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Crispr

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Crispr

  1. 1. CRISPR Setting New Frontiers Cho Han, Chiang National Taiwan University 2016/5/15
  2. 2. Outline 1. Introduction to CRISPR and gene editing 2. Development of CRISPR: medicine, agriculture, environment 3. Pros and Cons of CRISPR 4. The future
  3. 3. What is CRISPR? Gene editing
  4. 4. Guide RNA Cas9 protein Components of CRISPR
  5. 5. CRISPR has Many applications
  6. 6. CRISPR in medicine HIV/AIDS
  7. 7. Other medical applications Muscular Dystrophy Cancer And Many more..
  8. 8. CRISPR in agriculture and environment Reduce hunger and poverty From: United Nations Environment Programme Improve nutrition, health, and rural livelihoods Facilitate social and environmental sustainability development More nutritious More resistant to climate and pests
  9. 9. Arabidopsis thaliana Tobacco plant CRISPR in agriculture and environment
  10. 10. Prospects are good, but…be cautious
  11. 11. Perspectives Many applications, limitless potential “With great power comes great responsibility”
  12. 12. References: 1. Development and Applications of CRISPR-Cas9 for Genome Engineering http://www.cell.com/cell/abstract/S0092-8674(14)00604-7 2. The CRISPR/Cas9 system for targeted genome editing http://www.clontech.com/US/Products/Genome_Editing/CRISPR_Cas9/Resources/About_CRISP R_Cas9 3. CRISPR IS COMING TO AGRICULTURE — WITH BIG IMPLICATIONS FOR FOOD, FARMERS, CONSUMERS AND NATURE http://ensia.com/voices/crispr-is-coming-to-agriculture-with-big-implications-for-food-farmers- consumers-and-nature/ 4. Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids http://www.nature.com/nm/journal/v21/n3/full/nm.3802.html 5. Agriculture: A new breed of edits http://www.nature.com/nature/journal/v528/n7580_supp/full/528S15a.html 6. CRISPR the disrupter http://www.nature.com/news/crispr-the-disruptor-1.17673
  13. 13. Thank you for listening. Questions?

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