A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms-8396

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http://hdl.handle.net/1926/561

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A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms Martin Urschler, Stefan Kluckner, Horst Bischof Institute for Computer Graphics and Vision, Graz, University of Technology, Austria

Motivation Validation very difficult! ,[object Object],[object Object],[object Object],[object Object],We claim: Standardizing Evaluation Protocols at least as important as Developing Novel Methods! -> Put framework to discussion: - Open-source community effort - Instantiate framework by showing sample evaluation Presented algorithm at last years MICCAI. Nonlinear Image Registration

Contents ,[object Object],[object Object],[object Object],[object Object],[object Object]

The Nonlinear Registration Problem ,[object Object],h(x) Base Illustration taken from ITK Software Guide. SSD, NCC, Mutual Information, … B-Spline, Thin-Plate Spline, Def Field, … Gradient Descent, BFGS, … Intensity-Based, Feature-Based, …

Medical Applications of Nonlinear Image Registration ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Lung Perfusion for Pulmonary Embolism Detection [Wildberger et al.] Validation Study: Atlas-based Brain Volume Segmentation from MRI Images [Ng02] – taken from ITK Documentation Inter- & Intra-Modality Inter- & Intra-Subject No Ground Truth or Gold Standards Highly Ill-Posed How should we reach clinical acceptance?

Related Work on Evaluation (Frameworks) There exist some good ideas for evaluation in (Medical) Computer Vision! VALMET Segmentation Evaluation [Gerig et al] Community would benefit from open-source implementation! MICCAI 2007 Segmentation Challenge Workshop Multi-View 3D Reconstruction [Seitz et al] Stereo Reconstruction [Scharstein et al] Middlesbury Retrospective Evaluation of Intersubject Brain Registration [Hellier et al] Retrospective Rigid Registration Evaluation Project [West et al] NIREP (Inter-subject Brain-Registration Evaluation) [Christensen et al] Validation of Nonrigid Image Registration Using FEM [Schnabel et al] Segmentations are compared!

Open Science Evaluation Framework ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Registration Algorithms Public domain data sets Synthetic Deformations Similarity Measures Python Framework as Glue

Synthetic Deformations Used ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Data Sets and Algorithms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Quantitative Measures ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

A Sample Evaluation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

A Sample Evaluation Simulated Data Difference to Original Standard Demons

A Sample Evaluation - Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Further Work ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms-8396

1. A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms Martin Urschler, Stefan Kluckner, Horst Bischof Institute for Computer Graphics and Vision, Graz, University of Technology, Austria

6. Related Work on Evaluation (Frameworks) There exist some good ideas for evaluation in (Medical) Computer Vision! VALMET Segmentation Evaluation [Gerig et al] Community would benefit from open-source implementation! MICCAI 2007 Segmentation Challenge Workshop Multi-View 3D Reconstruction [Seitz et al] Stereo Reconstruction [Scharstein et al] Middlesbury Retrospective Evaluation of Intersubject Brain Registration [Hellier et al] Retrospective Rigid Registration Evaluation Project [West et al] NIREP (Inter-subject Brain-Registration Evaluation) [Christensen et al] Validation of Nonrigid Image Registration Using FEM [Schnabel et al] Segmentations are compared!

8. Open Science Evaluation Framework

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13. A Sample Evaluation Simulated Data Difference to Original Standard Demons

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A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms-8396

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