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Purnima chaudhary 
Roll no.-77 
MBBS 2011
INTRODUCTION 
 Its now obvious that some known and unknown 
organism probably causes diarrhoea . 
 Regardless of the causative agents or age of patient; the 
sheet anchor of treatment is oral rehydration therapy 
such as the one advocated by WHO/ UNICEF.
DIARRHOEAL DISEASE CONTROL 
PROGRAMME 
The diarrhoel disease control programme was started in 1978 
 with the objective of reducing the mortality & morbidity 
due to diarrohoeal diseases. 
 from 1992-1993 , the programme has become a part of 
child survival & safe motherhood programme. 
 At present, it is a part of NRHM
COMPONENT OF A DIARRHOEAL 
DISEASES CONTROL PROGRAMME 
 Short Term 
Appropriate clinical management 
 Long Term 
. Better MCH care practices 
.preventive strategies 
.preventing diarrhoeal epidemics
Appropriate clinical 
management 
1. ORAL REHYDRATION THERAPY 
 The main aim of oral fluid therapy is to prevent 
dehydration and reduce mortality. 
 Oral fluid therapy is based on the observation that glucose 
given orally enhances the intestinal absorption of salt and 
water and is capable of correcting the electrolyte and water 
deficit.
 At 1st the composition of ORS ( oral rehydration salt ) 
recommended by WHO was sodium bicarbonate based 
INCLUSION OF TRISODIUM CITRATE IN PLACE OF 
SODIUM BICARBONATE 
 made product more stable 
 reduces stool output 
 increase intestinal absorption of sodium & water .
This ORS formulation focuses on reducing osmolarity of 
ORS solution; 
. to avoid adverse effects of hypertonicity on net fluid 
absorption by reducing concentration of glucose and 
sodium chloride in solution.
 Reduce the sodium concentration of ORS solution to 
75 mOsmol/ L ,improved the efficacy of ORS regimen 
for children with acute non-cholera diarhoea. 
 Since January 2004 new ORS formulation is the only 1 
procured by UNICEF . 
 INDIA was 1st country in world to launch ORS 
formulation since JUNE 2004
Composition of reduced osmolarity 
ORS 
REDUCED 
OSMOLALITY 
ORS 
GRAM/ 
LITRE 
SOD.CHLORIDE 2.6 
GLUCOSE, 
ANHYDROUS 
13.5 
POTASSIUM 
CHLORIDE 
1.5 
TRISODIUM 
CITRATE , 
DIHYDRATE 
2.9 
TOTAL WEIGHT 20.5 
REDUCED 
OSMOLARITY 
ORS 
Mmol/L 
SODIUM 75 
CHLORIDE 65 
GLUCOSE , 
75 
ANHYDROUS 
POTASSIUM 20 
CITRATE 10 
TOTAL 
OSMOLARITY 
245
How to access the dehydration 
MILD SEVERE 
PATIENT APPEARANCE THIRSTY, ALERT , 
RESTLESS 
DROWSY, LIMP, COLD 
,SWEATY, MAY BE 
COMATOSE . 
RADIAL PULSE NORMAL RATE & 
VOLUME 
RAPID , FEEBLE 
,SOMETIMES 
IMPALPABLE 
BLOOD PRESSURE NORMAL <80mm Hg 
SKIN ELASTICITY PINCH RETRACTS 
IMMEDIATELY 
PINCH RETRACTS VERY 
SLOWLY 
TONGUE MOIST VERY DRY 
URINE FLOW NORMAL LITTLE/ NONE 
ANTERIOR FONTANELLE NORMAL VERY SHRUKEN 
% BODY WEIGHT LOSS 4-5% 10% Or MORE
GUIDELINES FOR ORAL REHYDRATION THERAPY 
(FOR ALL AGES /DURING FIRST FOUR HOURS ) 
AGE Under 
4 
months 
4-11 
months 
1-2 yrs. 2-4 yrs. 5-14 yrs. 15 yrs. or 
over 
WEIGHT 
(KG) 
UNDER 
5 
5-7.9 2-10.9 11-15.9 16-29.9 30 OR 
OVER 
ORS 
SOLUTIO 
N ( IN ml) 
200- 
400 
400- 
600 
600- 
800 
800- 
1200 
1200- 
2200 
2200- 
4000 
Amt. of ORS sol.= wt. of child X 75 ml / kg
2. INTRAVENOUS REHYDRATION 
Intravenous infusion is usually required only for initial 
rehydration of severely dehydration pt. who is in 
shock or unable to drink . Such patients are best 
transferred to nearest hospital or treatment Centre . 
Solution recommended by WHO for intravenous 
infusion are……. 
