SlideShare a Scribd company logo

Drug Abuse PPT by nirav

•Download as PPT, PDF•
•
N
niravkd

addiction and abuse

Education
1 of 77
Drug abuse and addiction 14-times Olympic gold medal winner Michael Phelps caught with cannabis pipe
Confusion in definition !!! ,[object Object],[object Object],[object Object],[object Object],[object Object]
American Psychiatric Association 's Diagnostic and Statistical Manual of Mental Disorders (DSM) ,[object Object],[object Object]
Substance Dependence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pharmacology behind addiction - reinforcement ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THE MESOLIMBIC DOPAMINERGIC REWARD PATHWAY
 
Animal models
Animal models ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Dopamine Hypothesis of Addiction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TOLERANCE ,[object Object],[object Object],[object Object],[object Object]
Acquired tolerance ,[object Object],[object Object],[object Object],[object Object]
Acquired tolerance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acquired tolerance ,[object Object],[object Object],[object Object],[object Object]
Acquired tolerance ,[object Object],[object Object],[object Object],[object Object]
Physical dependence ,[object Object],[object Object],[object Object],[object Object]
Withdrawal Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object]
Psychological dependence ,[object Object],[object Object],[object Object]
Classification of drugs of abuse ,[object Object],[object Object],[object Object]
Drugs that activate GPCR Partial agonist 5-HT 2A R LSD, mescaline disinhibition Weak agonist GABA b R Gamma- hydroxybutyric acid(GHB) disinhibition agonist CB1R Cannabinoids disinhibition agonist μ - OR Opiods Effect on DA neurons Action Molecular target drugs
Drugs that bind to ionotrophic receptor and ion channels Effect on DA neurons Action Molecular target drugs - antagonists NMDA Phencyclidine, ketamine disinhibition Positive modulator GABA A Benzodiazepines Excitement, disinhibition? GABA A ,5-HT3, nACh, NMDA Alcohol Excitement, disinhibition? Agonist nAChR Nicotine
Drugs that bind to transporter of biogenic amines Effect on DA neurons Action Molecular target drugs Blocks DA uptake Reverses transport SERT>DAT, NET Ecstasy Blocks DA uptake Reverses transport DAT,SERT, NET,VMAT Amphetamine Blocks DA uptake Inhibitor DAT,SERT, NET Cocaine
[object Object],[object Object],[object Object],[object Object]
Opioids – God's own medicine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Heroin- most commonly abused opiate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tolerance – opioids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Physical dependence and withdrawal syndrome - opioids Yawning ,fever Dysphoric mood, craving for drug Tachycardia Anxiety Gooseflesh Insomnia Sweating Irritability Mydriasis Restlessness signs symptoms
Rx of withdrawal syndrome ,[object Object],[object Object],[object Object],[object Object]
Rx of opioid addiction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
CANNABINOIDS ,[object Object],[object Object],[object Object]
CANNABINOIDS – ganja- marijuana-hashish- charas ,[object Object],[object Object],[object Object],[object Object]
Common Routes- CANNABINOIDS ,[object Object],[object Object],[object Object],[object Object]
actions - cannabis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tolerance ,depenadence, withdrawal ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx of cannabis addiction ,[object Object],[object Object]
GAMMA-HYDROXYBUTYRIC ACID (GHB) ,[object Object],[object Object],[object Object],[object Object],[object Object]
GHB – liquid ecstasy - club drug ,[object Object],[object Object],[object Object],[object Object]
LSD, MESCALINE & PSILOCYBIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LSD, MESCALINE & PSILOCYBIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
nicotine ,[object Object],[object Object],[object Object],[object Object],[object Object]
nicotine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tolerance ,dependence, withdrawal -nicotine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx of nicotine addiction ,[object Object],[object Object],[object Object],[object Object],[object Object]
Rx of nicotine addiction ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
ethanol ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
William Shakespeare and action of ethanol in MACBETH ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Chronic alcohol abuse = alcoholism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
alcoholism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tolerance , dependence, withdrawal - alcohol abuse ,[object Object],[object Object],[object Object],[object Object]
Alcohol withdrawal syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx of withdrawal syndrome - alcoholism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx of alcoholism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BENZODIAZEPINES (BZDs) ,[object Object],[object Object],[object Object],[object Object]
BZDs ,[object Object],[object Object],[object Object],[object Object],[object Object]
Benzodiazepine withdrawal ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx of BZDs addiction ,[object Object],[object Object],[object Object],[object Object],[object Object]
KETAMINE & PHENCYCLIDINE (PCP) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
KETAMINE & PHENCYCLIDINE (PCP) ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
cocaine ,[object Object],[object Object],[object Object],[object Object]
 
cocaine ,[object Object],[object Object],[object Object]
Effects of cocaine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Speedball ,[object Object],[object Object],[object Object],[object Object]
Tolerance ,dependence, withdrawal - cocaine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Rx of cocaine addiction ,[object Object],[object Object],[object Object],[object Object],[object Object]
AMPHETAMINE ,[object Object],[object Object],[object Object],[object Object]
AMPHETAMINE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MDMA = ecstasy ,[object Object],[object Object],[object Object]
MDMA = ecstasy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
references ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]

