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Radiosurgery: Overview R. Rick Bhasin, MD Department of Neurosurgery University of Florida
Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Definitions ,[object Object],[object Object]
History ,[object Object],[object Object],[object Object]
More History ,[object Object]
How does radiation work? ,[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Proton Therapy
Proton Therapy ,[object Object],[object Object]
Bragg Peak Effect While rapidly traveling through tissue, high-energy proton beams lose energy. As this energy is lost, the likelihood of the particle interacting with the tissue increases. This leads to deposition of most of the energy within a discrete band of spatial depth measuring roughly 12-20 mm.
Proton Beam Centers in the USA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Proton Therapy
Proton Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Gamma Knife
Development of the  Gamma Knife ,[object Object],[object Object],[object Object],[object Object]
Development of the  Gamma Knife ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Linear Accelerator Radiosurgery
History of LINAC Radiosurgery ,[object Object],[object Object],[object Object],[object Object]
History of LINAC Radiosurgery ,[object Object],[object Object],[object Object],[object Object],[object Object]
How LINAC Radiosurgery Works ,[object Object],Reduced error to within 2/10 mm
How LINAC Radiosurgery Works ,[object Object]
How LINAC Radiosurgery Works ,[object Object]
How LINAC Radiosurgery Works
[object Object]
[object Object],Frame-based intracranial positioning
Frameless intracranial positioning Used for fractionated radiotherapy
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Trilogy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intensity Modulated Radiotherapy (IMRT) ,[object Object],[object Object]
UF Radiosurgery Treatment Paradigm ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
How to place a headring ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dose Planning ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dose Falloff Curve
What do we treat with radiosurgery? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Radiation Doses Prescribed ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Brain Metastasis ,[object Object],[object Object],[object Object],[object Object],[object Object],Ulm et al, Neurosurgery 55: 1076-1085, 2004
 
AVM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Bradshaw et al, Neurosurgery 52:296-308,2003
 
Vestibular Schwannoma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Foote et al, J Neurosurg 95:440-449, 2001
 
Meningioma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Friedman et al, J Neurosrg 103:206-209, 2005
Glioblastoma Multiforme ,[object Object],[object Object],[object Object],[object Object]
Glioblastoma Multiforme ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Ulm et al, Neurosurgery 57:512-517, 2005
 
Spinal Radiosurgery ,[object Object],[object Object],[object Object],[object Object]
 
 
Cyberknife Outcomes ,[object Object],[object Object],[object Object],[object Object],[object Object]
Spinal Radiosurgery with Trilogy ,[object Object],[object Object]
Trigeminal Neuralgia ,[object Object],[object Object],[object Object],[object Object],Mehta et al, Neurosurgery: 57:1193-2000, 2005 .

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Radiosurgery Revised