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Experimental Research
                                    by Mary Macin




Tuesday, February 15, 2011                           1
Experimental Research vs. Other Methods

                                ❖ Can test for cause/effect relationships
                                ❖ Manipulation of independent variable(s)




                                    Simply put:
                                      Decisions about the forms and values of the IV, as
                                      well as about which group receives which treatment
                                      are at the sole discretion of the researcher




Tuesday, February 15, 2011                                                                 2
Variables in Experimental Research

                              ❖   Independent Variable:
                                    ❖ Experimental Variable, Cause, or Treatment
                                    ❖ The activity or characteristic the researcher believes
                                      makes a difference

                              ❖   Dependent Variable:
                                    ❖ Criterion Variable, Effect, or Posttest
                                    ❖ Outcome of the study
                                    ❖ Difference in group(s) that occurs as a result of the
                                      manipulation of the IV
                                    ❖ Only constraint: must represent a measurable
                                      outcome




Tuesday, February 15, 2011                                                                     3
Characteristics of Experimental Research

                               ❖   Demanding & Productive, but...
                                     ❖   Produce the soundest evidence of hypothesized cause-effect
                                         relationships


                               ❖   Difference between Correlational & Experimental
                                   Research:
                                     ❖ Correlational can be used to predict a specific score for a
                                       specific individual
                                     ❖ Experimental predicts more global results*




Tuesday, February 15, 2011                                                                           4
Steps in Experimental Research Study

                               1. Select and define problem.

                               2. Select subjects and [measurement] instruments.

                               3. Select design.

                               4.Execute procedures.

                               5. Analyze data.

                               6.Formulate conclusions.




Tuesday, February 15, 2011                                                         5
Role of the Researcher

                             ❖   Forms or selects groups
                             ❖   Decides what will happen to each group
                             ❖   Attempts to control all variables and factors
                             ❖   Observes and measures effect on the groups


                                Every effort is made to make sure the 2 groups have
                             equivalent variables—except for the independent variable.




Tuesday, February 15, 2011                                                               6
Two Groups

                             ❖   Experimental Group
                                    ❖   Receives the new treatment being investigated

                             ❖   Control Group
                                    ❖ Receives a different treatment; or
                                    ❖ Receives same treatment as usual (i.e. is left alone)



                                 The Control Group is needed in order to identify/measure any
                                 differences observed as a result of the differing treatments




Tuesday, February 15, 2011                                                                      7
Potential Issues in Experimental Research

                                ❖   Experimental treatment not given adequate time to
                                    take effect
                                    ❖   Experimental group should be exposed to treatment for a long
                                        enough period of time for the treatment to work

                                ❖   Treatments received by the 2 groups are not
                                    “different enough”
                                    ❖   No difference between the groups will be found if the
                                        experimental treatment and the control treatment are too
                                        similar




Tuesday, February 15, 2011                                                                             8
Experimental Validity

                             ❖   Experiments are considered valid if:
                                   ❖   The results obtained are only due to the manipulation
                                       of the independent variable




                             ❖   Two conditions must be met:
                                   ❖   Experiment has internal validity
                                   ❖   Experiment has external validity




Tuesday, February 15, 2011                                                                     9
Internal Validity
                             ❖   Observed differences on the dependent variable are the direct result of the
                                 researcher’s manipulation of the independent variable.

                             ❖   Campbell & Stanley (1971) identified 8 threats to internal validity:
                                 ❖   History - becomes more likely the longer a study is; caused by external events.
                                 ❖   Maturation - physical/mental changes occurring in subjects over time; more likely to occur when study is extended over a
                                     long period of time.
                                 ❖   Testing (pretest sensitization) - result of higher scores on a posttest due to participants having taken a pretest; unlike
                                     above, more likely to occur when there are short intervals between testing.
                                 ❖   Instrumentation - lack of consistency between measuring instruments; data collection leads to unreliable/invalid results.
                                 ❖   Statistical Regression - tendency for some scores to move towards the mean score; participants who score the highest and
                                     lowest on a pretest are more likely to score lower and higher (respectively) on a posttest.
                                 ❖   Differential Selection of Subjects - differences already present between two pre-formed groups could account for
                                     differences in posttest results.
                                 ❖   Mortality (attrition) - occurs most often in long-term studies; refers to participants who drop out of a group potentially
                                     sharing some characteristic that affects the significance of the study.*
                                 ❖   Selection-Maturation Interaction, Etc. - if pre-formed groups are used, one group may be at an (dis)advantage due to
                                     factors of maturation; the “etc.” refers to the fact that selection can also interact in this way with other factors such as
                                     history, testing, instrumentation, etc.




