SlideShare a Scribd company logo
1 of 41
Viva-Voce Presentation 2011 CRP Study 2008-2010 Date: 21 st  April 2011 Time: 3.00pm Venue: USM
ASSESSMENT OF ECONOMIC, CLINICAL AND HUMANISTIC OUTCOMES OF PATIENTS WITH ACUTE CORONARY SYNDROME IN THE CARDIAC REHABILITATION PROGRAM   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Background ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
General Phases in Cardiac Rehabilitation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],American Association of Cardiovascular & Pulmonary Rehabilitation.  AACVPR Cardiac Rehabilitation Resource Manual  (2006).  USA, Human Kinetics, Library of Congress. Web site: http://www.humakinetics.com/
Outline of CRP
Phase I, Stage I CRP (First assessment) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],05/05/11 5th Biennial Meeting on Cardiopulmonary Bypass
Phase I, Stage II CRP (CTW) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phase I, Stage III Bed side and discharge counselling  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phase II CRP Group counseling (The ideal) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Problem Statements ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Study Objectives ,[object Object],[object Object],[object Object]
METHODOLOGY
Measurement for Interventional Outcomes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Brazier,  J. E., Dixon, S., & Ratcliffe, J. (2009). The role of patient preferences in cost-effectiveness analysis: a conflict of values? PharmacoEconomics, 27(9), 705-712.  Van Stel,  H., & Buskens, E. (2006). Comparison of the SF-6D and the EQ-5D in patients with coronary heart disease.  Health and Quality of Life Outcomes, 4(1), 20
Methodology:  Data collection ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CCRP CONTROL MCRP Inpatient Outpatient
EQ-5D Utility Score A Comparison of  Preference-based from EQ-5D and SF-36 SF-6D program in SPSS by Sheffield University ScHARR  Estimating a preference-based index from the SF-6D SF-36 SF-6D Utility Score
Statistical Analysis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
RESULTS
Screening and Recruitment process from  Jan-Dec 2008
At baseline there were no difference in demographic, socioeconomic background, or physical characteristic data
Clinical & Physical Characteristic
[object Object],[object Object],Baseline  vs. Malaysian Norms  by  Azman et al., (2003)  * Six months assessment *  Azman A.B ., Sararaks S., Rugayah B., Low L.L., Azian A.A., Geeta S., Tiew C.T. (2003). Quality of life of the Malaysian general population: Results from a postal survey using the SF-36. Med J Malaysia, 58(5):694-711
[object Object],[object Object],[object Object],Baseline 12-months assessment
Nnot MCRP
M inimal  C linically  I mportant  D ifference (MCID) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Tubach, F., Giraudeau, B., & Ravaud, P. (2009).  The variability in minimal clinically important difference and patient acceptable symptomatic state values did not have an impact on treatment effect estimates. Journal of Clinical Epidemiology, 62(7), 725-728.
Mean Differences after 12 months follow up (MCID of 20 points)
MCRP  CCRP  control r =  0.805, p<0.01
ICER = Incremental cost annually /  Incremental Utility Score  How much it cost (unit per health benefit)?
[object Object]
MCRP group
Bar chart of compliance score for 6- and 12-month follow-up ,[object Object],[object Object]
Individual and combined outcome measures of the primary end point at 12 months follow-up in the three groups ,[object Object]
Discussion ,[object Object],[object Object],[object Object],[object Object],[object Object]
CONCLUSION
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Limitation ,[object Object],[object Object],[object Object],[object Object],[object Object]
Strength Of This Study ,[object Object],[object Object],[object Object],[object Object]
Suggestion for future research: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recommendations ,[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THANK YOU Sarawak General Hospital It is not the number that count, but the heart….

