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TUMOURS OF
OROPHARYNX

 DEPT OF OTORHINOLARYNGOLOGY
            JJM M C
          DAVANAGERE
BENIGN TUMOURS
 Papilloma: usually asymptomatic, surgical excision is the
    treatment of choice
   Haemangioma: may be capillary or cavernous.
    Treatment is diathermy coagulation or injection of
    sclerosing agents. Cryotherapy and laser coagulation is
    also effective
   Pleomorphic adenoma: mostly seen submucosally on
    the hard or soft palate. It is potentially malignant and
    should be excised totally
   Mucous cyst: usually seen in vallecula. Surgical excision
    is the treatment of choice in case of symptomatic cysts
   Lipoma
   fibroma
Pleomorphic adenoma
Papilloma
MALIGNANT TUMOURS
 Common sites of malignancy in
 oropharynx are:
Base of tongue
Tonsil and tonsillar fossa
Faucial palatine arch (soft palate and
 anterior pillar)
Posterior pharyngeal wall
MALIGNANT TUMOURS

 Gross appearance:
Superficially spreading
Exophytic
Ulcerative
Infiltrative
MALIGNANT TUMOURS
 Histological classification:
Squamous cell carcinoma: may be
 well/moderately/poorly differentiated
Lymphoepithelioma
Adenocarcinoma
Lymphomas: both hodgkin and non-
 hodgkin
TNM CLASSIFICATION
TREATMENT
 Depends upon the site and extent of the
  disease, patients general condition,
  experience of treating surgeon and
  facilities available
 Options of treatment are
Surgery alone
Radiation alone
Surgery+radiotherapy
Chemotherapy+surgery+radiotherapy
Palliative therapy
CARCINOMA OF BASE OF TONGUE
   (POSTERIOR 1/3RD OF TONGUE)
 Commonly seen in our country
 Patients usually presents with enlarged
  neck nodes
 Earlier symptoms are sore throat, feeling
  of lump in throat, discomfort on swallowing
 Late features include referred pain in ear,
  dysphagia, bleeding from mouth, change
  in quality of speech (hot potato voice)
CARCINOMA OF BASE OF TONGUE
    (POSTERIOR 1/3RD OF TONGUE)
 Spread:
Local: spread to rest of tongue
 musculature, epiglottis, pre - epiglottic
 space, tonsils, faucial pillars, hypopharynx
Lymphatic spread: 70% of cases show
 cervical metastasis either unilateral or
 bilateral at the time of initial consultation.
 Jugulo-digastric nodes are first to be
 involved
Distant metastasis: bones, liver, lung may
 be involved
CARCINOMA OF BASE OF TONGUE
    (POSTERIOR 1/3RD OF TONGUE
 Diagnosis:
Indirect laryngoscopy
Palpation under anesthesia
CT scan
FNAC of neck nodes
Biopsy
CARCINOMA OF BASE OF TONGUE
     (POSTERIOR 1/3RD OF TONGUE
 Treatment:
 Radiosensitive tumours such as
  Lymphoepithelioma are treated by radiotherapy
  to the primary and neck nodes
 T1, T2 squamous cell carcinoma with N0, N1
  neck  surgical excision with block dissection
  with post operative radiotherapy
 T3, T4  surgical excision with mandibular
  resection, neck dissection and post operative
  radiation
 T4 lesions with extension to anterior tongue and
  vallecula  extensive surgery with total
  glossectomy and laryngectomy in addition to the
  block dissection
CARCINOMA TONSIL AND
      TONSILLAR FOSSA

 Squamous cell carcinomas are most
  common
 Presents as an ulcerated lesion with
  necrotic base
 Lymphomas present as unilateral tonsillar
  enlargement and mimic Quinsy
CARCINOMA TONSIL
LYMPHOMA OF TONSIL
CARCINOMA TONSIL AND
       TONSILLAR FOSSA
 Spread:
Local: may spread to soft palate, pillars,
 base of tongue, pharyngeal wall,
 hypopharynx, parapharyngeal space,
 mandible, pterygoid muscles
Lymphatic: 50% patients have initial
 cervical node involvement at the time of
 presentation. jugulo-digastric nodes are
 first to be involved
Distant metastasis: seen in late cases
CARCINOMA TONSIL AND
       TONSILLAR FOSSA
 Clinical features: persistent throat pain,
  dysphagia, ear ache, neck swelling,
  trismus, fetor oris
 Diagnosis: palpation, biopsy
 Treatment:
Radiotherapy
Surgery: excision of tonsil in early lesions.
  Commando operation for larger lesions
Combined therapy
COMMANDO OPERATION


  (Combined oro - mandibular resection with
  reconstruction)
 It involves wide surgical excision of
  primary tumor with hemimandibulectomy
  and radical neck dissection
CARCINOMA OF PALATINE
              ARCH
 Soft palate, uvula, anterior tonsillar pillar
    comprise palatine arch
   Most common tumour type is squamous
    cell carcinoma
   May spread locally to contiguous
    structures or lymph nodes
   Patient presents with persistent throat
    pain, local pain, ear ache
   Treatment is irradiation or surgery
CARCINOMA OF POSTERIOR AND
       LATERAL PHARYNGEAL WALL
 Lesions remain asymptomatic for long
    time
   They may spread submucosally to
    adjoining areas such as tonsil, soft palate,
    tongue, nasopharynx, hypopharynx
   They may also involve parapharyngeal
    space and anterior spinal ligaments
   Bilateral nodal involvement is common
   Treatment is irradiation or surgery
PARAPHARYNGEAL TUMOURS