Tuesday, February 15, 2011                                                                                                                                          10
External Validity
                             ❖   Results of the experiment are generalizable to groups and environments outside of the experiment;
                                 results of the study can be reconfirmed with other groups, in other settings, and at other times (if
                                 the conditions are similar to those present in the experiment).

                             ❖   Bracht & Glass (1968) identified 6 threats to external validity:
                                 ❖   Pretest-Treatment Interaction - participants react differently to a treatment because they have been pretested; pretests may alert
                                     participants to the make-up of the treatment; therefore, results can only be generalized to other pretested groups.
                                 ❖   Multiple-Treatment Interference - the same participants receive the same treatment in succession; effects are carried-over from the first
                                     treatment making it hard to determine the effectiveness of the second treatment.
                                 ❖   Selection-Treatment Interaction - occurs when participants are not randomly selected for the treatments they receive; can occur when
                                     participants are a pre-formed group or an individual; limits the generalizability of the results.
                                 ❖   Specificity of Variables - does not depend on the experimental design chosen; threatens validity when a study is conducted:
                                        ❖   with a specific kind of subject;
                                        ❖   based on a particular definition of the independent variable;
                                        ❖   using specific measuring instruments;
                                        ❖   at a specific time; and
                                        ❖   under a specific set of circumstances.
                                 ❖   Experimenter Effects - experimenter unintentionally affects the implementation of the study’s procedures, the behavior of the participants,
                                     or the assessment of participant behavior, thereby affecting the results of the study.
                                 ❖   Reactive Arrangements - factors associated with how a study is conducted effectively influence the feelings and attitudes of the
                                     participants; affects generalizability of the results.




Tuesday, February 15, 2011                                                                                                                                                       11
Extraneous Variables

                             ❖   The control of extraneous variables is vital to the success of
                                 an experiment.

                             ❖   Extraneous variables can be controlled through:
                                 ❖   Randomization - subjects should be randomly selected for participation and randomly assigned to groups; randomizing
                                     selection should be attempted whenever possible
                                 ❖   Matching - researcher pairs up participants with matching (similar) scores or characteristics (gender, IQ, location), then
                                     randomly assigns each participant to a different group than their counterpart; this ensures that the pair with matching
                                     IQ scores are not in the same group
                                 ❖   Comparing homogenous groups or subgroups - group participants according to their similarity/fit into a variable
                                     subgroup (IQ, SAT score); randomly assign half of the subgroup to the experimental group, and the other half of the
                                     subgroup to the control group
                                 ❖   Using subjects as their own controls - the same participants get both treatments (one treatment at a time); controls for
                                     participant differences; can result (negatively) in carry-over effects between the treatments
                                 ❖   Analysis of covariance - statistically equate randomly formed groups on a particular variable; can be used to adjust for
                                     large differences in pretest scores between groups




Tuesday, February 15, 2011                                                                                                                                        12
Group Designs

                             ❖   Two classes of experimental designs:
                                 ❖   Single-Variable: one independent variable; IV is manipulated
                                        ❖   Three types—
                                            ❖ Pre-experimental
                                            ❖ True experimental*
                                            ❖ Quasi-experimental

                                 ❖   Factorial: two or more independent variables; at least one IV
                                     is manipulated
                                        ❖   Elaborate on single-variable designs;
                                        ❖   Investigates each variable independently and in interaction
                                            with other variables;
                                        ❖   Sky’s the limit**




Tuesday, February 15, 2011                                                                                13
Pre-Experimental Designs
                             ❖   One-Shot Case Study —
                                 ❖   One group exposed to one treatment then given posttest
                                     ❖   Don’t know level of group knowledge before the treatment!
                                     ❖   Sources of invalidity are not controlled!

