1. Genetic Diseases (Inherited Diseases) Zou Xiao-bing Department of Pediatrics 3rd Affiliated Hospital Sun Yat-sen University

4. Genetic diseases are increasing

22. Etiology of trisomy 21 Nondisjunction of chromosome #21 in meiosis

23. Etiology of translocation down syndrome During prophase of meiosis in a parent,there may be a transfer of a portion of one chromosome to another

24. Etiology of mosaic down syndrome death Develop to a mosaic down syndrome Nondisjunction of zygote during early stage

31. THANK YOU

32. 45, XO TURNER SYNDROME

33. 5p- back

39. Mental retardation and autism-like symptom Long face and big ears

44. back1 back2

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54. B1 B2