This is a powerpoint slide show having to do with 'How to Live - a Really Long Life - Maybe to 100+

1. How to LiveHow to Live
R e a l l y a L o n g L I f eR e a l l y a L o n g L I f e
May be 100+?May be 100+?
So Best to Start NowSo Best to Start Now

2. SIGNIFICANT HEALTH PRACTICESSIGNIFICANT HEALTH PRACTICES
PRACTICEPRACTICE RECOMMENDATIONRECOMMENDATION
1.1. SleepSleep. . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . 7-8 Hours7-8 Hours
2.2. Eating BreakfastEating Breakfast. . . . . . . . .. . . . . . . . . DailyDaily
3.3. Eating Between MealsEating Between Meals. .. . Rarely /NeverRarely /Never
4.4. Body WeightBody Weight. . . . . . . . . . . . .. . . . . . . . . . . . . Female: -5% to 9.99%Female: -5% to 9.99%
Male: -5% to 19.99%Male: -5% to 19.99%
5.5. Physical ActivityPhysical Activity. . . . . . . . .. . . . . . . . . Often - DailyOften - Daily
6.6. Drinking AlcoholDrinking Alcohol. . . . . . . . .. . . . . . . . . 0 - 20 - 2
7.7. SmokingSmoking. . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . NoneNone
1A-2

3. BELLOC & BRESLOW STUDYBELLOC & BRESLOW STUDY 0-2
4
3
5
6
7
Number of
Health Practices
20 25 30 35 40 45 50 55 60 65 70 75 80
HealthProblems
LessMore
1A-4

4. HEALTH PRACTICESHEALTH PRACTICES
MORTALITY
0 - 3 67 (45 + 22 Yrs)
No. Habits Age at Death
4 - 5 73 (45 + 28 Yrs)
6 - 7 78 (45 + 33 Yrs)
1A-3

5. Mortality 1974
100
63
45
0
20
40
60
80
100
120
0-3 4-5 6-7
Health Habits
RelativeRisk

6. How to Live to 100+How to Live to 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1BP >150 vs. 120 2.1

7. How to Live to 100+How to Live to 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1BP >150 vs. 120 2.1
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4

8. How to Live to Maybe to a 100+How to Live to Maybe to a 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1BP >150 vs. 120 2.1
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4
CigretsCigrets >>1 pk/day 2.51 pk/day 2.5

9. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1BP >150 vs. 120 2.1
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4
CigretsCigrets >>1 pk/day 2.51 pk/day 2.5
InactivityInactivity 2.02.0

10. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1BP >150 vs. 120 2.1

11. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 30BP >150 vs. 120 2.1 30

12. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 X 30 =BP >150 vs. 120 2.1 X 30 = 6363

13. How to Live to 100+How to Live to 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 X 30 =BP >150 vs. 120 2.1 X 30 = 6363
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 2525

14. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 X 30 =BP >150 vs. 120 2.1 X 30 = 6363
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 =X 25 = 6060

15. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 X 30 =BP >150 vs. 120 2.1 X 30 = 6363
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 =X 25 = 6060
CigretsCigrets >> 1 pk/day 2.5 301 pk/day 2.5 30

16. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 X 30 =BP >150 vs. 120 2.1 X 30 = 6363
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 =X 25 = 6060
CigretsCigrets >> 1 pk/day 2.5 X 30 =1 pk/day 2.5 X 30 = 7575

17. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 X 30 =BP >150 vs. 120 2.1 X 30 = 6363
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 =X 25 = 6060
CigretsCigrets >> 1 pk/day 2.5 X 30 =1 pk/day 2.5 X 30 = 7575
Inactivity 2.0 60Inactivity 2.0 60

18. How to Live to Maybe 100+How to Live to Maybe 100+
Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk
BP >150 vs. 120 2.1 X 30 =BP >150 vs. 120 2.1 X 30 = 6363
Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 =X 25 = 6060
CigretsCigrets >> 1 pk/day 2.5 X 30 =1 pk/day 2.5 X 30 = 7575
Inactivity 2.0 X 60 =Inactivity 2.0 X 60 = 120120