                             ❖   One-Group Pretest-Posttest Design —
                                 ❖   One group pretested, exposed to one treatment, then posttested
                                     ❖   Still a number of factors affecting validity that are not controlled!
                                     ❖   Other factors may influence any differences observed between the pretest and posttest

                             ❖   Static-Group Comparison —
                                 ❖   At least two groups; first receives new treatment; second receives usual
                                     treatment; both posttested
                                     ❖   Purpose of control group is to show how the experimental (first) group would have performed had
                                         they not received the new treatment
                                     ❖   Effective only to the degree that the two groups are equal to each other




Tuesday, February 15, 2011                                                                                                                14
True Experimental Designs
                             ❖   Pretest-Posttest Control Group Design —
                                 ❖   At least two randomly-assigned groups; both pretested for dependent variable;
                                     one group then receives the new treatment; then both groups are posttested.
                                     ❖   Internal invalidity fully controlled by: random assignment, pretesting, & inclusion of a control group
                                     ❖   Potential risk of interaction between the pretest and the treatment*

                             ❖   Posttest-Only Control Group Design —
                                 ❖   Same as pretest-posttest design, except there is no pretest
                                     ❖   Subjects randomly assigned; exposed to independent variable; then posttested
                                     ❖   Mortality is not controlled for (no pretest), but may not be a problem anyway

                             ❖   Solomon Four-Group Design —
                                 ❖   Random assignment of participants to one of four groups
                                     ❖   Two groups are pretested; two groups are not pretested
                                     ❖   One pretested group & one unpretested group receive the experimental treatment
                                     ❖   All four groups are posttested
                                     ❖   Combination of the two designs (above) - eliminates both sources of internal invalidity!




Tuesday, February 15, 2011                                                                                                                        15
Quasi-Experimental Designs

                             ❖   Nonequivalent Control Group Design —
                                 ❖   Two or more existing groups pretested; administered treatment; and posttested.
                                     ❖   Participants’ assignment to groups is not random; assignment of treatments to groups is random
                                     ❖   Invalidity sources include: regression, selection-treatment interactions (maturation, history, and testing)


                             ❖   Time-Series Design —
                                 ❖   One group repeatedly pretested; administered treatment; repeatedly posttested.
                                     ❖   Elaboration of the one-group pretest-posttest design; involves testing (pre- and post-) more than once
                                     ❖   Advantage lies in confidence gained through significant improvement of group scores between pretests and posttests


                             ❖   Counterbalanced Designs —
                                 ❖   All groups received all treatments; each group receives treatment in a different
                                     order than others.
                                     ❖   Any number of groups can be involved; limited only by the number of treatments; # of groups = # of treatments
                                     ❖   Order of each groups’ receipt of treatment is determined randomly; each group is posttested following each treatment
                                     ❖   Pretest usually not possible and/or feasible; often used on existing groups
                                     ❖   Weakness lies in potential for multiple-treatment interference; thus, should only be used when this is not a concern




Tuesday, February 15, 2011                                                                                                                                      16
Factorial Designs

                             ❖   Two or more independent variables; at least one is
                                 manipulated by researcher
                             ❖   Term “factorial” comes from the use of multiple variables
                                 with multiple levels
                                    ❖ 2 x 2 factorial design*
                                    ❖ Can get very complicated (2 x 3, 3 x 2, etc.)!

                             ❖   Often employed after using a single-variable design;
                                    ❖   “Variables do not operate in isolation”
                             ❖   Studies how variables behave at different levels**




Tuesday, February 15, 2011                                                                   17
Single-Subject Experimental Designs

                             ❖   Also referred to as “single-case experimental designs”
                             ❖   Used when sample size = 1; or for multiple individuals
                                 considered as 1 group
                                   ❖   Variation of the time-series design

                             ❖   Typically used as a study of behavioral change in an
                                 individual
                                   ❖   Participant is own control; exposed to both nontreatment &
                                       treatment phases;
                                   ❖   Individual’s performance measured repeatedly during all phases
                                   ❖   Nontreatment phase = A; Treatment phase = B




Tuesday, February 15, 2011                                                                              18
Validity in Single-Subject Experiments

                               ❖   External Validity
                                   ❖   Frequent criticism due to lack of generalizability
                                   ❖   Can be counteracted through replication


                               ❖   Internal Validity
                                   ❖   Repeated and Reliable Measurement
                                       ❖   If results are to be trusted, treatment must follow exact same procedures every time
                                   ❖   Baseline Stability
                                       ❖   Provides basis for assessing the effectiveness of the treatment; must do enough
                                           baseline measurements to establish a pattern*
                                   ❖   The Single Variable Rule
                                       ❖   Only one variable should be manipulated at any one time!




