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MAGNESIUM SULFATE

DOSAGE                   INDICATIONS            CONTRAINDICATIONS SIDE EFFECTS                 NURSING
                                                                                               RESPONSIBILITIES
     (ADULTS)                For Acute              It is contraindicated   CNS:                   Reserve IV use
     Parenteral              nephritis               with allergy to         Weakness,              in eclampsia for
     nutrition: 8-24         (children)              magnesium               Dizziness,             immediate life
     mEq/day IV              to control              products;               fainting,              threatening
     Mild Magnesium          hypertension,           heartblock,             sweating (PO)          situations.
     Deficiency: I g         For                     myocardial damage,      CV:                    Give IM route
     IM or IV q 6 hr         Hypomagnesemia          abdominal pain,         Palpitations           for deep IM
     for 4 doses )32.5       (replacement            nausea, vomiting or     GI: Excessive          injection of
     mEq/24 hr               therapy)                other symptoms of       bowel activity,        undiluted (50%)
     Severe                  For                     appendicitis; acute     Perianal               sol’n for adults;
     Hypomagnesemi           Preeclampsia/           surgical abdomen,       irritations.           dilute to a 20%
     a: Up to 2              eclampsia               fecal impaction,        Metabolic:             sol’n for
     mEq/kg IM               short-term              intestinal and          Hypermagnese           children.
     within 4 hr o 5 g       treatment for           biliary duct            mia and                Monitor serum
     (40 mEq)/1000           constipation.           obstruction,            toxicity in            magnesium
     mL D5W IV               Evacuation of the       Hepatitis.              patients with          levels during
     infused over 3          colon for rectal       Do not give during      renal failure.         parenteral
     hr.                     and bowel exams         2 hr preceding                                 therapy.
                                                     delivery because of                            Monitor knee-
                             To correct or
IM                                                   the risk of                                    jerk reflex
                             prevent
     Toxemia,                                        magnesium toxicity                             Do not give
                             hypomagnesemia
     eclampsia,                                      to the neonate                                 magnesium
                             Treatment of
     nephritis: 4-5 g                               Use cautiously with                            sulfate to
                             Atypical
     of a 50 solution                                renal imsufficiency                            patient with
                             ventricular
     of 4 hr as needed                          --                                                  abdominal pain,
                             arrhythmias(Tors
IV                           ades de pointes)                                                       nausea and
     1-4 g of 10-20%         Adjunctive                                                             vomiting
     solution. Do not        therapy for the                                                        Monitor bowel
     exceed                  treatment of acute                                                     function, If
1.5mL/min of a       MI                 diarrhea and
     10% solution. Or     Inhibition of      and cramping
     4-5 g of a 250       premature labor    occur,
     mL of 5%             Adjunct            discontinue
     dextrose. Do not     treatment of       usage.
     exceed               exacerbations of
     3mL/minute           acute asthma.
PO
     Laxative: 10-15
     g PO Epsom salt
     in glass of water

 (PEDIATRICS)

     Parenteral
     nutrition(infants)
     : 2-10 mEq/day
     IV.
     Antiepileptic:
     20-40 mg/kg in a
     20%
     solution,IM,
     Repeat as
     needed.
     Laxative: 5-10 g
     PO Epsom salt in
     a glass of water

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Drug study of magnesium sulfate

  • 1. MAGNESIUM SULFATE DOSAGE INDICATIONS CONTRAINDICATIONS SIDE EFFECTS NURSING RESPONSIBILITIES (ADULTS) For Acute  It is contraindicated CNS: Reserve IV use Parenteral nephritis with allergy to Weakness, in eclampsia for nutrition: 8-24 (children) magnesium Dizziness, immediate life mEq/day IV to control products; fainting, threatening Mild Magnesium hypertension, heartblock, sweating (PO) situations. Deficiency: I g For myocardial damage, CV: Give IM route IM or IV q 6 hr Hypomagnesemia abdominal pain, Palpitations for deep IM for 4 doses )32.5 (replacement nausea, vomiting or GI: Excessive injection of mEq/24 hr therapy) other symptoms of bowel activity, undiluted (50%) Severe For appendicitis; acute Perianal sol’n for adults; Hypomagnesemi Preeclampsia/ surgical abdomen, irritations. dilute to a 20% a: Up to 2 eclampsia fecal impaction, Metabolic: sol’n for mEq/kg IM short-term intestinal and Hypermagnese children. within 4 hr o 5 g treatment for biliary duct mia and Monitor serum (40 mEq)/1000 constipation. obstruction, toxicity in magnesium mL D5W IV Evacuation of the Hepatitis. patients with levels during infused over 3 colon for rectal  Do not give during renal failure. parenteral hr. and bowel exams 2 hr preceding therapy. delivery because of Monitor knee- To correct or IM the risk of jerk reflex prevent Toxemia, magnesium toxicity Do not give hypomagnesemia eclampsia, to the neonate magnesium Treatment of nephritis: 4-5 g  Use cautiously with sulfate to Atypical of a 50 solution renal imsufficiency patient with ventricular of 4 hr as needed -- abdominal pain, arrhythmias(Tors IV ades de pointes) nausea and 1-4 g of 10-20% Adjunctive vomiting solution. Do not therapy for the Monitor bowel exceed treatment of acute function, If
  • 2. 1.5mL/min of a MI diarrhea and 10% solution. Or Inhibition of and cramping 4-5 g of a 250 premature labor occur, mL of 5% Adjunct discontinue dextrose. Do not treatment of usage. exceed exacerbations of 3mL/minute acute asthma. PO Laxative: 10-15 g PO Epsom salt in glass of water (PEDIATRICS) Parenteral nutrition(infants) : 2-10 mEq/day IV. Antiepileptic: 20-40 mg/kg in a 20% solution,IM, Repeat as needed. Laxative: 5-10 g PO Epsom salt in a glass of water