19. How to Live to Possibly 100+How to Live to Possibly 100+
byby
Calorie Restriction andCalorie Restriction and
Mind over MatterMind over Matter

20. How to Live to Maybe 100+How to Live to Maybe 100+
DESIGN OF FIRST STUDYDESIGN OF FIRST STUDY
 Group A: Ad LibitumGroup A: Ad Libitum
 Group B: 60% of Group AGroup B: 60% of Group A
from 6 weeks onfrom 6 weeks on

21. How to Live to Maybe 100+How to Live to Maybe 100+
DESIGN OF SECOND STUDYDESIGN OF SECOND STUDY
 Group 1: Ad LibitumGroup 1: Ad Libitum
 Group 2: 60% of Group 1 from 6 weeks onGroup 2: 60% of Group 1 from 6 weeks on
 Group 3: 60% 6 weeks to 6 months then Ad Lib.Group 3: 60% 6 weeks to 6 months then Ad Lib.
 Group 4: Ad Libitum to 6 months then 60%Group 4: Ad Libitum to 6 months then 60%
 Group 5: Same Calorie intake, 60% ProteinGroup 5: Same Calorie intake, 60% Protein

22. How to Live to Maybe 100+How to Live to Maybe 100+
Physiological Benefits ofPhysiological Benefits of
Calorie RestrictionCalorie Restriction
Serum CholesterolSerum Cholesterol
Mobilization of fatMobilization of fat
Loss of muscle massLoss of muscle mass
Loss of muscle functionLoss of muscle function

23. How to Live to Maybe 100+How to Live to Maybe 100+
Pathological Benefits ofPathological Benefits of
Calorie RestrictionCalorie Restriction
NephropathyNephropathy
MonthsMonths 66 1818 2424 3636
Group A None or slight SevereGroup A None or slight Severe LethalLethal
Group B None or slight - No progressionGroup B None or slight - No progression - None- None

24. How to Live to Maybe 100+How to Live to Maybe 100+
Pathological Benefits ofPathological Benefits of
Calorie RestrictionCalorie Restriction
CardiomyopathyCardiomyopathy
Grade 3Grade 3
Group AGroup A 21%21%
Group BGroup B 0%0%

25. How to Live to Perhaps 100+How to Live to Perhaps 100+
Pathological BenefitsPathological Benefits continuedcontinued
Testicular tumorsTesticular tumors
18 months18 months
Group AGroup A Nearly allNearly all
Group BGroup B Almost noneAlmost none

26. How to Live to Possibly 100+How to Live to Possibly 100+
Length of LifeLength of Life
MaximumMaximum AverageAverage
Group A 950 daysGroup A 950 days 2 years2 years
Group B 1430 days 3 yearsGroup B 1430 days 3 years

27. How to Live to Maybe 100+How to Live to Maybe 100+
Benefits of Calorie RestrictionBenefits of Calorie Restriction
Slows aging and age related changesSlows aging and age related changes
e.g. cholesterol levelse.g. cholesterol levels
mobilization of fatmobilization of fat
visionvision
jointsjoints
insulin sensitivityinsulin sensitivity

28. How to Live to Perhaps 100+How to Live to Perhaps 100+
Benefits of Calorie RestrictionBenefits of Calorie Restriction
 Preserves bone massPreserves bone mass
 Preserves muscle mass and muscle functionPreserves muscle mass and muscle function
 Preserves skin thicknessPreserves skin thickness
 Preserves immune functionPreserves immune function
 Preserves brain functionPreserves brain function

29. Newsweek Special Edition
Fall Winter 2001

30. How to live to About 100+How to live to About 100+
 How healthyHow healthy
are you?are you?
 Excellent healthExcellent health
 Average healthAverage health
 Poor healthPoor health

31. How to Live to Maybe 100+How to Live to Maybe 100+
AttendAttend
The Wellness ProgramThe Wellness Program
andand
Do everything he says!Do everything he says!