Tuesday, February 15, 2011                                                                                                        19
Types of Single-Subject Designs

                             ❖   A-B-A Withdrawal Designs --
                                 ❖   The A-B* Design
                                     ❖   Establishment of baseline stability; treatment given
                                     ❖   Improvement during treatment = effectiveness of treatment

                                 ❖   The A-B-A Design
                                     ❖   Adds a second baseline measurement to the A-B design
                                     ❖   Improves validity IF behavior improves during the B phase, and subsequently
                                         deteriorates during the second A phase

                                 ❖   The A-B-A-B Design
                                     ❖   Adds a second treatment phase to the A-B-A design
                                     ❖   Could add strength to experiment IF behavior improves during treatment twice!
                                     ❖   Eliminates ethical concerns from A-B-A design (ending with participant not
                                         receiving potentially effective treatment)




Tuesday, February 15, 2011                                                                                               20
Types of Single-Subject Designs (cont’d)

                               ❖   Multiple-Baseline Designs
                                   ❖   Alternative to the A-B design
                                   ❖   Used when unable to withdraw the treatment, or when it would be unethical to do so
                                   ❖   Three basic types: across behaviors, across subjects, and across settings*


                               ❖   Alternating Treatments Design
                                   ❖   Only valid design for assessing effectiveness of 2+ treatments in a single-subject
                                       context
                                   ❖   Rapid alternation of treatments for a single subject
                                   ❖   Treatments are alternated randomly
                                       ❖   Notice: no withdrawal phase, no baseline phase.
                                       ❖   Allows for the study of multiple treatments quickly and efficiently
                                       ❖   Could introduce multiple-treatment interference




Tuesday, February 15, 2011                                                                                                  21
Data Analysis/Interpretation

                             ❖   Typically involves graphically-represented results

                             ❖   Design must be evaluated for adequacy; then
                                 treatment effectiveness is assessed

                             ❖   Clinical Significance vs. Statistical Significance

                             ❖   t and F tests can be used to test for statistical
                                 significance




Tuesday, February 15, 2011                                                            22
Replicating Results

                             ❖   As results are replicated, confidence in the procedures used grows
                                 ❖   Direct replication
                                     ❖ Replication by the same investigator in the same setting
                                     ❖ [Note] the same or different participants may be used

                                 ❖   Simultaneous replication
                                     ❖   Same problem; same location; and same time
                                 ❖   Systematic replication
                                     ❖   Direct replication with different investigators, behaviors, or settings
                                 ❖   Clinical replication
                                     ❖ Treatment package with 2+ treatments.*
                                     ❖ Designed for participants with complex behavior disorders




Tuesday, February 15, 2011                                                                                        23
Example of Experimental Research


                             ❖   Brain-Computer Interface Project
                                 ❖   University of Illinois at Urbana-Champaign
                                     ❖ Collected brain signals through EEG
                                     ❖ Used one group of 9 individuals
                                     ❖ Allowed “practice” session before testing, but no
                                       pretest was conducted




Tuesday, February 15, 2011                                                                 24
Infamous Cases of Unethical Research
                             ❖   Tuskegee Syphilis Study (1932-1972)
                                 ❖ Nearly 400 African-American men were infected with syphilis
                                 ❖ Study conducted by Public Health Service
                                 ❖ Led to the 1979 Belmont Report (modern foundation for ethical research of
                                   human subjects)

                             ❖   Milgram Obedience to Authority Study (began 1961;
                                 made public 1963)
                                 ❖ Residents of New Haven, CT recruited to participate in a study of “memory and
                                   learning”
                                 ❖ Participants asked to inflict electric shocks in increasing voltages based on
                                   “learner’s” incorrect answers (maximum voltage of 450 volts)
                                 ❖ Study conducted at Yale University; intended to determine whether ordinary
                                   people would follow orders they considered immoral (i.e. Nazi Holocaust/Adolf
                                   Eichmann)

                             ❖   Stanford Prison Experiment (1971)
                                 ❖ 24 students chosen as “prisoners,” while 9 “guards” were assigned to 3 shifts
                                 ❖ Shut down after 6 days (originally intended to take 2 weeks) due to a
                                   deterioration of the experiment’s conditions and structure
                                 ❖ Both prisoners and guards adapted to their given roles--guards becoming
                                   authoritarian and prisoners becoming passive




Tuesday, February 15, 2011                                                                                         25
References

                             Gay, L. R. (1996). Educational research : competencies for analysis and application / L.R. Gay (5th
                             ed.): Englewood Cliffs, N.J. : Merrill, 1996.