1.RINGER LACTATION SOLUTION 
Its also known as Hartmamm’s solution for injection. It is the 
best commercially available solution . It supplies adequate 
concentration of sodium and potassium arid the lactate 
yields bicarbonate for correction of the acidosis.
2.DIARRHOEAL TREATMENT SOLUTION ( DTS ) 
 Recommended by WHO as ideal polyelectrolyte solution for 
intravenous infusion . It contains in one litre 
 Sodium Acetate- 6.5g, 
 Sodium Chloride- 4g, 
 Potassium Chloride- 1g 
 Glucose- 10g. 
 Normal saline can also be given but its poorest fluid because it 
will not correct the acidosis and will not replace the potassium 
losses. 
.
 Plain glucose and dextrose solution should not be used as 
they provide only water & glucose. 
 The initial rehydration should be fast until an easily palpable 
pulse is present . Reasses the patient every 1-2 hours. 
 After infusing 1-2 litres of fluid , rehydration should be 
carried out at a somewhat slower rate until pulse and blood 
pressure return to normal. 
 It is most helpful to examine skin elasticity and pulse 
strength ,both of which should be normal.
3.MAINTENANCE THERAPY 
 After the sign of dehydration has been corrected 
oral fluid should be used for maintenance therapy . 
AMOUNT OF 
DIARRHOEA 
AMOUNT OF ORAL 
FLUID 
Mild diarrhoea 
(not more than one stool every 
2hrs or longer, or less than 5ml 
stool per kg) 
100 ml /kg body weight per day 
until diarrhoea stops 
Severe diarrhoea 
(more than one stool every 2 
hours, or more than 5 ml of 
stool per kg per hour) 
Replace stool losses volume for 
volume , if not measurable give 
10-15 ml/kg body weight per 
hour
4 . APPROPRIATE FEEDING 
• Especially relevant for the exclusively breast-fed infants. If 
the child is breast-fed , nursing should be pursued during 
treatment with ORS solution. 
• Non-breast-fed infants under age 6 months should be given 
an additional 100-200 ml of clean water during the first four 
hour ,when old ORS containing 90 mmol/L is given. 
• But additional water is not given along with 75 mmol/L.
• Commercially carbonated beverages , commercial fruits 
& sweetened tea should not be given as it causes osmotic 
diarrhoea and hypernatraemia. 
• Rice water ,unsalted soup ,yoghurt drinks , green 
coconut water should be given.
5 . Chemotherapy 
• Drug of choice for cholera 
DOXICYCLINE 
TETRACYCLINE, 
TMP-SMX 
Drug of choice For diarrhoea due to shigella 
ciprofloxacin. 
As shigella resistant to ampicillin & TMP-SMX.
6 . ZINC SUPPLEMENT 
 It reduces episodes duration and severity so recommended 
by WHO & UNICEF 
 10 mg of Zn for infants under 6 months of age 20 mg 
for children older than 6 months for 10-14 days
B. BETTER MCH CARE 
PRACTICES . 
a . Maturation nutrition 
Improving prenatal nutrition will reduce the low birth weight 
problem 
Prenatal & postnatal nutrition will improve the quality of 
beast milk .
b. child nutrition 
. Promotion of Breast feeding 
. Appropriate weaning practices 
.Supplementary Feeding 
.vitamin A supplementation
C. PREVENTIVE STRATEGIES 
1 . SANITATION 
2 .HEALTH EDUCATION 
3 . IMMUNISATION 
4 . FLY CONTROL
Sanitation 
 It emphasis on personal & domestics hygiene like hand washing 
with soap before preparing food 
 before eating , 
 before feeding a child, 
 after defecation , 
 after cleaning a child who has defecated and 
 after disposing off a child’s stool .
Health Education 
 An important job of health worker is to prevent diarrhoea 
by convincing and helping community members to adopt 
and maintain preventive measures like breast feeding, 
 improved weaning , 
 clean drinking, 
 use of plenty of water for hygiene, 
 use of latrine, 
 proper disposal of stools of young children etc.
IMMUNISATION 
 Immunization against measles is a potential intervention 
for diarrhoea control. 
 Measles vaccine can prevent 25% of diarrhoeal deaths in 
children under 5 yrs. of age
ROTAVIRUS VACCINE 
There are two vaccines 
ROTARIX –TM ( monovalent human rotavirus vaccine) 
ROTA Teq-TM ( pentavelent bovine-human vaccine) 
Rotarix-TM …… 2 -dose schedule to 2 -4 months aged 
child 
1 . DOSE - 6 weeks - 12 weeks 
2 . DOSE - upto 16 weeks & no later than 24 
weeks. 
Rota Teq-TM……3 oral dose at ages 2,4,6 months.
FLY CONTROL 
 Flies breeding in association with human or 
animal faeces should be controlled.
