Autism sprecturm disorder

Gayani  Liyanage (MBBS-Doctor)
Gayani Liyanage (MBBS-Doctor) Doctor -MBBS à Gayani Liyanage (MBBS-Doctor)
Gayani Liyanage -8D1
Outline
• What is autism ?
• Classification system
• Autistic spectrum disorder
• Diagnosis
• Treatment
• Challenges in Srilanka
What is Autism ?
Early childhood is a time of rapid brain growth and development.
However certain genetic and environment factors may cause brain
development delay.
These may cause communication difficulties ,social behavioral
challenges which may manifest in spectrum of disorder known as
autism .
Autism is …..
The characteristic type of abnormal functions in all the 3 areas of ,
 Social interaction
 Communication
 Restricted ,stereotyped repetitive behavior
(DSM-IV )
It is most pervasive development disorder.
Symptoms are typically recognized between one and two years of
age.(before 3 year )
Common in male than female 4:1 ratio .
Fist describe by psychiatrist “Leo Kanner” in 1943 in the US.
Leo Kanner was an Austrian-American psychiatrist, physician, and
social activist best known for his work related to autism. Before
working at the Henry Phipps Psychiatric Clinic at Johns Hopkins
Hospital in Baltimore, Maryland, Kanner practiced as a physician
in Germany and in South Dakota. In 1943, Kanner published his
landmark paper, "Autistic Disturbances of Affective Contact,"
describing 11 children who were highly intelligent but displayed
"a powerful desire for aloneness" and "an obsessive insistence on
persistent sameness.
According to world health organization by year 2020 children with
neurodevelopment disorder will raise by over 50% internationally .
Study in USA review 1 in 68 children affected by autism .
In Srilanka according to study conducted in urban Colombo 1 in 93
children are born with autism .
Classification system
There are 5 diagnostic categories
 Autistic disorder
 Asperger‘s syndrome
 Rett’s syndrome
 Childhood disintegrative disorder
 Pervasive developmental disorder not otherwise specified
(Atypical autism)
(DSM-IV,ICD-10)
The word Autisitic Spectrum Disorder ( ASD ) is widely used to describe
all of the condition .
Autistic disorder
Characters /Symptoms
1) Social deficits
 Reduced eye contact
 Unusual facial expression
 Lack of gesture
 Lack of empathy
 Few peer relationship
 Does not respond to affection
 Poor understanding about others feelings
 May not value the company of their parents
02) Communication deficit
 Speech may completely absent- 30%
 Common abnormalities in speech include
• Repetition of speech
• Unusual pitch ,stress ,rhythm
• Pronoun reversal
 Difficulty in two way conversation
03) Restricted repetitive interests and behavior
 Strange attachment to unusual objectives
 Spend majority of time with them and rejecting other toys
 Stereotypies – Hand flapping or head rolling
 Routines of behavior and inevitable show restriction to change
Asperger‘s syndrome
• Children with Asperger’s has characteristic impairment in social
interaction and repetitive behaviors or restricted interest that are
seen in autism but they have normal speech and intellectual abilities .
• Doesn’t become obvious until around 4-8 years (cause social
interaction and behaviors become relevant around this age )
• They have unusual deep interest in one particular topic and perform
at a high level in one particular activity
• Mood disorder and anxiety disorder seen in 65% od Asperger’s by
adulthood
• Majority of them attend main stream school with extra classroom
support but may be subjected to bulling due to their social
eccentricity
Rett’s syndrome
• Development disorder of the female and shows many characteristic
features of autism
• Cause due to mutation in MECP-2 gene on x-chromosome
• Develop in 6-18 month
• They loss speech ,motor skill , head growth, purposeful hand
movement
• Presented with physical problems (80%) ,constipation ,poor growth
,scoliosis ,cardiac and motor problems
• Average life expectancy 30 years
Childhood disintegrative disorder
• Shows normal development over first 2 years followed by marked
regression and loss of skill in multiple areas of development over few
month
• Present with difficulty in social skill ,communicating skill and
repetitive restricted interest and behavior
• Majority have sever form of epilepsy
• Functioning remain extremely low and individual never independent
Pervasive developmental disorder not otherwise
specified (Atypical autism)
• Children who do not quite meet the diagnostic criteria for a specific
neurodevelopment disorder but shows many of characteristic typical
of them
Diagnosis
Currently there is no specific medical test or diagnostic method to
identify autism.
Hence diagnosis is made on clinical observation and evaluation
involving multi disciplinary team including,
• Child psychiatrist
• Pediatrician
• Neurologist
• Phycologist
• Speech and language therapist
• Occupational therapist
From the birth differences or delay of
• child communication
• Social interaction
• Behavioral differences
Could be the primary observation in identification autism.