                             Milgram experiment. (2011, February 7). In Wikipedia, The Free Encyclopedia. Retrieved from http://
                             en.wikipedia.org/w/index.php?title=Milgram_experiment&oldid=412574744.

                             Stanford prison experiment. (2011, February 11). In Wikipedia, The Free Encyclopedia. Retrieved
                             from http://en.wikipedia.org/w/index.php?title=Stanford_prison_experiment&oldid=413232983.

                             Omar, C., Akce, A., Johnson, M., Bretl, T., Rui, M., Maclin, E. (2011). A Feedback Information-
                             Theoretic Approach to the Design of Brain-Computer Interfaces. [Article]. International Journal of
                             Human-Computer Interaction, 27(1), 5-23. doi: 10.1080/10447318.2011.535749.

                             Tuskegee syphilis experiment. (2011, February 3). In Wikipedia, The Free Encyclopedia. Retrieved
                             from http://en.wikipedia.org/w/index.php?title=Tuskegee_syphilis_experiment&oldid=411791432.




Tuesday, February 15, 2011                                                                                                         26

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Experimental Research Overview

  • 1. Experimental Research by Mary Macin Tuesday, February 15, 2011 1
  • 2. Experimental Research vs. Other Methods ❖ Can test for cause/effect relationships ❖ Manipulation of independent variable(s) Simply put: Decisions about the forms and values of the IV, as well as about which group receives which treatment are at the sole discretion of the researcher Tuesday, February 15, 2011 2
  • 3. Variables in Experimental Research ❖ Independent Variable: ❖ Experimental Variable, Cause, or Treatment ❖ The activity or characteristic the researcher believes makes a difference ❖ Dependent Variable: ❖ Criterion Variable, Effect, or Posttest ❖ Outcome of the study ❖ Difference in group(s) that occurs as a result of the manipulation of the IV ❖ Only constraint: must represent a measurable outcome Tuesday, February 15, 2011 3
  • 4. Characteristics of Experimental Research ❖ Demanding & Productive, but... ❖ Produce the soundest evidence of hypothesized cause-effect relationships ❖ Difference between Correlational & Experimental Research: ❖ Correlational can be used to predict a specific score for a specific individual ❖ Experimental predicts more global results* Tuesday, February 15, 2011 4
  • 5. Steps in Experimental Research Study 1. Select and define problem. 2. Select subjects and [measurement] instruments. 3. Select design. 4.Execute procedures. 5. Analyze data. 6.Formulate conclusions. Tuesday, February 15, 2011 5
  • 6. Role of the Researcher ❖ Forms or selects groups ❖ Decides what will happen to each group ❖ Attempts to control all variables and factors ❖ Observes and measures effect on the groups Every effort is made to make sure the 2 groups have equivalent variables—except for the independent variable. Tuesday, February 15, 2011 6
  • 7. Two Groups ❖ Experimental Group ❖ Receives the new treatment being investigated ❖ Control Group ❖ Receives a different treatment; or ❖ Receives same treatment as usual (i.e. is left alone) The Control Group is needed in order to identify/measure any differences observed as a result of the differing treatments Tuesday, February 15, 2011 7
  • 8. Potential Issues in Experimental Research ❖ Experimental treatment not given adequate time to take effect ❖ Experimental group should be exposed to treatment for a long enough period of time for the treatment to work ❖ Treatments received by the 2 groups are not “different enough” ❖ No difference between the groups will be found if the experimental treatment and the control treatment are too similar Tuesday, February 15, 2011 8
  • 9. Experimental Validity ❖ Experiments are considered valid if: ❖ The results obtained are only due to the manipulation of the independent variable ❖ Two conditions must be met: ❖ Experiment has internal validity ❖ Experiment has external validity Tuesday, February 15, 2011 9
