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Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65
www.ijera.com 60 | P a g e
Implementing Tumor Detection and Area Calculation in Mri
Image of Human Brain Using Image Processing Techniques
Sunil L. Bangare, Madhura Patil, Pallavi S. Bangare, Dr. S. T. Patil
Research Scholar, Dept. of Computer Science & Engineering, K. L. University, Vijaywada, A. P., India
Dept. of Information Technology, Sinhgad Academy of Engineering, Kondhwa-Bk, Pune, Maharashtra, India
Assistant Professor, Dept. of Information Technology, Sinhgad Academy of Engineering, Kondhwa-Bk, Pune,
Maharashtra, India
Professor, Dept. of Computer Engineering, Vishwakarma Institute of Technology, Pune, Maharashtra, India.
Abstract
This paper is based on the research on Human Brain Tumor which uses the MRI imaging technique to capture
the image. In this proposed work Brain Tumor area is calculated to define the Stage or level of seriousness of
the tumor. Image Processing techniques are used for the brain tumor area calculation and Neural Network
algorithms for the tumor position calculation. Also in the further advancement the classification of the tumor
based on few parameters is also expected. Proposed work is divided in to following Modules:
Module 1: Image Pre-Processing
Module 2: Feature Extraction, Segmentation using K-Means Algorithm and Fuzzy C-Means Algorithm
Module 3: Tumor Area calculation & Stage detection
Module 4: Classification and position calculation of tumor using Neural Network
Keywords: Magnetic Resonance Imaging (MRI), CT-Scan, Brain tumor, K-Means, Pre-Processing, Fuzzy C-
Means, Thresholding, Neural Network
I. INTRODUCTION
Medical Image processing is an important filed
of research as its results can be used for the
betterment of health issues. This proposed work deals
with the Brain tumor segmentation and its area
calculation along with its classification using Neural
Network. To capture the MRI image and CT scan are
the available techniques. This work is based on the
image MRI input image. CT Scan is having the
drawback of radiation so this work is based on only
MRI image. MRI technique is widely used in the
Hospitals for diagnosis of diseases etc [1].
Image processing is having the power to perform
a good research in this field of Medical Sciences.
II. MOTIVATION
J. Selvakumar et al have given in their work that
Tumor is due to the uncontrolled growth of the
tissues in any part of the body. The tumor can be at
Origin or it can be spread at another location. Brain
tumor affects CSF (Cerebral Spinal Fluid). It causes
for strokes. The physician gives the treatment for the
strokes rather than the treatment for tumor. So
detection of tumors important for that treatment [1].
In this work Initial and Critical stages of the tumor
will be identified along with its position and shape.
Neural Network and Image processing is used for the
implementing this proposed work.
III. EXISTING SYSTEM
J. Selvakumar et al have given in their work that
The existing method is based on the
1. Thresholding: This method was not including the
Spatial characteristics which are important for the
malignant tumor detection. Also bit map images from
0 to 255 gray scale values were not involved and the
tumor cells may were wrongly interpreted.
2. Region growing: This method is having problem
of Seed selection and dependency on User
interaction. It does not work for all types of images.
RESEARCH ARTICLE OPEN ACCESS
Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65
www.ijera.com 61 | P a g e
IV. PROPOSED SYSTEM
Fig.1: Proposed System
IV. MODULE DESCRIPTION
Module 1: Image Pre-Processing
Generally captured image is of poor quality so
Image pre processing is required for Noise filtering in
the image and also for sharpening the image. RGB to
grey conversion and Reshaping is also done in this
step. It includes median filter for noise removal.
Image Pre-processing step is useful before going for
the Segmentation of the image.
Module 2: Feature Extraction, Segmentation
using K-Means Algorithm and Fuzzy C-Means
Algorithm
The Feature extraction is extracting the cluster
which shows the group of the abnormal tissues. The
extracted cluster is given to the thresholding process
it applies binary mask over the entire image which
gives the output as dark pixel becomes darker and
white becomes whiter.In threshold coding, each
transform coefficient is compared with a threshold.
If (transform coefficient) < (threshold value) then the
value assign to them is 0. In this case the it is treated
as “Background” which will be neglected.