More Related Content

What's hot

Ecg interpretation
Ecg interpretationEcg interpretation
Ecg interpretation
Pk Doctors
 
Основы эхокардиографии плода. Часть 2
Основы эхокардиографии плода. Часть 2Основы эхокардиографии плода. Часть 2
Основы эхокардиографии плода. Часть 2
andrii68
 

What's hot (20)

ISCHEMIA Trial
ISCHEMIA TrialISCHEMIA Trial
ISCHEMIA Trial
 
St segment elevations
St  segment elevationsSt  segment elevations
St segment elevations
 
Evaluation and management of Pacemaker malfunction
Evaluation and management of Pacemaker malfunctionEvaluation and management of Pacemaker malfunction
Evaluation and management of Pacemaker malfunction
 
Ecg interpretation
Ecg interpretationEcg interpretation
Ecg interpretation
 
Echocardiography for Acute Coronary Syndrome
Echocardiography for Acute Coronary SyndromeEchocardiography for Acute Coronary Syndrome
Echocardiography for Acute Coronary Syndrome
 
Stable Ischemic Heart Disease Guideline
Stable Ischemic Heart Disease GuidelineStable Ischemic Heart Disease Guideline
Stable Ischemic Heart Disease Guideline
 
Stemi guideline esc 2017
Stemi guideline esc 2017Stemi guideline esc 2017
Stemi guideline esc 2017
 
QRS axis change during ventricualr tachycardia (VT)
QRS axis   change during ventricualr tachycardia (VT)QRS axis   change during ventricualr tachycardia (VT)
QRS axis change during ventricualr tachycardia (VT)
 
SYNTAX TRIAL.pptx
SYNTAX TRIAL.pptxSYNTAX TRIAL.pptx
SYNTAX TRIAL.pptx
 
CPR in Covid-19.pptx
CPR in Covid-19.pptxCPR in Covid-19.pptx
CPR in Covid-19.pptx
 
Bradyarryhthmias
BradyarryhthmiasBradyarryhthmias
Bradyarryhthmias
 
Airway management
Airway management Airway management
Airway management
 
Acls 2020
Acls 2020Acls 2020
Acls 2020
 
Ecg quiz @ SEMICON 1018
Ecg quiz @ SEMICON 1018Ecg quiz @ SEMICON 1018
Ecg quiz @ SEMICON 1018
 
CARDIOPULMONARY RESUSCITATION- BLS & ACLS-2020 AHA UPDATE
CARDIOPULMONARY RESUSCITATION- BLS & ACLS-2020 AHA UPDATECARDIOPULMONARY RESUSCITATION- BLS & ACLS-2020 AHA UPDATE
CARDIOPULMONARY RESUSCITATION- BLS & ACLS-2020 AHA UPDATE
 
Mapca 1
Mapca 1Mapca 1
Mapca 1
 
Wpw syndrome jadi
Wpw syndrome jadiWpw syndrome jadi
Wpw syndrome jadi
 
How to perform Trans-Septal Puncture
How to perform Trans-Septal PunctureHow to perform Trans-Septal Puncture
How to perform Trans-Septal Puncture
 
ACLS 2015
ACLS 2015ACLS 2015
ACLS 2015
 
Основы эхокардиографии плода. Часть 2
Основы эхокардиографии плода. Часть 2Основы эхокардиографии плода. Часть 2
Основы эхокардиографии плода. Часть 2
 

Similar to CARDIAC REHABILITATION IN SARAWAK GENERAL HOSPITAL IN MALAYSIA Research Area: (FCA 701/ 48), Cardiovascular Pharmacy, Reference No under NIH KKM MRG-2007-11 Viva lawrence 2011

Balderman2019 thoracic outlet syndrome
Balderman2019 thoracic outlet syndromeBalderman2019 thoracic outlet syndrome
Balderman2019 thoracic outlet syndrome
NistaraSinghChawla
 
Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx
     Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx     Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx
Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx
robert345678
 
Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...
Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...
Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...
ijtsrd
 

Similar to CARDIAC REHABILITATION IN SARAWAK GENERAL HOSPITAL IN MALAYSIA Research Area: (FCA 701/ 48), Cardiovascular Pharmacy, Reference No under NIH KKM MRG-2007-11 Viva lawrence 2011 (20)

Economic And Humanistic Outcomes Of Post Acs In Cardiac Rehabilitation Progra...
Economic And Humanistic Outcomes Of Post Acs In Cardiac Rehabilitation Progra...Economic And Humanistic Outcomes Of Post Acs In Cardiac Rehabilitation Progra...
Economic And Humanistic Outcomes Of Post Acs In Cardiac Rehabilitation Progra...
 
The Clinical Pharmacist in Cardiac Rehabilitation Phase I at Sarawak General ...
The Clinical Pharmacist in Cardiac Rehabilitation Phase I at Sarawak General ...The Clinical Pharmacist in Cardiac Rehabilitation Phase I at Sarawak General ...
The Clinical Pharmacist in Cardiac Rehabilitation Phase I at Sarawak General ...
 