  • 10. Internal Validity ❖ Observed differences on the dependent variable are the direct result of the researcher’s manipulation of the independent variable. ❖ Campbell & Stanley (1971) identified 8 threats to internal validity: ❖ History - becomes more likely the longer a study is; caused by external events. ❖ Maturation - physical/mental changes occurring in subjects over time; more likely to occur when study is extended over a long period of time. ❖ Testing (pretest sensitization) - result of higher scores on a posttest due to participants having taken a pretest; unlike above, more likely to occur when there are short intervals between testing. ❖ Instrumentation - lack of consistency between measuring instruments; data collection leads to unreliable/invalid results. ❖ Statistical Regression - tendency for some scores to move towards the mean score; participants who score the highest and lowest on a pretest are more likely to score lower and higher (respectively) on a posttest. ❖ Differential Selection of Subjects - differences already present between two pre-formed groups could account for differences in posttest results. ❖ Mortality (attrition) - occurs most often in long-term studies; refers to participants who drop out of a group potentially sharing some characteristic that affects the significance of the study.* ❖ Selection-Maturation Interaction, Etc. - if pre-formed groups are used, one group may be at an (dis)advantage due to factors of maturation; the “etc.” refers to the fact that selection can also interact in this way with other factors such as history, testing, instrumentation, etc. Tuesday, February 15, 2011 10
  • 11. External Validity ❖ Results of the experiment are generalizable to groups and environments outside of the experiment; results of the study can be reconfirmed with other groups, in other settings, and at other times (if the conditions are similar to those present in the experiment). ❖ Bracht & Glass (1968) identified 6 threats to external validity: ❖ Pretest-Treatment Interaction - participants react differently to a treatment because they have been pretested; pretests may alert participants to the make-up of the treatment; therefore, results can only be generalized to other pretested groups. ❖ Multiple-Treatment Interference - the same participants receive the same treatment in succession; effects are carried-over from the first treatment making it hard to determine the effectiveness of the second treatment. ❖ Selection-Treatment Interaction - occurs when participants are not randomly selected for the treatments they receive; can occur when participants are a pre-formed group or an individual; limits the generalizability of the results. ❖ Specificity of Variables - does not depend on the experimental design chosen; threatens validity when a study is conducted: ❖ with a specific kind of subject; ❖ based on a particular definition of the independent variable; ❖ using specific measuring instruments; ❖ at a specific time; and ❖ under a specific set of circumstances. ❖ Experimenter Effects - experimenter unintentionally affects the implementation of the study’s procedures, the behavior of the participants, or the assessment of participant behavior, thereby affecting the results of the study. ❖ Reactive Arrangements - factors associated with how a study is conducted effectively influence the feelings and attitudes of the participants; affects generalizability of the results. Tuesday, February 15, 2011 11
  • 12. Extraneous Variables ❖ The control of extraneous variables is vital to the success of an experiment. ❖ Extraneous variables can be controlled through: ❖ Randomization - subjects should be randomly selected for participation and randomly assigned to groups; randomizing selection should be attempted whenever possible ❖ Matching - researcher pairs up participants with matching (similar) scores or characteristics (gender, IQ, location), then randomly assigns each participant to a different group than their counterpart; this ensures that the pair with matching IQ scores are not in the same group ❖ Comparing homogenous groups or subgroups - group participants according to their similarity/fit into a variable subgroup (IQ, SAT score); randomly assign half of the subgroup to the experimental group, and the other half of the subgroup to the control group ❖ Using subjects as their own controls - the same participants get both treatments (one treatment at a time); controls for participant differences; can result (negatively) in carry-over effects between the treatments ❖ Analysis of covariance - statistically equate randomly formed groups on a particular variable; can be used to adjust for large differences in pretest scores between groups Tuesday, February 15, 2011 12
  • 13. Group Designs ❖ Two classes of experimental designs: ❖ Single-Variable: one independent variable; IV is manipulated ❖ Three types— ❖ Pre-experimental ❖ True experimental* ❖ Quasi-experimental ❖ Factorial: two or more independent variables; at least one IV is manipulated ❖ Elaborate on single-variable designs; ❖ Investigates each variable independently and in interaction with other variables; ❖ Sky’s the limit** Tuesday, February 15, 2011 13
