovers and other spent whole life
paralyzed.
4. Epidemiology
⢠40 cases per million in US
⢠Most common cervical region(55%)
⢠Mortality rate 40-50%
⢠Between the ages 16-30. M:F=4:1
⢠Most frequent age is 19
⢠Current estimates are 250,000 - 400,000
individuals living with Spinal Cord Injury
or Spinal Dysfunction.
11. Spinal cord and Nerves
âŞ31 pairs of nerves
âŞmotor and sensory
both
âŞLigaments provide
support
âŞCord is nerve tissue
âŞExtend from foramen
magnum to the L1 and
end in the form of
conus medullaris
13. Spinal Column Injury
Bony spinal injuries may or may not beBony spinal injuries may or may not be
associated with spinal cord injuryassociated with spinal cord injury
These bony injuries include:These bony injuries include:
â Compression fracturesCompression fractures
â Comminuted fracturesComminuted fractures
â Subluxation (partial dislocation)Subluxation (partial dislocation)
Other injuries may include:Other injuries may include:
â Sprains- over-stretching or tearing ofSprains- over-stretching or tearing of
ligamentsligaments
â Strains- over-stretching or tearing ofStrains- over-stretching or tearing of
the musclesthe muscles
14. Hyperflexion
Whiplash injury:(C3-7)
ďźTraumatic injury to the soft tissue in the cervical region
ďźHyperflexion, hyperextention
ďźNo fractures or dislocations
ďźMost common automobile injury
ďźRecover 3-6 months
Hyperextension
ďś Atlanto-occipital dislocation:
ďź frequently results in prehospital cardiorespiratory arrest
ďź 3 times more common in children than adults
ďź Unstable
15. Hyper rotation
ďś Atlanto-Axial dislocation:
ďź Transverse ligament injury
ďź more common in children than
adults
ďź 1/3 of patients have deficit
ďź Unstable
16. Spinal Cord injury
⢠Cutting compression or stretching of spinal
cord
⢠Causing loss of distal function sensation or
motion
⢠Caused by:
-unstable or sharp bony fragment
pushing the cord
- Pressure from bone fragments orPressure from bone fragments or
swelling that interrupts the blood supply toswelling that interrupts the blood supply to
the cord causing ischemiathe cord causing ischemia
17. Spinal cord injury
âŞPrimary spinal cord injury
- cutting, compression or stretching of
spinal cord
âŞSecondary spinal cord injury
-occurs later due to swelling, ischemia or
movement of unstable bony fragments
18. Spinal Cord injury severity
âŞComplete
- less common
- loss of motor and sensory function
below the level of injury
âŞIncomplete
- some preservation of motor and sensory
function
19. Spinal cord injury without radiological
abnormality(SCIWORA)
⢠referred to spinal cord injury without
radiographic or CT evidence of fracture or
dislocation
⢠With advent of MRI, term has become
ambiguous
⢠"Spinal cord injury without neuroimaging
abnormality" more correct name
⢠Mostly in pediatric population (range: birth to 16
years old)
⢠Common in cervical and thoracic region
20. Spinal cord injury without radiological
abnormality(SCIWORA)
⢠Following findings on MRI have been recognized
as causing primary or secondary spinal cord
injury:
-Intervertebral disk rupture
-Spinal epidural hematoma
-Cord contusion
-Hematomyelia
⢠Prognosis of SCIWORA is actually better than
patients with spinal cord injury and radiologic
evidence of traumatic injury
21. Suspected Spinal Injury
⢠High speed crash
⢠Compression injury (diving, fall on buttock)
⢠Significant blunt trauma
⢠Very violent mechanism
⢠Unconscious
⢠Neurological deficit
⢠Spinal pain/tenderness
22. Pre-hospital management
⢠Protect spine at all times during the
management of patients with multiple
injuries
⢠Up to 5% of spinal injuries have a second
(possibly non adjacent) fracture elsewhere in
the spine
⪠Ideally, whole spine should be immobilized
in neutral position on a firm surface
26. Transportation of spinal cord-injured
patients
⢠Emergency Medical Systems (EMS)
⢠Paramedical staff
⢠Primary trauma center
⢠Spinal injury center
28. Diagnosis of Spinal injury: clinical
evaluation
⢠Inspection and palpation: occiput to coccyx
- tenderness
- gap or step
- edema and bruising
- spasm of associated muscle
29. Diagnosis of Spinal injury: clinical
evaluation
⢠Neurological Examination
- sensation
- motor function
- reflexes
- rectal examination
32. Neurological Examination: Rectal
⢠Tone: the presence of rectal tone in itself
does not indicate incomplete injury
⢠Sensation
⢠Voilition: a voluntary contraction of
sphincter or the presence of rectal
sensation supports the presence of a
communication between the lower spinal
cord and supraspinal centers
33. Neurological examination: Rectal
⢠Bulbocavernosus reflex
-refers to anal sphincter contraction in response to
squeezing the glans penis or tugging on the
Foley;
-reflex involves S-1, S-2, and S-3 nerve roots and
is spinal cord- mediated reflex arc
-absence of this reflex documents continuation of
spinal shock or spinal injury at the level of the
reflex arc itself.