Control and prevention of 
diarrhoeal epidemics 
An intersectoral approach centered upon PHC involving 
activities 
 in fields of water supply & excreta disposal ,communicable 
disease control, 
 mother & child health , 
 nutrition & health education is regarded as essential for 
ultimate for ultimate control of diarrhoeal diseases.
THANK U

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Diarrhoeal control programme

  • 1. Purnima chaudhary Roll no.-77 MBBS 2011
  • 2. INTRODUCTION  Its now obvious that some known and unknown organism probably causes diarrhoea .  Regardless of the causative agents or age of patient; the sheet anchor of treatment is oral rehydration therapy such as the one advocated by WHO/ UNICEF.
  • 3. DIARRHOEAL DISEASE CONTROL PROGRAMME The diarrhoel disease control programme was started in 1978  with the objective of reducing the mortality & morbidity due to diarrohoeal diseases.  from 1992-1993 , the programme has become a part of child survival & safe motherhood programme.  At present, it is a part of NRHM
  • 4. COMPONENT OF A DIARRHOEAL DISEASES CONTROL PROGRAMME  Short Term Appropriate clinical management  Long Term . Better MCH care practices .preventive strategies .preventing diarrhoeal epidemics
  • 5. Appropriate clinical management 1. ORAL REHYDRATION THERAPY  The main aim of oral fluid therapy is to prevent dehydration and reduce mortality.  Oral fluid therapy is based on the observation that glucose given orally enhances the intestinal absorption of salt and water and is capable of correcting the electrolyte and water deficit.
  • 6.  At 1st the composition of ORS ( oral rehydration salt ) recommended by WHO was sodium bicarbonate based INCLUSION OF TRISODIUM CITRATE IN PLACE OF SODIUM BICARBONATE  made product more stable  reduces stool output  increase intestinal absorption of sodium & water .
  • 7. This ORS formulation focuses on reducing osmolarity of ORS solution; . to avoid adverse effects of hypertonicity on net fluid absorption by reducing concentration of glucose and sodium chloride in solution.
  • 8.  Reduce the sodium concentration of ORS solution to 75 mOsmol/ L ,improved the efficacy of ORS regimen for children with acute non-cholera diarhoea.  Since January 2004 new ORS formulation is the only 1 procured by UNICEF .  INDIA was 1st country in world to launch ORS formulation since JUNE 2004
  • 9. Composition of reduced osmolarity ORS REDUCED OSMOLALITY ORS GRAM/ LITRE SOD.CHLORIDE 2.6 GLUCOSE, ANHYDROUS 13.5 POTASSIUM CHLORIDE 1.5 TRISODIUM CITRATE , DIHYDRATE 2.9 TOTAL WEIGHT 20.5 REDUCED OSMOLARITY ORS Mmol/L SODIUM 75 CHLORIDE 65 GLUCOSE , 75 ANHYDROUS POTASSIUM 20 CITRATE 10 TOTAL OSMOLARITY 245
  • 10. How to access the dehydration MILD SEVERE PATIENT APPEARANCE THIRSTY, ALERT , RESTLESS DROWSY, LIMP, COLD ,SWEATY, MAY BE COMATOSE . RADIAL PULSE NORMAL RATE & VOLUME RAPID , FEEBLE ,SOMETIMES IMPALPABLE BLOOD PRESSURE NORMAL <80mm Hg SKIN ELASTICITY PINCH RETRACTS IMMEDIATELY PINCH RETRACTS VERY SLOWLY TONGUE MOIST VERY DRY URINE FLOW NORMAL LITTLE/ NONE ANTERIOR FONTANELLE NORMAL VERY SHRUKEN % BODY WEIGHT LOSS 4-5% 10% Or MORE
  • 11. GUIDELINES FOR ORAL REHYDRATION THERAPY (FOR ALL AGES /DURING FIRST FOUR HOURS ) AGE Under 4 months 4-11 months 1-2 yrs. 2-4 yrs. 5-14 yrs. 15 yrs. or over WEIGHT (KG) UNDER 5 5-7.9 2-10.9 11-15.9 16-29.9 30 OR OVER ORS SOLUTIO N ( IN ml) 200- 400 400- 600 600- 800 800- 1200 1200- 2200 2200- 4000 Amt. of ORS sol.= wt. of child X 75 ml / kg
  • 12. 2. INTRAVENOUS REHYDRATION Intravenous infusion is usually required only for initial rehydration of severely dehydration pt. who is in shock or unable to drink . Such patients are best transferred to nearest hospital or treatment Centre . Solution recommended by WHO for intravenous infusion are……. 1.RINGER LACTATION SOLUTION Its also known as Hartmamm’s solution for injection. It is the best commercially available solution . It supplies adequate concentration of sodium and potassium arid the lactate yields bicarbonate for correction of the acidosis.