Recommended

Drugs Of Abuse
Drugs Of AbuseDrugs Of Abuse
Drugs Of Abuse
Rathnakar U P
 
Cns stimulants
Cns stimulantsCns stimulants
Cns stimulants
vikasaagrahari007
 
Hallucinogens pharmacology
Hallucinogens pharmacologyHallucinogens pharmacology
Hallucinogens pharmacology
Koppala RVS Chaitanya
 
Cns stimulants & drugs of abuse
Cns stimulants & drugs of abuseCns stimulants & drugs of abuse
Cns stimulants & drugs of abuse
Ashfaq Ahmad
 
Marijuana Abuse - Information
Marijuana Abuse - InformationMarijuana Abuse - Information
Marijuana Abuse - Information
University of Johannesburg
 
Drug Addictions
Drug AddictionsDrug Addictions
Drug Addictions
guestc3c278
 
stimulants
stimulantsstimulants
stimulants
Ikenna Godwin
 
Pharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic DrugsPharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic Drugs
shabeel pn
 

Recommended

Drugs Of Abuse
Drugs Of AbuseDrugs Of Abuse
Drugs Of Abuse
Rathnakar U P
 
Cns stimulants
Cns stimulantsCns stimulants
Cns stimulants
vikasaagrahari007
 
Hallucinogens pharmacology
Hallucinogens pharmacologyHallucinogens pharmacology
Hallucinogens pharmacology
Koppala RVS Chaitanya
 
Cns stimulants & drugs of abuse
Cns stimulants & drugs of abuseCns stimulants & drugs of abuse
Cns stimulants & drugs of abuse
Ashfaq Ahmad
 
Marijuana Abuse - Information
Marijuana Abuse - InformationMarijuana Abuse - Information
Marijuana Abuse - Information
University of Johannesburg
 
Drug Addictions
Drug AddictionsDrug Addictions
Drug Addictions
guestc3c278
 
stimulants
stimulantsstimulants
stimulants
Ikenna Godwin
 
Pharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic DrugsPharmacology of Antiepileptic Drugs
Pharmacology of Antiepileptic Drugs
shabeel pn
 
Amphetamine.final.pptx
Amphetamine.final.pptxAmphetamine.final.pptx
Amphetamine.final.pptx
Obydulla (Al Mamun)
 
hallucinogens
hallucinogenshallucinogens
hallucinogens
Ikenna Godwin
 
Hallucinogens
HallucinogensHallucinogens
Hallucinogens
Michelle Meyer
 
Drugs of abuse - Pharmacology
Drugs of abuse - PharmacologyDrugs of abuse - Pharmacology
Drugs of abuse - Pharmacology
Areej Abu Hanieh
 
Amphetamine
AmphetamineAmphetamine
Amphetamine
Angel Yoanna
 
Drug dependence and drug abuse
Drug dependence and drug abuseDrug dependence and drug abuse
Drug dependence and drug abuse
Fred Ecaldre
 
Stimulants
Stimulants Stimulants
Stimulants
shabeel pn
 
Pharmacotherapy of schizophrenia
Pharmacotherapy of schizophreniaPharmacotherapy of schizophrenia
Pharmacotherapy of schizophrenia
Prasheeta V P
 
Amphetamine and ecstasy
Amphetamine and ecstasyAmphetamine and ecstasy
Amphetamine and ecstasy
sara_abudahab
 
Anxiety Pharmacology
Anxiety PharmacologyAnxiety Pharmacology
Anxiety Pharmacology
Jaineel Dharod
 
Hallucinogenic drugs
Hallucinogenic drugsHallucinogenic drugs
Hallucinogenic drugs
faculty of Pharmacy
 
Stimulants PowerPoint
Stimulants PowerPoint Stimulants PowerPoint
Stimulants PowerPoint
bridgettebazin
 
Cns stimulants & cognition enhancers
Cns stimulants & cognition enhancersCns stimulants & cognition enhancers
Cns stimulants & cognition enhancers
Rudhra Prabhakar
 
Neurohumoral transmission in CNS
Neurohumoral transmission in CNSNeurohumoral transmission in CNS
Neurohumoral transmission in CNS
Sanchit Dhankhar
 
Drug therapy of depression
Drug therapy of depression Drug therapy of depression
Drug therapy of depression
Dr Htet
 
Chapter 6 Cocaine, Amphetamines, And Related Stimulants
Chapter 6 Cocaine, Amphetamines, And Related StimulantsChapter 6 Cocaine, Amphetamines, And Related Stimulants
Chapter 6 Cocaine, Amphetamines, And Related Stimulants
Justin Gatewood
 
Antianxiety drugs pharmacology
Antianxiety drugs pharmacologyAntianxiety drugs pharmacology
Antianxiety drugs pharmacology
PranatiChavan
 
Drug abuse
Drug abuseDrug abuse
Drug abuse
Samuel Trinity
 
Drug dependence & Drug Abuse
Drug dependence & Drug AbuseDrug dependence & Drug Abuse
Drug dependence & Drug Abuse
Mahi Yeruva
 