34. Is the patient awake or
âunexaminableâ?
⢠Whatâs the difference ?
â Awake
⢠ask/answer question
⢠pain/tenderness
⢠motor/sensory exam
â Not awake
⢠you can ask (but they wonât answer)
⢠canât assess tenderness
⢠no motor/sensory exam
OW!
------
35. Neurologic assessment and grading
⢠American Spinal Injury Association grade
â Grade A â E
⢠American Spinal Injury Association score
â Motor score (total = 100 points)
⢠Key muscles : 10 muscles
â Sensory score (total = 112 points)
⢠Key sensory points : 28 dermatomes
41. Radiographic imaging
⢠Who needs an x- ray of the spine ?
ďź NEXUS -The National Emergency X- Radiograph
Utilization Study
â Prospective study to validate a rule for the decision to obtain
cervical spine x- ray in trauma patients
â Hoffman, N Engl J Med 2000; 343:94-99
ďź Canadian C-Spine rules
â Prospective study whereby patients were evaluated for 20
standardized clinical findings as a basis for formulating a
decision as to the need for subsequent cervical spine
radiography
â Stiell I. JAMA. 2001; 286:1841-1846
42. NEXUS
⢠NEXUS Criteria:
1. Absence of tenderness in the posterior
midline
2. Absence of a neurological deficit
3. Normal level of alertness (GCS score = 15)
4. No evidence of intoxication (drugs or
alcohol)
5. No distracting injury/pain
43. NEXUS
⢠Patient who fulfilled all 5 of the criteria
were considered low risk for C-spine
injury
ď No need C-spine X-ray
⢠For patients who sort of any of the 5
criteria
ď radiographic imaging was indicated
( AP, lateral and open mouth views)
44. The Canadian C-spine Rule for alert and stable trauma patients where cervical
spine injury is a concern.
The Canadian C-spine Rule for alert and stable trauma patients where cervical
spine injury is a concern.
⢠Any high-risk factor that mandates radiography?
⢠Age>65yrs or
⢠Dangerous mechanism or
⢠Paresthesia in extremities
Any low-risk factor that allows safe
assessment of range of motion?
⢠Simple rear-end MVC, or
⢠Sitting position in ER, or
⢠Ambulatory at any time, or
⢠Delayed onset of neck pain, or
⢠Absence of midline C-spine tenderness
Able to actively rotate neck?
⢠45 degrees left and right
No Radiography
Radiography
NO
YES
ABLE
YES
NO
UNABLE
45. National Emergency X
Radiography Utilization Study
(NEXUS)
National Emergency X
Radiography Utilization Study
(NEXUS)
Both have:
⢠Excellent negative predictive value for
excluding patients identified as low risk
The Canadian C-spine rule
&
46. Clearance of Cervical Spine Injury in
Conscious, Symptomatic Patients
1. Radiological evaluation of the cervical spine
is indicated for all patients who do not meet
the criteria for clinical clearance as described
above
2. Imaging studies should be technically
adequate and interpreted by experienced
clinicians
47. Cervical Spine Imaging Options
â Plain films
⢠AP, lateral and open mouth view
â Optional: Oblique and Swimmerâs
â CT
⢠Better for occult fractures
â MRI
⢠Very good for spinal cord, soft tissue and ligamentous
injuries
â Flexion-Extension Plain Films
⢠to determine stability
49. Adequacy
⢠Must visualize entire C-spine
⢠A film that does not show
the upper border of T1 is
inadequate
⢠Caudal traction on the arms
may help
⢠If can not, get swimmerâs
view or CT
51. Alignment
⢠The anterior vertebral line,
posterior vertebral line, and
spinolaminar line should have
a smooth curve with no steps
or discontinuities
⢠Malalignment of the
posterior vertebral bodies is
more significant than that
anteriorly, which may be due
to rotation
⢠A step-off of >3.5mm is
significant anywhere
52. Lateral Cervical Spine X-Ray
⢠Anterior subluxation of one
vertebra on another indicates
facet dislocation
â < 50% of the width of a
vertebral body ď unilateral
facet dislocation
â > 50% ď bilateral facet
dislocation
55. Soft tissue
⢠Nasopharyngeal
space (C1)
â 10 mm (adult)
⢠Retropharyngeal
space (C2-C4)
â 5-7 mm
⢠Retrotracheal space
(C5-C7)
â 14 mm (children)
â 22 mm (adults)
56. AP C-spine Films
⢠Spinous processes should
line up
⢠Disc space should be
uniform
⢠Vertebral body height
should be uniform.
