This document summarizes research on the relationship between coca cultivation, deforestation, and biodiversity in forest frontier regions. The key points are: 1. Direct deforestation from coca plots is relatively small, but indirect effects on broader deforestation rates are larger. Regions with more coca cultivation see higher overall deforestation. 2. In Bolivia, periods with more coca production corresponded to higher deforestation rates. 3. While coca cultivation directly impacts small areas, its presence in regions with endemic species can still threaten biodiversity through indirect effects on habitat loss. More detailed analysis is needed of its impacts on threatened species.