  • 14. Pre-Experimental Designs ❖ One-Shot Case Study — ❖ One group exposed to one treatment then given posttest ❖ Don’t know level of group knowledge before the treatment! ❖ Sources of invalidity are not controlled! ❖ One-Group Pretest-Posttest Design — ❖ One group pretested, exposed to one treatment, then posttested ❖ Still a number of factors affecting validity that are not controlled! ❖ Other factors may influence any differences observed between the pretest and posttest ❖ Static-Group Comparison — ❖ At least two groups; first receives new treatment; second receives usual treatment; both posttested ❖ Purpose of control group is to show how the experimental (first) group would have performed had they not received the new treatment ❖ Effective only to the degree that the two groups are equal to each other Tuesday, February 15, 2011 14
  • 15. True Experimental Designs ❖ Pretest-Posttest Control Group Design — ❖ At least two randomly-assigned groups; both pretested for dependent variable; one group then receives the new treatment; then both groups are posttested. ❖ Internal invalidity fully controlled by: random assignment, pretesting, & inclusion of a control group ❖ Potential risk of interaction between the pretest and the treatment* ❖ Posttest-Only Control Group Design — ❖ Same as pretest-posttest design, except there is no pretest ❖ Subjects randomly assigned; exposed to independent variable; then posttested ❖ Mortality is not controlled for (no pretest), but may not be a problem anyway ❖ Solomon Four-Group Design — ❖ Random assignment of participants to one of four groups ❖ Two groups are pretested; two groups are not pretested ❖ One pretested group & one unpretested group receive the experimental treatment ❖ All four groups are posttested ❖ Combination of the two designs (above) - eliminates both sources of internal invalidity! Tuesday, February 15, 2011 15
  • 16. Quasi-Experimental Designs ❖ Nonequivalent Control Group Design — ❖ Two or more existing groups pretested; administered treatment; and posttested. ❖ Participants’ assignment to groups is not random; assignment of treatments to groups is random ❖ Invalidity sources include: regression, selection-treatment interactions (maturation, history, and testing) ❖ Time-Series Design — ❖ One group repeatedly pretested; administered treatment; repeatedly posttested. ❖ Elaboration of the one-group pretest-posttest design; involves testing (pre- and post-) more than once ❖ Advantage lies in confidence gained through significant improvement of group scores between pretests and posttests ❖ Counterbalanced Designs — ❖ All groups received all treatments; each group receives treatment in a different order than others. ❖ Any number of groups can be involved; limited only by the number of treatments; # of groups = # of treatments ❖ Order of each groups’ receipt of treatment is determined randomly; each group is posttested following each treatment ❖ Pretest usually not possible and/or feasible; often used on existing groups ❖ Weakness lies in potential for multiple-treatment interference; thus, should only be used when this is not a concern Tuesday, February 15, 2011 16
  • 17. Factorial Designs ❖ Two or more independent variables; at least one is manipulated by researcher ❖ Term “factorial” comes from the use of multiple variables with multiple levels ❖ 2 x 2 factorial design* ❖ Can get very complicated (2 x 3, 3 x 2, etc.)! ❖ Often employed after using a single-variable design; ❖ “Variables do not operate in isolation” ❖ Studies how variables behave at different levels** Tuesday, February 15, 2011 17
  • 18. Single-Subject Experimental Designs ❖ Also referred to as “single-case experimental designs” ❖ Used when sample size = 1; or for multiple individuals considered as 1 group ❖ Variation of the time-series design ❖ Typically used as a study of behavioral change in an individual ❖ Participant is own control; exposed to both nontreatment & treatment phases; ❖ Individual’s performance measured repeatedly during all phases ❖ Nontreatment phase = A; Treatment phase = B Tuesday, February 15, 2011 18
  • 19. Validity in Single-Subject Experiments ❖ External Validity ❖ Frequent criticism due to lack of generalizability ❖ Can be counteracted through replication ❖ Internal Validity ❖ Repeated and Reliable Measurement ❖ If results are to be trusted, treatment must follow exact same procedures every time ❖ Baseline Stability ❖ Provides basis for assessing the effectiveness of the treatment; must do enough baseline measurements to establish a pattern* ❖ The Single Variable Rule ❖ Only one variable should be manipulated at any one time! Tuesday, February 15, 2011 19