Check for oblique
fractures.
57. Open mouth view
⢠Adequacy: all of the: all of the
dens and lateraldens and lateral
borders of C1 & C2borders of C1 & C2
⢠Alignment: lateral: lateral
masses of C1 and C2masses of C1 and C2
⢠Bone: Inspect dens
for lucent fracture
lines
58. CT Scan
⢠Thin cut CT scan should be
used to evaluate abnormal,
suspicious or poorly
visualized areas on plain
film
⢠The combination of plain
film and directed CT scan
provides a false negative
rate of less than 0.1%
59. MRI
⢠Ideally all patients
with abnormal
neurological
examination should
be evaluated with
MRI scan
60. Management of SCI
⢠Primary Goal
â Prevent secondary injury
⢠Immobilization of the spine begins in the
initial assessment
â Treat the spine as a long bone
⢠Secure joint above and below
â Caution with âpartialâ spine splinting
61. Management of SCI
⢠Spinal motion restriction: immobilization devices
⢠ABCs
â Increase FiO2
â Assist ventilations as needed with c-spine control
â Indications for intubation :
⢠Acute respiratory failure
⢠GCS <9
⢠Increased RR with hypoxia
⢠PCO2 > 50
⢠VC < 10 mL/kg
â IV Access & fluids titrated to BP ~ 90-100 mmHg
62. Management of SCI
⢠Clinical assessment and neurological
examination
⢠Spinal Imaging and send laboratory
investigation
⢠GI intervention: put nasogastric tube to
prevent aspiration
⢠Pain Management
- Opiates and NSAIDs
63. Management of SCI
⢠Consider high dose methylprednisolone
â Controversial as recent evidence questions benefit
â Must be started < 8 hours of injury
â Do not use for penetrating trauma
â 30 mg/kg bolus over 15 minute
â Bolus followed by a 45-min pause
â Then infusion 5.4mg/kg IV for 23 hours
64. Neurogenic Shock
⢠Temporary loss of autonomic function of the cord at
the level of injury
â results from cervical or high thoracic injury
⢠Presentation
â Flaccid paralysis distal to injury site
â Loss of autonomic function
⢠hypotension
⢠vasodilatation
⢠loss of bladder and bowel control
⢠loss of thermoregulation
⢠warm, pink, dry below injury site
⢠bradycardia
66. Hemodynamic state in neurogenic
shock
⢠Unopposed parasympathetic outflow can lead to
dysrythmias and hypotension(most common
within 14 hours)
⢠Loss of sympathetic innervation to the heart (T1
through T4 cord levels) leaves the
parasympathetic cardiac innervation via the
vagus nerve unopposed, resulting in bradycardia,
or an absence of reflex tachycardia.