Ex: not response to stimuli such as smiling ,speech, facial expression ,cry
while holding, poor eye contact, over or under stimulation to sound.
Usually first notice by parents.
These development changes can be observed 1-2 years of their life .some of
them such as different social interaction may manifest lateron.
Treatment (General, biological ,psychological)
General
Treatment for children with autism require great responsibility and
care.
Treatment done by multidisciplinary team, not only medical team but
the involvement of parents ,family, teachers, different institute is
needed to help children with this condition .
To prevent the condition public awareness is important ,cause early
identification of condition minimize the effect of disease and treatment
give rise to good result.
These children’s communication skill, play skill , physical activities
social interactions and language skill play a important roll and daily and
regular interaction of these children with other children in educational
and other activities result better outcome .
So under general treatment option basically care about the children’s
• Psychoeducation
• Appropriate educational settings
• Psychiatric and physical co-morbidities
• Parental training
Biological
• Atypical antipsychotic (risperidone)- effective in reducing aggression ,
irritability, anxiety, stereotypies .
• Stimulants or Atomoxetine – effective in children with comorbid
ADHD (Attention Difficulties and Hyperactive Disorders)
• SSRI-reduce repetitive or obsessive behaviors
Psychological treatment
Behavioural training programmes
Aim is to reduce antisocial or troublesome behaviours
Ex-
 Speech and language therapy
 Social skill training
 Behavioural modification programmes
Course and prognosis
• 2/3 acquired some useful speech.
• Serious impairment usually remain.
• Abnormal behavior continue in to adulthood but become less social
impairing with time.
• Only about 10-20 % of children are able to attend a main stream
school (with normal IQ)
Challenges in Srilanka
 General Medical Officers (GMOs) in Sri Lanka, who are often the first
point of contact for families, may not be aware of the characteristics
of ASD and may be unsure how to advice parents or may dismiss their
concerns regarding their children. Therefore, families that are able. to
afford, seek help to obtain a diagnosis elsewhere, spending valuable
time and financial resources to travel to other more developed
countries.
Very few schools accepted children with ASD even the school did
that accept limited number per year.
Lack of adult service and employment opportunities.
There is a general lack of awareness among Sri Lankan society
regarding people with disabilities, especially those with ASD. There is
deep-seated stigma associated with disability in this country. This
stigma often makes people unwilling to even admit they have a family
member with a disability. Children and adults with ASD may not be
taken out in public for fear of embarrassment and shame from
society.
Thank you !
1 sur 26

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Autism sprecturm disorder

  • 2. Outline • What is autism ? • Classification system • Autistic spectrum disorder • Diagnosis • Treatment • Challenges in Srilanka
  • 3. What is Autism ? Early childhood is a time of rapid brain growth and development. However certain genetic and environment factors may cause brain development delay. These may cause communication difficulties ,social behavioral challenges which may manifest in spectrum of disorder known as autism .
  • 4. Autism is ….. The characteristic type of abnormal functions in all the 3 areas of ,  Social interaction  Communication  Restricted ,stereotyped repetitive behavior (DSM-IV ) It is most pervasive development disorder. Symptoms are typically recognized between one and two years of age.(before 3 year ) Common in male than female 4:1 ratio .
  • 5. Fist describe by psychiatrist “Leo Kanner” in 1943 in the US. Leo Kanner was an Austrian-American psychiatrist, physician, and social activist best known for his work related to autism. Before working at the Henry Phipps Psychiatric Clinic at Johns Hopkins Hospital in Baltimore, Maryland, Kanner practiced as a physician in Germany and in South Dakota. In 1943, Kanner published his landmark paper, "Autistic Disturbances of Affective Contact," describing 11 children who were highly intelligent but displayed "a powerful desire for aloneness" and "an obsessive insistence on persistent sameness.
  • 6. According to world health organization by year 2020 children with neurodevelopment disorder will raise by over 50% internationally . Study in USA review 1 in 68 children affected by autism . In Srilanka according to study conducted in urban Colombo 1 in 93 children are born with autism .
  • 7. Classification system There are 5 diagnostic categories  Autistic disorder  Asperger‘s syndrome  Rett’s syndrome  Childhood disintegrative disorder  Pervasive developmental disorder not otherwise specified (Atypical autism) (DSM-IV,ICD-10)
  • 8. The word Autisitic Spectrum Disorder ( ASD ) is widely used to describe all of the condition .
