I gave this presentation (slides only) at the Dutch postdoc retreat on June 25 2009. I was asked to talk about my move from a PhD in cell biology to running your own software company. I decided that telling my specific story wouldn't be very interesting to all, instead I tried to distill the 10 lessons I learned to help people understand science and decide whether they should stay or leave science. A version with notes is also available. Big thanks to Matt Wood for his slides design.

1. Playing Pyramid Games
Alexander Griekspoor

2. 1

3. Money 1 Air
10

4. Money 1 Air
10
More Money Thin Air
100

5. Money 1 Air
10
More Money Thin Air
Loads of 100 Very Thin
Money Air
1000
Image source: wikipedia article on Madoff

6. PI
Postdoc You!
Graduate Student

7. Science == Pyramid Game

8. Game Theory

9. 10 rules
that made me
understand
Science

10. ...and step out of it.

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Game Theory
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Mekentosj Software was obtained.
disclaimer
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Documentation are being licensed to U.S. Government end users (a) only as Commercial Items and (b) with only those rights as are granted to all other end users pursuant to
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12. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Rule1
of pyramid games

13. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
You don’t talk about
pyramid games

14. PI
Postdoc You!
Graduate Student

15. PI
You!
Postdoc
Graduate Student

16. Find yourself
a different job!

17. True.

18. True.
But not me.

19. Think again

20. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Rule2
of pyramid games

21. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
The game is not Fair

22. “I work as hard as the girl
at the next bench, she gets
a Nature paper, I don’t.
Science is not fair.”

23. Science doesn’t
care about you.

24. But you do!

25. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Not everyone is
suited for the game

26. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
It’s as important to discover
what you don’t love doing, as
it is to find out what you do
You need Passion

27. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Think beyond the
next step

28. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Try new things!
Spread the risk Collaborate!
Do what you love
doing!

29. “Making a career in
science is all about luck.”

30. True.

31. Bullshit

32. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Create your own luck

33. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
work hard

34. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Bend the rules (carefully)
Distinguish
Be creative yourself!
Think outside the box
pyramid!

35. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
The most important rule
of pyramid games

36. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Don’t be afraid to step out

37. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Stepping out != Failure
On the contrary!

38. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
One more rule...

39. ➊ ➋ ➌ ➍ ➎ ➏ ➐ ➑ ➒ ➓
Pyramid games are
everywhere...

40. mekentosj@gmail.com