If (transform coefficient) > (threshold value)
then the value assign to them is 1.In this case the it is
treated as “Foreground” which will be highlighted.
Image segmentation is used to convert the image
in to more meaningful image. The main objective of
image segmentation is to extract various features of
the images that may merge or split in order to build
objects of interest on which analysis and
interpretations Performed. Image segmentation is the
process of partitioning an image into groups of pixels
that are identical with respect to some criterion. The
result of segmentation is the splitting up of the image
into connected areas. Thus, segment is concerned
with dividing an image into meaningful regions [2].
In this work the K-Means and Fuzzy C-Means
algorithms are used for the segmentation. Both these
algorithms are well known for the tumor
Segmentation.
K-Means Algorithm:
K-Means is mostly used method based on the
concept of Centroid.
The K-Means Algorithm Process:
Input MRI Image
Image Pre-Processing
Feature Extraction
Image Segmentation using:
1. K-Means Algorithm
2. Fuzzy C-Means Algorithm
Area Calculation & Stage
Detection
Classification using Neural
Network Algorithms
Position calculation using
proposed algorithm
Position calculation using
Neural Network algorithm
Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65
www.ijera.com 62 | P a g e
1. The dataset is partitioned into K clusters and the
data points are randomly assigned to the clusters
resulting in clusters that have roughly the same
number of data points.
2. For each data point:
a. Calculate the distance from the data point to
each cluster.
b. If the data point is closest to its own cluster,
leave it where it is. If the data point is not
closest to its own cluster, move it into the
closest cluster.
3. Repeat the above step until a complete pass
through all the data points results in no data
point moving from one cluster to another. At this
point the clusters are stable and the clustering
process ends.
4. The choice of initial partition can greatly affect
the final clusters that result, in terms of inter-
cluster and intracluster distances and cohesion
[1] [5].
Fig.2: Pre-Processing and K-Means Algorithm output
Fuzzy C-Means Algorithm
The output of the K-Means algorithm is used as
input to this Fuzzy C-Means algorithm. In Fuzzy C-
Means a value is given to the each pixel in image,
this value ranges from 0 to 1. Fuzzy clustering is
basically a multi valued fuzzy set can also be member
of other fuzzy sets in the same image.
Let X = {x1, x2, x3 ..., xn} be the set of data points
and V = {v1, v2, v3 ..., vc} be the set of centers [1] [6].
1. Randomly select ‘c’ cluster centers.
2. Calculate the fuzzy membership 'µij' using:
3. Compute the fuzzy centers 'vj'
using:
5. Repeat step 2) and 3) until the minimum 'J' value
is achieved or ||U (k+1)
- U (k)
|| < β. Where,
‘k’ is the iteration step.
‘β’ is the termination criterion between [0, 1].
‘U = (µij)n*c’ is the fuzzy membership matrix.
‘J’ is the objective function.
Fig.3: Fuzzy C-Means Algorithm output
Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65
www.ijera.com 63 | P a g e
Fig.4: Tumor area output
Module 4: Tumor Area calculation & Stage
detection
In this step the tumor area calculation using
binarization method is done. That is the image having
only two values either black (0) or white (1). Here
256x256 jpeg image is a maximum image size. The
binary image can be represented as a summation of
total number of white and black pixels [1].
Pixels = Width (W) x Height (H) = 256 X 256
f (1) = white pixel (digit 1)
f (0) = black pixel (digit 0)
no_of_white_pixel, P=∑∑[f(0)]
Where,
P = number of white pixels (width*height)
1 Pixel = 0.264 mm
The area calculation formula is
Size_of_tumor_is, S=[(√P)*0.264]mm2
Fig.5: Tumor Area calculation & Stage detection output
Extra Module:
In this work we have created an additional facility for the doctors or patients who are users of this project to
access the patient data like MRI image etc through „Hospital Management System‟.
Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65
www.ijera.com 64 | P a g e
Fig.6 Login for HMS
Fig.7 Screenshot of Dashboard required for HMS
V. Conclusion
In this research work K-Means and Fuzzy C-
Means are used effectively to calculate the area and
stage of brain tumor. Also these algorithms have
overcome the drawbacks of thresholding and region
growing algorithms. The output of the K-Means
algorithm is used as input for the Fuzzy C-Means
which leads to accuracy of edge of the tumor. This
work shows that the image processing can be used in
the Medical imaging field.