 Tumors of deep lobe of parotid
 Neurogenic tumors: neurilemmomas
 Chemodectoma: carotid body tumor,
  glomus vagale
 Lipoma
PARAPHARYNGEAL TUMOURS
Tumors of deep lobe of parotid

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Tumours of oropharynx

  • 1. TUMOURS OF OROPHARYNX DEPT OF OTORHINOLARYNGOLOGY JJM M C DAVANAGERE
  • 2. BENIGN TUMOURS  Papilloma: usually asymptomatic, surgical excision is the treatment of choice  Haemangioma: may be capillary or cavernous. Treatment is diathermy coagulation or injection of sclerosing agents. Cryotherapy and laser coagulation is also effective  Pleomorphic adenoma: mostly seen submucosally on the hard or soft palate. It is potentially malignant and should be excised totally  Mucous cyst: usually seen in vallecula. Surgical excision is the treatment of choice in case of symptomatic cysts  Lipoma  fibroma
  • 5. MALIGNANT TUMOURS  Common sites of malignancy in oropharynx are: Base of tongue Tonsil and tonsillar fossa Faucial palatine arch (soft palate and anterior pillar) Posterior pharyngeal wall
  • 6. MALIGNANT TUMOURS  Gross appearance: Superficially spreading Exophytic Ulcerative Infiltrative
  • 7. MALIGNANT TUMOURS  Histological classification: Squamous cell carcinoma: may be well/moderately/poorly differentiated Lymphoepithelioma Adenocarcinoma Lymphomas: both hodgkin and non- hodgkin
  • 9.
  • 10. TREATMENT  Depends upon the site and extent of the disease, patients general condition, experience of treating surgeon and facilities available  Options of treatment are Surgery alone Radiation alone Surgery+radiotherapy Chemotherapy+surgery+radiotherapy Palliative therapy
  • 11. CARCINOMA OF BASE OF TONGUE (POSTERIOR 1/3RD OF TONGUE)  Commonly seen in our country  Patients usually presents with enlarged neck nodes  Earlier symptoms are sore throat, feeling of lump in throat, discomfort on swallowing  Late features include referred pain in ear, dysphagia, bleeding from mouth, change in quality of speech (hot potato voice)
  • 12.
  • 13. CARCINOMA OF BASE OF TONGUE (POSTERIOR 1/3RD OF TONGUE)  Spread: Local: spread to rest of tongue musculature, epiglottis, pre - epiglottic space, tonsils, faucial pillars, hypopharynx Lymphatic spread: 70% of cases show cervical metastasis either unilateral or bilateral at the time of initial consultation. Jugulo-digastric nodes are first to be involved Distant metastasis: bones, liver, lung may be involved
  • 14. CARCINOMA OF BASE OF TONGUE (POSTERIOR 1/3RD OF TONGUE  Diagnosis: Indirect laryngoscopy Palpation under anesthesia CT scan FNAC of neck nodes Biopsy
  • 15. CARCINOMA OF BASE OF TONGUE (POSTERIOR 1/3RD OF TONGUE  Treatment:  Radiosensitive tumours such as Lymphoepithelioma are treated by radiotherapy to the primary and neck nodes  T1, T2 squamous cell carcinoma with N0, N1 neck  surgical excision with block dissection with post operative radiotherapy  T3, T4  surgical excision with mandibular resection, neck dissection and post operative radiation  T4 lesions with extension to anterior tongue and vallecula  extensive surgery with total glossectomy and laryngectomy in addition to the block dissection
  • 16. CARCINOMA TONSIL AND TONSILLAR FOSSA  Squamous cell carcinomas are most common  Presents as an ulcerated lesion with necrotic base  Lymphomas present as unilateral tonsillar enlargement and mimic Quinsy
  • 19. CARCINOMA TONSIL AND TONSILLAR FOSSA  Spread: Local: may spread to soft palate, pillars, base of tongue, pharyngeal wall, hypopharynx, parapharyngeal space, mandible, pterygoid muscles Lymphatic: 50% patients have initial cervical node involvement at the time of presentation. jugulo-digastric nodes are first to be involved Distant metastasis: seen in late cases
  • 20. CARCINOMA TONSIL AND TONSILLAR FOSSA  Clinical features: persistent throat pain, dysphagia, ear ache, neck swelling, trismus, fetor oris  Diagnosis: palpation, biopsy  Treatment: Radiotherapy Surgery: excision of tonsil in early lesions. Commando operation for larger lesions Combined therapy
  • 21. COMMANDO OPERATION (Combined oro - mandibular resection with reconstruction)  It involves wide surgical excision of primary tumor with hemimandibulectomy and radical neck dissection
  • 22. CARCINOMA OF PALATINE ARCH  Soft palate, uvula, anterior tonsillar pillar comprise palatine arch  Most common tumour type is squamous cell carcinoma  May spread locally to contiguous structures or lymph nodes  Patient presents with persistent throat pain, local pain, ear ache  Treatment is irradiation or surgery
  • 23. CARCINOMA OF POSTERIOR AND LATERAL PHARYNGEAL WALL  Lesions remain asymptomatic for long time  They may spread submucosally to adjoining areas such as tonsil, soft palate, tongue, nasopharynx, hypopharynx  They may also involve parapharyngeal space and anterior spinal ligaments  Bilateral nodal involvement is common  Treatment is irradiation or surgery
  • 24. PARAPHARYNGEAL TUMOURS  Tumors of deep lobe of parotid  Neurogenic tumors: neurilemmomas  Chemodectoma: carotid body tumor, glomus vagale  Lipoma
  • 26. Tumors of deep lobe of parotid