Gene Discovery and Microarray Analysis SETAC Meeting

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bioinformatics using GeneSpring GX10

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Expertise in Gene Discovery, Microarray Development and Bioinformatics SETAC 29 th Annual Meeting November 16th-20th Tampa, FL EcoArray, Inc. www.ecoarray.com

EcoArray Bioinformatics ,[object Object],[object Object],[object Object],[object Object],[object Object]

GeneSpring GX ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Principal components analysis (PCA) Quality control

Multiple pair-wise comparison Volcano plot ANOVA Venn Diagram

Basic/Advanced Statistics Now what? We can do the analysis for you . Advanced Basic ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],(optional) ,[object Object],[object Object],[object Object],[object Object]

Cluster Analysis ,[object Object],[object Object],[object Object],[object Object],Uncover interesting patterns

Prediction Model Goal: To build a robust model to predict known phenotypic samples from gene expression data. unknown sample Predict gene expression characteristics

Building a Prediction Model 1) Validate , 2) Train, 3) Classify ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

GeneSpring GX network builder 1) Right click on edge, Source of supporting literature (ie.PubMed) 2) Locate sentence(s),

Expertise in Gene Discovery, Microarray Development and Bioinformatics EcoArray, Inc. www.ecoarray.com Heather R. Hammers (Bioinformatician/Scientist) [email_address]

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