In the next manuscript the classification using
neural network will be provided.
References
[1] J. Selvakumar, A.Lakshmi, T. Arivoli,
“Brain Tumor Segmentation and Its Area
Calculation in Brain MR Images using K-
Mean Clustering and Fuzzy C-Mean
Algorithm”, IEEE-International Conference
On Advances In Engineering, Science And
Management (ICAESM -2012) March 30,
31, 2012, ISBN: 978-81-909042-2-3 ©2012
IEEE
[2] S. Valarmathy, R. Ramani, Dr. N.
Suthanthira Vanitha, “A Survey of Recent
Image Segmentation Techniques for MRI
Brain Images”, ISSN: 0976-8491 (Online),
IJCST Vol. 4, Iss ue 1, Jan - March 2013
[3] Dr.S.K.Bandhyopadhyay and Tuhin Utsab
Paul, “ Segmentation of Brain MRI Image –
A Review”, International Journal of
Advanced Research in Computer Science
and Software Engineering, Volume 2, Issue
3, March 2012 ISSN: 2277 128X
[4] M. M. Ahmed, D.B. Mohammad,
“Segmentation of Brain MR Images for
Tumor Extraction by Combining K-means
Clustering and Perona-Malik Anisotropic
Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com
ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65
www.ijera.com 65 | P a g e
Diffusion Model”, International Journal of
Image Processing (IJIP), Book: 2008
Volume 2, Issue 1, Publishing Date: 28-02 -
2008, Proceedings ISSN (Online): 1985-
2304.
[5] http://www.improvedoutcomes.com/docs/
WebSiteDocs/Clustering/K-Means_Cluste
ring_Overview.htm
[6] https://sites.google.com/site/dataclusteringa
lgorithms/fuzzy-c-means-clustering-algorith
m
[7] S. L. Bangare, P. S. Bangare, S. T. Patil, T.
V. Rao, “Various Image Segmentation
Techniques- focusing on Brain MRI Images
- A Review”, National Conference on Latest
Trends in Electronics & Telecomm.
(NCLTE-2013).

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Implementing Tumor Detection and Area Calculation in Mri Image of Human Brain Using Image Processing Techniques

  • 1. Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65 www.ijera.com 60 | P a g e Implementing Tumor Detection and Area Calculation in Mri Image of Human Brain Using Image Processing Techniques Sunil L. Bangare, Madhura Patil, Pallavi S. Bangare, Dr. S. T. Patil Research Scholar, Dept. of Computer Science & Engineering, K. L. University, Vijaywada, A. P., India Dept. of Information Technology, Sinhgad Academy of Engineering, Kondhwa-Bk, Pune, Maharashtra, India Assistant Professor, Dept. of Information Technology, Sinhgad Academy of Engineering, Kondhwa-Bk, Pune, Maharashtra, India Professor, Dept. of Computer Engineering, Vishwakarma Institute of Technology, Pune, Maharashtra, India. Abstract This paper is based on the research on Human Brain Tumor which uses the MRI imaging technique to capture the image. In this proposed work Brain Tumor area is calculated to define the Stage or level of seriousness of the tumor. Image Processing techniques are used for the brain tumor area calculation and Neural Network algorithms for the tumor position calculation. Also in the further advancement the classification of the tumor based on few parameters is also expected. Proposed work is divided in to following Modules: Module 1: Image Pre-Processing Module 2: Feature Extraction, Segmentation using K-Means Algorithm and Fuzzy C-Means Algorithm Module 3: Tumor Area calculation & Stage detection Module 4: Classification and position calculation of tumor using Neural Network Keywords: Magnetic Resonance Imaging (MRI), CT-Scan, Brain tumor, K-Means, Pre-Processing, Fuzzy C- Means, Thresholding, Neural Network I. INTRODUCTION Medical Image processing is an important filed of research as its results can be used for the betterment of health issues. This proposed work deals with the Brain tumor segmentation and its area calculation along with its classification using Neural Network. To capture the MRI image and CT scan are the available techniques. This work is based on the image MRI input image. CT Scan is having the drawback of radiation so this work is based on only MRI image. MRI technique is widely used in the Hospitals for diagnosis of diseases etc [1]. Image processing is having the power to perform a good research in this field of Medical Sciences. II. MOTIVATION J. Selvakumar et al have given in their work that Tumor is due to the uncontrolled growth of the tissues