Ari Refs
Ari RefsAri Refs
Ari Refs
 
Analysis of Medication Possession Ratio for Improved Blood Pressure Control
Analysis of Medication Possession Ratio for Improved Blood Pressure ControlAnalysis of Medication Possession Ratio for Improved Blood Pressure Control
Analysis of Medication Possession Ratio for Improved Blood Pressure Control
 
ERAS and regional anesthesia at PGA 2015
ERAS and regional anesthesia at PGA 2015ERAS and regional anesthesia at PGA 2015
ERAS and regional anesthesia at PGA 2015
 
Integrative Telerehabilitation Strategy after Acute Coronary Syndrome
Integrative Telerehabilitation Strategy after Acute Coronary SyndromeIntegrative Telerehabilitation Strategy after Acute Coronary Syndrome
Integrative Telerehabilitation Strategy after Acute Coronary Syndrome
 
Functional scales in cardio pulmonary condition
Functional scales in cardio pulmonary condition Functional scales in cardio pulmonary condition
Functional scales in cardio pulmonary condition
 
AE poster
AE posterAE poster
AE poster
 
Introducción: de la investigación a la práctica. ¿Qué cambia en la vida real?
Introducción: de la investigación a la práctica. ¿Qué cambia en la vida real?Introducción: de la investigación a la práctica. ¿Qué cambia en la vida real?
Introducción: de la investigación a la práctica. ¿Qué cambia en la vida real?
 
Balderman2019 thoracic outlet syndrome
Balderman2019 thoracic outlet syndromeBalderman2019 thoracic outlet syndrome
Balderman2019 thoracic outlet syndrome
 
ARE WE USING THE RIGHT OUTCOME MEASURE TO ASCERTAIN PATIENT BENEFIT FROM DRUG...
ARE WE USING THE RIGHT OUTCOME MEASURE TO ASCERTAIN PATIENT BENEFIT FROM DRUG...ARE WE USING THE RIGHT OUTCOME MEASURE TO ASCERTAIN PATIENT BENEFIT FROM DRUG...
ARE WE USING THE RIGHT OUTCOME MEASURE TO ASCERTAIN PATIENT BENEFIT FROM DRUG...
 
Pmr buzz magazine aug 2020 rt all
Pmr buzz magazine aug 2020 rt  allPmr buzz magazine aug 2020 rt  all
Pmr buzz magazine aug 2020 rt all
 
Actigraphy as a Metric in PAH Research and Clinical Care
Actigraphy as a Metric in PAH Research and Clinical CareActigraphy as a Metric in PAH Research and Clinical Care
Actigraphy as a Metric in PAH Research and Clinical Care
 
Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx
     Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx     Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx
Effectiveness of Aerobic Exercise on Ambulatory Blood P.docx
 
Whistler Anesthesia Symposium Regional Anesthesia Outcomes 2017
Whistler Anesthesia Symposium Regional Anesthesia Outcomes 2017Whistler Anesthesia Symposium Regional Anesthesia Outcomes 2017
Whistler Anesthesia Symposium Regional Anesthesia Outcomes 2017
 
20150300.0 00014
20150300.0 0001420150300.0 00014
20150300.0 00014
 
Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...
Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...
Effectiveness of Nurse Led Heart Failure Management Program on Quality of Lif...
 
Osteoarthritis: Structural Endpoints for the Development of Drugs, Devices, a...
Osteoarthritis: Structural Endpoints for the Development of Drugs, Devices, a...Osteoarthritis: Structural Endpoints for the Development of Drugs, Devices, a...
Osteoarthritis: Structural Endpoints for the Development of Drugs, Devices, a...
 
High intensity interval-training improves metabolic syndrome
High intensity interval-training improves metabolic syndromeHigh intensity interval-training improves metabolic syndrome
High intensity interval-training improves metabolic syndrome
 
D045023028
D045023028D045023028
D045023028
 

Recently uploaded

Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
9953056974 Low Rate Call Girls In Saket, Delhi NCR
 
Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available
Dipal Arora
 

Recently uploaded (20)

Call Girls Ooty Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Ooty Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Ooty Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Ooty Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
 
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
 
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
 
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
VIP Service Call Girls Sindhi Colony 📳 7877925207 For 18+ VIP Call Girl At Th...
 