  • 13. 2.DIARRHOEAL TREATMENT SOLUTION ( DTS )  Recommended by WHO as ideal polyelectrolyte solution for intravenous infusion . It contains in one litre  Sodium Acetate- 6.5g,  Sodium Chloride- 4g,  Potassium Chloride- 1g  Glucose- 10g.  Normal saline can also be given but its poorest fluid because it will not correct the acidosis and will not replace the potassium losses. .
  • 14.  Plain glucose and dextrose solution should not be used as they provide only water & glucose.  The initial rehydration should be fast until an easily palpable pulse is present . Reasses the patient every 1-2 hours.  After infusing 1-2 litres of fluid , rehydration should be carried out at a somewhat slower rate until pulse and blood pressure return to normal.  It is most helpful to examine skin elasticity and pulse strength ,both of which should be normal.
  • 15. 3.MAINTENANCE THERAPY  After the sign of dehydration has been corrected oral fluid should be used for maintenance therapy . AMOUNT OF DIARRHOEA AMOUNT OF ORAL FLUID Mild diarrhoea (not more than one stool every 2hrs or longer, or less than 5ml stool per kg) 100 ml /kg body weight per day until diarrhoea stops Severe diarrhoea (more than one stool every 2 hours, or more than 5 ml of stool per kg per hour) Replace stool losses volume for volume , if not measurable give 10-15 ml/kg body weight per hour
  • 16. 4 . APPROPRIATE FEEDING • Especially relevant for the exclusively breast-fed infants. If the child is breast-fed , nursing should be pursued during treatment with ORS solution. • Non-breast-fed infants under age 6 months should be given an additional 100-200 ml of clean water during the first four hour ,when old ORS containing 90 mmol/L is given. • But additional water is not given along with 75 mmol/L.
  • 17. • Commercially carbonated beverages , commercial fruits & sweetened tea should not be given as it causes osmotic diarrhoea and hypernatraemia. • Rice water ,unsalted soup ,yoghurt drinks , green coconut water should be given.
  • 18. 5 . Chemotherapy • Drug of choice for cholera DOXICYCLINE TETRACYCLINE, TMP-SMX Drug of choice For diarrhoea due to shigella ciprofloxacin. As shigella resistant to ampicillin & TMP-SMX.
  • 19. 6 . ZINC SUPPLEMENT  It reduces episodes duration and severity so recommended by WHO & UNICEF  10 mg of Zn for infants under 6 months of age 20 mg for children older than 6 months for 10-14 days
  • 20. B. BETTER MCH CARE PRACTICES . a . Maturation nutrition Improving prenatal nutrition will reduce the low birth weight problem Prenatal & postnatal nutrition will improve the quality of beast milk .
  • 21. b. child nutrition . Promotion of Breast feeding . Appropriate weaning practices .Supplementary Feeding .vitamin A supplementation
  • 22. C. PREVENTIVE STRATEGIES 1 . SANITATION 2 .HEALTH EDUCATION 3 . IMMUNISATION 4 . FLY CONTROL
  • 23. Sanitation  It emphasis on personal & domestics hygiene like hand washing with soap before preparing food  before eating ,  before feeding a child,  after defecation ,  after cleaning a child who has defecated and  after disposing off a child’s stool .
  • 24. Health Education  An important job of health worker is to prevent diarrhoea by convincing and helping community members to adopt and maintain preventive measures like breast feeding,  improved weaning ,  clean drinking,  use of plenty of water for hygiene,  use of latrine,  proper disposal of stools of young children etc.
  • 25. IMMUNISATION  Immunization against measles is a potential intervention for diarrhoea control.  Measles vaccine can prevent 25% of diarrhoeal deaths in children under 5 yrs. of age
  • 26. ROTAVIRUS VACCINE There are two vaccines ROTARIX –TM ( monovalent human rotavirus vaccine) ROTA Teq-TM ( pentavelent bovine-human vaccine) Rotarix-TM …… 2 -dose schedule to 2 -4 months aged child 1 . DOSE - 6 weeks - 12 weeks 2 . DOSE - upto 16 weeks & no later than 24 weeks. Rota Teq-TM……3 oral dose at ages 2,4,6 months.
  • 27. FLY CONTROL  Flies breeding in association with human or animal faeces should be controlled.
  • 28. Control and prevention of diarrhoeal epidemics An intersectoral approach centered upon PHC involving activities  in fields of water supply & excreta disposal ,communicable disease control,  mother & child health ,  nutrition & health education is regarded as essential for ultimate for ultimate control of diarrhoeal diseases.