in any part of the body. The tumor can be at Origin or it can be spread at another location. Brain tumor affects CSF (Cerebral Spinal Fluid). It causes for strokes. The physician gives the treatment for the strokes rather than the treatment for tumor. So detection of tumors important for that treatment [1]. In this work Initial and Critical stages of the tumor will be identified along with its position and shape. Neural Network and Image processing is used for the implementing this proposed work. III. EXISTING SYSTEM J. Selvakumar et al have given in their work that The existing method is based on the 1. Thresholding: This method was not including the Spatial characteristics which are important for the malignant tumor detection. Also bit map images from 0 to 255 gray scale values were not involved and the tumor cells may were wrongly interpreted. 2. Region growing: This method is having problem of Seed selection and dependency on User interaction. It does not work for all types of images. RESEARCH ARTICLE OPEN ACCESS
  • 2. Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65 www.ijera.com 61 | P a g e IV. PROPOSED SYSTEM Fig.1: Proposed System IV. MODULE DESCRIPTION Module 1: Image Pre-Processing Generally captured image is of poor quality so Image pre processing is required for Noise filtering in the image and also for sharpening the image. RGB to grey conversion and Reshaping is also done in this step. It includes median filter for noise removal. Image Pre-processing step is useful before going for the Segmentation of the image. Module 2: Feature Extraction, Segmentation using K-Means Algorithm and Fuzzy C-Means Algorithm The Feature extraction is extracting the cluster which shows the group of the abnormal tissues. The extracted cluster is given to the thresholding process it applies binary mask over the entire image which gives the output as dark pixel becomes darker and white becomes whiter.In threshold coding, each transform coefficient is compared with a threshold. If (transform coefficient) < (threshold value) then the value assign to them is 0. In this case the it is treated as “Background” which will be neglected. If (transform coefficient) > (threshold value) then the value assign to them is 1.In this case the it is treated as “Foreground” which will be highlighted. Image segmentation is used to convert the image in to more meaningful image. The main objective of image segmentation is to extract various features of the images that may merge or split in order to build objects of interest on which analysis and interpretations Performed. Image segmentation is the process of partitioning an image into groups of pixels that are identical with respect to some criterion. The result of segmentation is the splitting up of the image into connected areas. Thus, segment is concerned with dividing an image into meaningful regions [2]. In this work the K-Means and Fuzzy C-Means algorithms are used for the segmentation. Both these algorithms are well known for the tumor Segmentation. K-Means Algorithm: K-Means is mostly used method based on the concept of Centroid. The K-Means Algorithm Process: Input MRI Image Image Pre-Processing Feature Extraction Image Segmentation using: 1. K-Means Algorithm 2. Fuzzy C-Means Algorithm Area Calculation & Stage Detection Classification using Neural Network Algorithms Position calculation using proposed algorithm Position calculation using Neural Network algorithm
  • 3. Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65 www.ijera.com 62 | P a g e 1. The dataset is partitioned into K clusters and the data points are randomly assigned to the clusters resulting in clusters that have roughly the same number of data points. 2. For each data point: a. Calculate the distance from the data point to each cluster. b. If the data point is closest to its own cluster, leave it where it is. If the data point is not closest to its own cluster, move it into the closest cluster. 