⢠Most common dysrythmia is bradycardia
67. Hemodynamic instability: intervention
⢠First line
volume resusciation ( 1-2 liter)
⢠Second line:
vasopressor (dopamine/norepinephrine) to
counter loss of sympathetic tone and
provide chronotropic support to the heart
68. Hemodynamics and cord perfusion
⢠Avoid hypotension
⢠Maintain MAP 85-90mmHg for first 7
days if possible
69. Bradycardia: intervention
⢠Prevention
-avoid vagal stimulation
- hyperventilate and hyperoxygenate
before suctioning
- premedicate patient with known
hypersensitivity to vagal stimuli
âŞSymptomatic bradycardia
atropine 0.5- 1.0 mg IV
70. Indication for Surgery
⢠Decompression of neural elements( spinal
cord and nerves)
⢠Stabilization of bony element( spine)
⢠Deformity correction
⢠Thoracolumbar spine fracture/dislocation
71. Prognosis of recovery
⢠Patient with complete cervical spine injuries that
remain within the first 24 hours of admission are
unlikely to regain significant ambulatory function
⢠Cervical injuries have a higher potential for
recovery than do thoracic or thoracolumbar
injuries
⢠Younger patient fare much better than older
⢠Intermedullary hemorrhage signifies a worse
neurological outcome
72. Jefferson Fracture
⢠Burst fracture of C1 ring
⢠cervical spine is subjected to an
axial load, as would occur from
a direct blow to the top of the
head
⢠Unstable fracture
⢠Need CT scan
73. Hangmanâs Fracture
⢠Hyperextension injury
⢠Bilateral fractures of
C2 pedicles
(white arrow)
⢠Anterior dislocation of
C2 vertebral body (red
arrow)
⢠Unstable
74. Odontoid Fractures
⢠Complex mechanism of injury
⢠Generally unstable
⢠Type 1 fracture through the tip
â Rare
⢠Type 2 fracture through the base
â Most common
⢠Type 3 fracture through the base and body of
axis
â Best prognosis
77. Burst Fracture
⢠Fracture of C3-C7 from
axial loading
⢠Spinal cord injury is
common from posterior
displacement of
fragments into the spinal
canal
⢠Unstable
78. Clay Shovelerâs Fracture
⢠Avulsion off the end of one
of the lower cervical spinous
processes
⢠C7>C6>T1
⢠Stable fracture
79. Flexion Teardrop Fracture
⢠Flexion injury causing a
fracture of the
anteroinferior portion of
the vertebral body
⢠Unstable because
usually associated with
posterior ligamentous
injury
80. Bilateral Facet Dislocation
⢠Flexion injury
⢠Subluxation of dislocated
vertebra of greater than ½
the AP diameter of the
vertebral body below it
⢠High incidence of spinal
cord injury
⢠Extremely unstable
Editor's Notes
Hyperflexion - Excessive/abnormal bending forward of the chin toward the chest. This is one mechanism seen when patients are ejected from moving vehicles
Hyperotation - Excessive/abnormal rotation. This may produce injuries in any area of the spine.
Bulbocavernosus Reflex - Discussion:   - bulbocaverosus reflex refers to anal sphincter contraction in response to squeezing the glans penis or tugging on the Foley;      - reflex involves S-1 , S-2 , and S-3 nerve roots and is spinal cord- mediated reflex arc;   - following spinal cord trauma, presence or absence of this reflex carries prognostic significance;      - in cases of cervical or thoracic cord injury, absence of this reflex documents continuation of spinal shock  or spinal injury at the level of                the reflex arc itself;         - period of spinal shock usually resolves w/ in 48 hours and return of bulbocavernosus reflex signals termination of spinal shock;      - note that spinal shock does not apply to lesions that occur below the cord, and therefore, low lumbar burst frx should not cause spinal                shock (and in this situation, the absence of the bulbocaveronsus reflex indicates that there is a cauda equina injury );         - persistent loss of the bulbocavernosus reflex may be a result of a conus medullaris injury (eg from an L1 burst frx ); - Prognositic Significance:   - complete absence of distal motor or sensory function or perirectal sensation, together with recovery of the bulbocavernosus reflex,           indicates a complete cord injury, and in such cases it is highly unlikely that significant neurologic function will ever return;      - therefore, if no motor or sensory recovery below the level of frx is present, pt has a complete spinal cord injury and no further distal                recovery of motor function can be expected;      - on other hand, any spared motor or sensory function below level of injury is considered incomplete spinal cord injury ;      - potential for recovery of incomplete lesion is determined by part of the cord most severely injured
Etiology: - direct anterior cord compression - flexion of cervical spine - thrombosis of anterior spinal atery Symptoms - complete paralysis of below the lesion with the loss of pain and touch sensation - preservation of propioception and vibratory function Prognosis : bad
Etiology - transverse hemisection of spinal cord -unilateral cord compression Symptoms -Ipsilateral spastic paresis, loss of proprioception and vibratory sensation, and contralateral loss of pain and temperature sensation Prognosis: good
Etilogy -Hyperextension injuries -Disruption of blood flow to the spinal cord -Cervical spinal stenosis Symptoms -Quadriparesisâgreater in the upper extremities than the lower extremities. Some loss of pain and temperature sensation, also greater in the upper extremities Prognosis: good