  • 20. Types of Single-Subject Designs ❖ A-B-A Withdrawal Designs -- ❖ The A-B* Design ❖ Establishment of baseline stability; treatment given ❖ Improvement during treatment = effectiveness of treatment ❖ The A-B-A Design ❖ Adds a second baseline measurement to the A-B design ❖ Improves validity IF behavior improves during the B phase, and subsequently deteriorates during the second A phase ❖ The A-B-A-B Design ❖ Adds a second treatment phase to the A-B-A design ❖ Could add strength to experiment IF behavior improves during treatment twice! ❖ Eliminates ethical concerns from A-B-A design (ending with participant not receiving potentially effective treatment) Tuesday, February 15, 2011 20
  • 21. Types of Single-Subject Designs (cont’d) ❖ Multiple-Baseline Designs ❖ Alternative to the A-B design ❖ Used when unable to withdraw the treatment, or when it would be unethical to do so ❖ Three basic types: across behaviors, across subjects, and across settings* ❖ Alternating Treatments Design ❖ Only valid design for assessing effectiveness of 2+ treatments in a single-subject context ❖ Rapid alternation of treatments for a single subject ❖ Treatments are alternated randomly ❖ Notice: no withdrawal phase, no baseline phase. ❖ Allows for the study of multiple treatments quickly and efficiently ❖ Could introduce multiple-treatment interference Tuesday, February 15, 2011 21
  • 22. Data Analysis/Interpretation ❖ Typically involves graphically-represented results ❖ Design must be evaluated for adequacy; then treatment effectiveness is assessed ❖ Clinical Significance vs. Statistical Significance ❖ t and F tests can be used to test for statistical significance Tuesday, February 15, 2011 22
  • 23. Replicating Results ❖ As results are replicated, confidence in the procedures used grows ❖ Direct replication ❖ Replication by the same investigator in the same setting ❖ [Note] the same or different participants may be used ❖ Simultaneous replication ❖ Same problem; same location; and same time ❖ Systematic replication ❖ Direct replication with different investigators, behaviors, or settings ❖ Clinical replication ❖ Treatment package with 2+ treatments.* ❖ Designed for participants with complex behavior disorders Tuesday, February 15, 2011 23
  • 24. Example of Experimental Research ❖ Brain-Computer Interface Project ❖ University of Illinois at Urbana-Champaign ❖ Collected brain signals through EEG ❖ Used one group of 9 individuals ❖ Allowed “practice” session before testing, but no pretest was conducted Tuesday, February 15, 2011 24
  • 25. Infamous Cases of Unethical Research ❖ Tuskegee Syphilis Study (1932-1972) ❖ Nearly 400 African-American men were infected with syphilis ❖ Study conducted by Public Health Service ❖ Led to the 1979 Belmont Report (modern foundation for ethical research of human subjects) ❖ Milgram Obedience to Authority Study (began 1961; made public 1963) ❖ Residents of New Haven, CT recruited to participate in a study of “memory and learning” ❖ Participants asked to inflict electric shocks in increasing voltages based on “learner’s” incorrect answers (maximum voltage of 450 volts) ❖ Study conducted at Yale University; intended to determine whether ordinary people would follow orders they considered immoral (i.e. Nazi Holocaust/Adolf Eichmann) ❖ Stanford Prison Experiment (1971) ❖ 24 students chosen as “prisoners,” while 9 “guards” were assigned to 3 shifts ❖ Shut down after 6 days (originally intended to take 2 weeks) due to a deterioration of the experiment’s conditions and structure ❖ Both prisoners and guards adapted to their given roles--guards becoming authoritarian and prisoners becoming passive Tuesday, February 15, 2011 25
  • 26. References Gay, L. R. (1996). Educational research : competencies for analysis and application / L.R. Gay (5th ed.): Englewood Cliffs, N.J. : Merrill, 1996. Milgram experiment. (2011, February 7). In Wikipedia, The Free Encyclopedia. Retrieved from http:// en.wikipedia.org/w/index.php?title=Milgram_experiment&oldid=412574744. Stanford prison experiment. (2011, February 11). In Wikipedia, The Free Encyclopedia. Retrieved from http://en.wikipedia.org/w/index.php?title=Stanford_prison_experiment&oldid=413232983. Omar, C., Akce, A., Johnson, M., Bretl, T., Rui, M., Maclin, E. (2011). A Feedback Information- Theoretic Approach to the Design of Brain-Computer Interfaces. [Article]. International Journal of Human-Computer Interaction, 27(1), 5-23. doi: 10.1080/10447318.2011.535749. Tuskegee syphilis experiment. (2011, February 3). In Wikipedia, The Free Encyclopedia. Retrieved from http://en.wikipedia.org/w/index.php?title=Tuskegee_syphilis_experiment&oldid=411791432. Tuesday, February 15, 2011 26