3. Submitted by
Keshob kumar ghose
2016000300001
Batch 27 sec:A
Submitted to
Mosiqur Rahman
Senior lecturer
Department of pharmacy
Southeast university
4.
5. Staphylococcus is a genus of gram positive
bacteria. It contains about 40 species.
The three main clinically important are:
S. aureus
pathogenic and commensally found in nose.
S. epidermis
Is commensal of the skin, but also found in
immune suppressed patient.
S. saprophyticus
Is predominantly implicated in genitourinary
tract.
11. abscess (Latin: abscessus) is a collection of pus
that has built up within the tissue of the body.
Signs and symptoms of abscesses include
redness, pain, warmth, and swelling
15. It is available in Bangladesh in different brand
name . Some are
16. Flucloxacilin inhibits the 3rd and last step of
bacterial cell wall synthesis by binding to
specific penicillin-binding proteins (PBPs)
located inside the bacterial cell wall. It is
activate against penicillinase-producing and
non-penicilinnase producing staphylococci.
17.
18. Staphylococcus epidermidis is spread by skin-
to-skin contact. However, infection is
not spread unless a person has an open wound
and the bacteria gain entry into this wound. In
hospitals it can spread by medical instruments,
stethoscopes, oxygen masks, bed lining and so
on.
21. Cephalosporin exert bactericidal activity by
interfering with the later stages of bacterial cell
wall synthesis through inactivation of one or more
penicillin-binding proteins and inhibiting cross-
linking of the peptidoglycan structure.
22. Staphylococcus saprophyticus as a common
cause of urinary tract infections. ... In young
women, S. saprophyticus is, after Escherichia
coli, the second-most-frequent causative agent
of acute UTI. Patients with UTI caused
by S. saprophyticus usually present with
symptomatic cystitis.
23.
24. Treatment. S. saprophyticus urinary tract
infections are usually treated with
trimethoprim-sulfamethoxazole or with a
quinolone such as norfloxacin.
25. Norfloxacin inhibits the action of DNA gyrase in
DNA replication, transcription, repair,
recombination and transposition.
