1. DNA SEQUENCING IDENTIFIES METABOLIC DISEASES AND ELUSIVE Z-DNA FOUND ON NUCLEOSOMES. María Alejandra Tobón Arango Medicine Student .

4. DNA sequence is useful in the study of biological processes, for example the mitochondrial diseases, which are disorders resulting from deficiency of one or more proteins located in mitochondria and they are unspecific diseases. The B-DNA form of DNA, can be transformed into the form Z-DNA in a nucleosome, forming a Z-nucleosome that could contribute to the regulation of protein expression.

9. I think it is a wonderful technological advance in the area of health, because it contributes to good medical practice to become an indispensable ally in diagnosing a mitochondrial disease, which is a delayed process if it is realized with the conventional methods. With the technique of DNA sequencing, the identification process of mitochondrial diseases is not only 100% sure, it is extremely fast, which also allows to implement in a treatment in the right time to those who suffer from this disease that entails severe repercussions as blindness, seizures, respiratory diseases and even death.

14. This new is evidence that if we use science, technology and knowledge as essential tools of the foundations of medicine, medical practice taking into account ethical considerations necessary for each particular case, it becomes an art where combine the forward and the clear principle of beneficence that is inherent in medicine. Here explain interesting situations in which intervention is possible in the genome of an individual, delaying or advancing natural processes of genetic origin, that for many people is unethical, but when it comes to the welfare of a person and improve their physical and mental condition, I personally say that we should not think twice about taking action and taking part in the fantastic studies such as Z-DNA form of DNA for helping them.

19. -MARTINEZ SÁNCHEZ, Lina María. Biología molecular. 6. ed. Medellín: UPB. Fac. de Medicina, 2012. 56 p. -Wendy Zukerman. DNA sequencing quickly identifies metabolic diseases. Rev. Méd Science Translational Medicine [Magazine on the internet]. 2012 Jan [cited on 2012 January 27]. Available in: http://www.newscientist.com/article/dn21391-first-diagnosis-of-disease-by-dna sequencing.html DOI: 10.1126/scitranslmed.3003310 -Niveen Mulholland, Yan Xu, Hiroshi Sugiyama, Keji Zhao. Elusive Z-DNA Found On Nucleosomes. Rev. Méd ScienceDaily [Magazine on the internet]. 2012 Jan [cited on 2012 January 27] 2 (1): 3. Available in: http://www.sciencedaily.com/releases/2012/01/120120183042.htm DOI: 10.1186/2045-3701-2-3

20. THANKS…