Neurogenic Shock Injury to the spinal cord at the level of the cervical or thoracic vertebrae causes peripheral sympathetic denervation. The loss of sympathetic arterial tone results in decreased systemic vascular resistance and blood pressure. Loss of sympathetic innervation to the heart (T1 through T4 cord levels) leaves the parasympathetic cardiac innervation via the vagus nerve unopposed, resulting in bradycardia, or an absence of reflex tachycardia. In general, patients with neurogenic shock are warm, peripherally vasodilated, and hypotensive with a relative bradycardia . Patients tend to tolerate hypotension relatively well, as peripheral oxygen delivery is presumably normal. Bradycardia is characteristic but not universal. Loss of sympathetic tone and subsequent inability to redirect blood from the periphery to the core may cause excessive heat loss and hypothermia.8 The diagnosis of neurogenic shock should be one of exclusion. Certain cluesâsuch as bradycardia and warm, dry skinâmay be evident, but hypotension in the trauma patient can never be presumed to be caused by neurogenic shock until other possible sources of hypotension have been excluded .9 A large percentage of patients will have significant concomitant injuries, with blood loss as the cause of their hypotension.9,10 A search for hemorrhage should be conducted before hypotension can be attributed solely to neurogenic shock. Treatment of Neurogenic Shock Loss of sympathetic innervation during neurogenic shock results in blood pooling in the distal circulation. Infusion of IV crystalloid will correct this relative hypovolemia. Adequate fluid resuscitation should be undertaken, with the aim of keeping the mean arterial blood pressure at 85 to 90 mm Hg for the first 7 days after acute spine injury.11 Though a bit arbitrary, it has been determined by collective clinical experience that this level of pressure provides adequate perfusion and minimizes the effects of secondary cord injury.12 The aggressive use of fluids in neurogenic shock should be performed with careful monitoring, as there is danger of excessive fluid replacement, with resultant heart failure and pulmonary edema.13 The placement of a pulmonary artery catheter and its resultant pressure measurements can be of tremendous benefit in helping to prevent excess fluid administration. If IV fluids are not adequate to maintain organ perfusion, positive inotropic pressor agents may be beneficial adjuncts to improve cardiac output and raise perfusion pressure.14 Optimal combinations and doses of these agents are variable and should be titrated to the patient's hemodynamic response. Bradycardia, when present, usually occurs within the first few hours or days after spinal cord injury because of a predominance of vagal tone to the heart. In cases of hemodynamically significant bradycardia, atropine may be needed. In rare instances, patients will have an atrioventricular conduction block, with significant bradycardia requiring a pacemaker
BCR: bulbocavernosus reflex Spinal Shock The syndrome neurogenic shock must be differentiated from spinal shock; the two terms have very different meanings and are not interchangeable. Spinal shock refers to the temporary loss or depression of spinal reflex activity that occurs below a complete or incomplete spinal cord injury. The lower the spinal cord injury, the more likely that all distal reflexes will be absent.15 Loss of neurologic function that occurs with spinal shock can cause an incomplete spinal cord injury to mimic a complete cord injury. Therefore, cord lesions cannot be deemed complete until spinal shock has resolved. The bulbocavernosus reflex is among the first to return as spinal shock resolves. The duration of spinal shock is variable; it generally persists for days to weeks.
Jefferson Fracture The Jefferson fracture is usually produced when the cervical spine is subjected to an axial load, as would occur from a direct blow to the top of the head. The occipital condyles are forced downward and produce a burst fracture by driving the lateral masses of C1 apart ( Figure 255-2 ). The Jefferson fracture produces outward displacement of the lateral masses on the open-mouth odontoid radiograph. A fracture through one lateral mass will cause unilateral displacement on the open-mouth view ( Figure 255-3 ). Spinal instability from the Jefferson fracture results from disruption of the transverse ligament and is likely if the lateral masses are significantly displaced. If displacement of both lateral masses (measured as offset from the superior corner of the C2 vertebral body on each side) is >7 mm when added together, rupture of the transverse ligament is likely, and the spine is unstable
Traumatic Spondylolisthesis of the Axis (Hangman's Fracture) The hangman's fracture describes a fracture of both pedicles of C2. The resulting instability allows the body of C2 to displace anteriorly on C3 ( Figure 255-7 ). This fracture is caused by an extension mechanism and has acquired its colloquial name from its association with judicial hangings, where the noose knot is placed under the subject's chin and snaps the head backward as the rope becomes taut at the end of a fall. Suicidal hangings do not usually cause the extreme hyperextension seen in judicial hangings and are not associated with the hangman's fracture. The same fracture is seen in motor vehicle crashes and diving accidents, where sudden hyperextension forces are applied in deceleration. Owing to the large diameter of the spinal canal at the level of C2, even displacement of C2 on C3 may not cause neurologic injury, and patients may be neurologically intact.