Lupus is an autoimmune disease that can damage any part of the body, including joints, skin, kidneys, blood cells, heart and lungs. It affects women more than men and is characterized by periods of illness (flares) and wellness (remission). While the cause is unknown, genetics and environmental triggers likely play a role. Diagnosis involves reviewing a patient's medical history and symptoms and testing for autoantibodies and organ inflammation. Treatment aims to reduce symptoms and organ damage through medications like corticosteroids and hydroxychloroquine. Prognosis varies depending on organ involvement but early detection and treatment can lead to near normal life expectancy.