3. Repeat the above step until a complete pass through all the data points results in no data point moving from one cluster to another. At this point the clusters are stable and the clustering process ends. 4. The choice of initial partition can greatly affect the final clusters that result, in terms of inter- cluster and intracluster distances and cohesion [1] [5]. Fig.2: Pre-Processing and K-Means Algorithm output Fuzzy C-Means Algorithm The output of the K-Means algorithm is used as input to this Fuzzy C-Means algorithm. In Fuzzy C- Means a value is given to the each pixel in image, this value ranges from 0 to 1. Fuzzy clustering is basically a multi valued fuzzy set can also be member of other fuzzy sets in the same image. Let X = {x1, x2, x3 ..., xn} be the set of data points and V = {v1, v2, v3 ..., vc} be the set of centers [1] [6]. 1. Randomly select ‘c’ cluster centers. 2. Calculate the fuzzy membership 'µij' using: 3. Compute the fuzzy centers 'vj' using: 5. Repeat step 2) and 3) until the minimum 'J' value is achieved or ||U (k+1) - U (k) || < β. Where, ‘k’ is the iteration step. ‘β’ is the termination criterion between [0, 1]. ‘U = (µij)n*c’ is the fuzzy membership matrix. ‘J’ is the objective function. Fig.3: Fuzzy C-Means Algorithm output
  • 4. Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65 www.ijera.com 63 | P a g e Fig.4: Tumor area output Module 4: Tumor Area calculation & Stage detection In this step the tumor area calculation using binarization method is done. That is the image having only two values either black (0) or white (1). Here 256x256 jpeg image is a maximum image size. The binary image can be represented as a summation of total number of white and black pixels [1]. Pixels = Width (W) x Height (H) = 256 X 256 f (1) = white pixel (digit 1) f (0) = black pixel (digit 0) no_of_white_pixel, P=∑∑[f(0)] Where, P = number of white pixels (width*height) 1 Pixel = 0.264 mm The area calculation formula is Size_of_tumor_is, S=[(√P)*0.264]mm2 Fig.5: Tumor Area calculation & Stage detection output Extra Module: In this work we have created an additional facility for the doctors or patients who are users of this project to access the patient data like MRI image etc through „Hospital Management System‟.
  • 5. Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65 www.ijera.com 64 | P a g e Fig.6 Login for HMS Fig.7 Screenshot of Dashboard required for HMS V. Conclusion In this research work K-Means and Fuzzy C- Means are used effectively to calculate the area and stage of brain tumor. Also these algorithms have overcome the drawbacks of thresholding and region growing algorithms. The output of the K-Means algorithm is used as input for the Fuzzy C-Means which leads to accuracy of edge of the tumor. This work shows that the image processing can be used in the Medical imaging field. In the next manuscript the classification using neural network will be provided. References [1] J. Selvakumar, A.Lakshmi, T. Arivoli, “Brain Tumor Segmentation and Its Area Calculation in Brain MR Images using K- Mean Clustering and Fuzzy C-Mean Algorithm”, IEEE-International Conference On Advances In Engineering, Science And Management (ICAESM -2012) March 30, 31, 2012, ISBN: 978-81-909042-2-3 ©2012 IEEE [2] S. Valarmathy, R. Ramani, Dr. N. Suthanthira Vanitha, “A Survey of Recent Image Segmentation Techniques for MRI Brain Images”, ISSN: 0976-8491 (Online), IJCST Vol. 4, Iss ue 1, Jan - March 2013 [3] Dr.S.K.Bandhyopadhyay and Tuhin Utsab Paul, “ Segmentation of Brain MRI Image – A Review”, International Journal of Advanced Research in Computer Science and Software Engineering, Volume 2, Issue 3, March 2012 ISSN: 2277 128X [4] M. M. Ahmed, D.B. Mohammad, “Segmentation of Brain MR Images for Tumor Extraction by Combining K-means Clustering and Perona-Malik Anisotropic
  • 6. Sunil L. Bangare et al. Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 5, Issue 4, ( Part -6) April 2015, pp.60-65 www.ijera.com 65 | P a g e Diffusion Model”, International Journal of Image Processing (IJIP), Book: 2008 Volume 2, Issue 1, Publishing Date: 28-02 - 2008, Proceedings ISSN (Online): 1985- 2304. [5] http://www.improvedoutcomes.com/docs/ WebSiteDocs/Clustering/K-Means_Cluste ring_Overview.htm [6] https://sites.google.com/site/dataclusteringa lgorithms/fuzzy-c-means-clustering-algorith m [7] S. L. Bangare, P. S. Bangare, S. T. Patil, T. V. Rao, “Various Image Segmentation Techniques- focusing on Brain MRI Images - A Review”, National Conference on Latest Trends in Electronics & Telecomm. (NCLTE-2013).