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
 
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
 
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Cuttack Just Call 9907093804 Top Class Call Girl Service Available
 
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
 
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
Best Rate (Hyderabad) Call Girls Jahanuma ⟟ 8250192130 ⟟ High Class Call Girl...
 
Call Girls Kochi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kochi Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Kochi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kochi Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service AvailableCall Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
Call Girls Gwalior Just Call 8617370543 Top Class Call Girl Service Available
 
Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Aurangabad Just Call 8250077686 Top Class Call Girl Service Available
 
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...Top Rated  Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
Top Rated Hyderabad Call Girls Erragadda ⟟ 9332606886 ⟟ Call Me For Genuine ...
 
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
 
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
 
Call Girls Visakhapatnam Just Call 9907093804 Top Class Call Girl Service Ava...
Call Girls Visakhapatnam Just Call 9907093804 Top Class Call Girl Service Ava...Call Girls Visakhapatnam Just Call 9907093804 Top Class Call Girl Service Ava...
Call Girls Visakhapatnam Just Call 9907093804 Top Class Call Girl Service Ava...
 
Call Girls Jabalpur Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Jabalpur Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Jabalpur Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Jabalpur Just Call 8250077686 Top Class Call Girl Service Available
 
Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...
 
(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...
(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...
(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...
 

CARDIAC REHABILITATION IN SARAWAK GENERAL HOSPITAL IN MALAYSIA Research Area: (FCA 701/ 48), Cardiovascular Pharmacy, Reference No under NIH KKM MRG-2007-11 Viva lawrence 2011

Editor's Notes

  1. Retrieving previous history of medication- home, GP, herbal, supplements and so forth. Brief of his/her condition and what have been done Early education of medication given: IV administration, Enoxaparin, infusion GTN, Dopamine, Dobutamine, Midazolam, Morphine, drips, Heparin, amiodarone etc. Oral medication : aspirin, metoprolol, ACEinhibitor, statin, warfarin Early intervention of Side effect of drugs administered. Such as Aspirin, Heparin, Amiodarone, Enoxaparin
  2. BRUM study. Nonadherence to prescribed medications bypatients with coronary heart disease (CHD) is associated with an increased incidence of adverse cardiovascular events, but it is not known whether self-reported nonadherence can identify patients at greatest risk of such events. Nonadherence to physician treatment recommendations is an increasingly recognized cause of adverse outcomes and increased health care costs, particularly among patients with cardiovascular disease
  3. Clinical &amp; Physical Characteristic
  4. Several dimensions of HRQOL measures were found inproved in MCRP. Comparison of mean difference from baseline MCRP (+10.57; 95%CI: -2.09, 23.23) Reported less bodily pain (BP) than CCRP (+3.72, 95%CI:-8.94, 16.39) and Control (-4.16, 95%CI: -14.92, 6.59).
  5. Results For a 0-100 score and MCID values from -40 to -10, the difference in success rate between arms ranges from 7.9% to 9.9% (ES = 0.25) and from 15.9% to 19.7% (ES = 0.50). For PASS values from 20 to 50, the difference in success rate between arms ranges from 7.1% to 9.9% (ES = 0.25) and from 15.6% to 19.7% (ES = 0.50).Conclusion The MCID or PASS value has a low impact on the difference in the success rate between the arms in a trial. Tubach, F., Giraudeau, B., &amp; Ravaud, P. (2009). The variability in minimal clinically important difference and patient acceptable symptomatic state values did not have an impact on treatment effect estimates. Journal of Clinical Epidemiology, 62(7), 725-728. The minimal important difference (MID), from the patient perspective, can be defined as &amp;quot;the smallest difference in score in the domain of interest which patients perceive as beneficial and which would cause clinicians to consider a change in patient&apos;s management&amp;quot;. (Jaeschke et al., 1989; Fayers &amp; Machin, 2007).
  6. BRUM study. Nonadherence to prescribed medications bypatients with coronary heart disease (CHD) is associated with an increased incidence of adverse cardiovascular events, but it is not known whether self-reported nonadherence can identify patients at greatest risk of such events. Nonadherence to physician treatment recommendations is an increasingly recognized cause of adverse outcomes and increased health care costs, particularly among patients with cardiovascular disease
  7. Table 3.3 Rx RM 3143, MCRP 3214 CCRP 2151 control