  • 9. Autistic disorder Characters /Symptoms 1) Social deficits  Reduced eye contact  Unusual facial expression  Lack of gesture  Lack of empathy  Few peer relationship  Does not respond to affection
  • 10.  Poor understanding about others feelings  May not value the company of their parents 02) Communication deficit  Speech may completely absent- 30%  Common abnormalities in speech include • Repetition of speech • Unusual pitch ,stress ,rhythm • Pronoun reversal  Difficulty in two way conversation
  • 11. 03) Restricted repetitive interests and behavior  Strange attachment to unusual objectives  Spend majority of time with them and rejecting other toys  Stereotypies – Hand flapping or head rolling  Routines of behavior and inevitable show restriction to change
  • 12. Asperger‘s syndrome • Children with Asperger’s has characteristic impairment in social interaction and repetitive behaviors or restricted interest that are seen in autism but they have normal speech and intellectual abilities . • Doesn’t become obvious until around 4-8 years (cause social interaction and behaviors become relevant around this age ) • They have unusual deep interest in one particular topic and perform at a high level in one particular activity
  • 13. • Mood disorder and anxiety disorder seen in 65% od Asperger’s by adulthood • Majority of them attend main stream school with extra classroom support but may be subjected to bulling due to their social eccentricity
  • 14. Rett’s syndrome • Development disorder of the female and shows many characteristic features of autism • Cause due to mutation in MECP-2 gene on x-chromosome • Develop in 6-18 month • They loss speech ,motor skill , head growth, purposeful hand movement • Presented with physical problems (80%) ,constipation ,poor growth ,scoliosis ,cardiac and motor problems • Average life expectancy 30 years
  • 15. Childhood disintegrative disorder • Shows normal development over first 2 years followed by marked regression and loss of skill in multiple areas of development over few month • Present with difficulty in social skill ,communicating skill and repetitive restricted interest and behavior • Majority have sever form of epilepsy • Functioning remain extremely low and individual never independent
  • 16. Pervasive developmental disorder not otherwise specified (Atypical autism) • Children who do not quite meet the diagnostic criteria for a specific neurodevelopment disorder but shows many of characteristic typical of them
  • 17. Diagnosis Currently there is no specific medical test or diagnostic method to identify autism. Hence diagnosis is made on clinical observation and evaluation involving multi disciplinary team including, • Child psychiatrist • Pediatrician • Neurologist • Phycologist • Speech and language therapist • Occupational therapist
  • 18. From the birth differences or delay of • child communication • Social interaction • Behavioral differences Could be the primary observation in identification autism. Ex: not response to stimuli such as smiling ,speech, facial expression ,cry while holding, poor eye contact, over or under stimulation to sound. Usually first notice by parents. These development changes can be observed 1-2 years of their life .some of them such as different social interaction may manifest lateron.
  • 19. Treatment (General, biological ,psychological) General Treatment for children with autism require great responsibility and care. Treatment done by multidisciplinary team, not only medical team but the involvement of parents ,family, teachers, different institute is needed to help children with this condition . To prevent the condition public awareness is important ,cause early identification of condition minimize the effect of disease and treatment give rise to good result.
  • 20. These children’s communication skill, play skill , physical activities social interactions and language skill play a important roll and daily and regular interaction of these children with other children in educational and other activities result better outcome . So under general treatment option basically care about the children’s • Psychoeducation • Appropriate educational settings • Psychiatric and physical co-morbidities • Parental training
  • 21. Biological • Atypical antipsychotic (risperidone)- effective in reducing aggression , irritability, anxiety, stereotypies . • Stimulants or Atomoxetine – effective in children with comorbid ADHD (Attention Difficulties and Hyperactive Disorders) • SSRI-reduce repetitive or obsessive behaviors
  • 22. Psychological treatment Behavioural training programmes Aim is to reduce antisocial or troublesome behaviours Ex-  Speech and language therapy  Social skill training  Behavioural modification programmes
  • 23. Course and prognosis • 2/3 acquired some useful speech. • Serious impairment usually remain. • Abnormal behavior continue in to adulthood but become less social impairing with time. • Only about 10-20 % of children are able to attend a main stream school (with normal IQ)
  • 24. Challenges in Srilanka  General Medical Officers (GMOs) in Sri Lanka, who are often the first point of contact for families, may not be aware of the characteristics of ASD and may be unsure how to advice parents or may dismiss their concerns regarding their children. Therefore, families that are able. to afford, seek help to obtain a diagnosis elsewhere, spending valuable time and financial resources to travel to other more developed countries. Very few schools accepted children with ASD even the school did that accept limited number per year. Lack of adult service and employment opportunities.
  • 25. There is a general lack of awareness among Sri Lankan society regarding people with disabilities, especially those with ASD. There is deep-seated stigma associated with disability in this country. This stigma often makes people unwilling to even admit they have a family member with a disability. Children and adults with ASD may not be taken out in public for fear of embarrassment and shame from society.