Microvascular decompression for glossopharyngeal neuralgia. A personal 118 cases serie from Latin America. Glossopharyngeal neuralgia (GPN) is a craniofacial pain syndrome described as electrical discharges in the territory of the IX cranial nerve. A very rare neurovascular compression syndrome/cranial nerve HDS. Incidence 0.2–0.7/100,000 h/year. Misdiagnosis TN (V3). The MVD/MSD is a non-destructive technique focused on nerve isolation. Information about short and long-term efficacy of MVD for GPN is scarce. In our database, from 6 years 10 months we attended 2.248 diagnosis cases of HDS, 118 cases with some type of GPN, 40 simple and 78 combined type, and 34 underwent to MVD in our clinic. Results, we reach pain relief (88%), and poor result due to residual pain, not controlled with medication (5,9%); mortality rate cero. As an effective and safe procedure, minimally invasive MSD should be the first choice as a treatment for GPN, allowing good and excellent relief of glossopharyngeal neuropathic pain in most cases. Neurologia Segura Medical Center