Nootropics (M.Pharm)
Nootropics (M.Pharm)Nootropics (M.Pharm)
Nootropics (M.Pharm)
Ravindra Saroj
 
Drug abuse
Drug abuseDrug abuse
Drug abuse
Karthiga M
 
Pinel basics ch13
Pinel basics ch13Pinel basics ch13
Pinel basics ch13
professorbent
 

More Related Content

What's hot

Drug dependence and drug abuse
Drug dependence and drug abuseDrug dependence and drug abuse
Drug dependence and drug abuse
Fred Ecaldre
 
Stimulants PowerPoint
Stimulants PowerPoint Stimulants PowerPoint
Stimulants PowerPoint
bridgettebazin
 
Chapter 6 Cocaine, Amphetamines, And Related Stimulants
Chapter 6 Cocaine, Amphetamines, And Related StimulantsChapter 6 Cocaine, Amphetamines, And Related Stimulants
Chapter 6 Cocaine, Amphetamines, And Related Stimulants
Justin Gatewood
 

What's hot (20)

Amphetamine.final.pptx
Amphetamine.final.pptxAmphetamine.final.pptx
Amphetamine.final.pptx
 
hallucinogens
hallucinogenshallucinogens
hallucinogens
 
Hallucinogens
HallucinogensHallucinogens
Hallucinogens
 
Drugs of abuse - Pharmacology
Drugs of abuse - PharmacologyDrugs of abuse - Pharmacology
Drugs of abuse - Pharmacology
 
Amphetamine
AmphetamineAmphetamine
Amphetamine
 
Drug dependence and drug abuse
Drug dependence and drug abuseDrug dependence and drug abuse
Drug dependence and drug abuse
 
Stimulants
Stimulants Stimulants
Stimulants
 
Pharmacotherapy of schizophrenia
Pharmacotherapy of schizophreniaPharmacotherapy of schizophrenia
Pharmacotherapy of schizophrenia
 
Amphetamine and ecstasy
Amphetamine and ecstasyAmphetamine and ecstasy
Amphetamine and ecstasy
 
Anxiety Pharmacology
Anxiety PharmacologyAnxiety Pharmacology
Anxiety Pharmacology
 
Hallucinogenic drugs
Hallucinogenic drugsHallucinogenic drugs
Hallucinogenic drugs
 
Stimulants PowerPoint
Stimulants PowerPoint Stimulants PowerPoint
Stimulants PowerPoint
 
Cns stimulants & cognition enhancers
Cns stimulants & cognition enhancersCns stimulants & cognition enhancers
Cns stimulants & cognition enhancers
 
Neurohumoral transmission in CNS
Neurohumoral transmission in CNSNeurohumoral transmission in CNS
Neurohumoral transmission in CNS
 
Drug therapy of depression
Drug therapy of depression Drug therapy of depression
Drug therapy of depression
 
Chapter 6 Cocaine, Amphetamines, And Related Stimulants
Chapter 6 Cocaine, Amphetamines, And Related StimulantsChapter 6 Cocaine, Amphetamines, And Related Stimulants
Chapter 6 Cocaine, Amphetamines, And Related Stimulants
 
Antianxiety drugs pharmacology
Antianxiety drugs pharmacologyAntianxiety drugs pharmacology
Antianxiety drugs pharmacology
 
Drug abuse
Drug abuseDrug abuse
Drug abuse
 
Drug dependence & Drug Abuse
Drug dependence & Drug AbuseDrug dependence & Drug Abuse
Drug dependence & Drug Abuse
 
Nootropics (M.Pharm)
Nootropics (M.Pharm)Nootropics (M.Pharm)
Nootropics (M.Pharm)
 

Similar to Drug Abuse PPT by nirav

Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Deepthi P Ramachandran
 
Chapter 5 Psychopharmacology And New Drug Development
Chapter 5 Psychopharmacology And New Drug DevelopmentChapter 5 Psychopharmacology And New Drug Development
Chapter 5 Psychopharmacology And New Drug Development
Justin Gatewood
 
PSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdf
PSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdfPSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdf
PSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdf
EugenMweemba
 

Similar to Drug Abuse PPT by nirav (20)

Drug abuse
Drug abuseDrug abuse
Drug abuse
 
Pinel basics ch13
Pinel basics ch13Pinel basics ch13
Pinel basics ch13
 
Homeopathic Doctor - Dr. Anita Salunke homeopathic clinic for Drug Addiction ...
Homeopathic Doctor - Dr. Anita Salunke homeopathic clinic for Drug Addiction ...Homeopathic Doctor - Dr. Anita Salunke homeopathic clinic for Drug Addiction ...
Homeopathic Doctor - Dr. Anita Salunke homeopathic clinic for Drug Addiction ...
 
Effective treatment for drug addiction in Mindheal Homeopathy clinic ,Chembur...
Effective treatment for drug addiction in Mindheal Homeopathy clinic ,Chembur...Effective treatment for drug addiction in Mindheal Homeopathy clinic ,Chembur...
Effective treatment for drug addiction in Mindheal Homeopathy clinic ,Chembur...
 
Psychiatric drugs of abuse
Psychiatric drugs of abusePsychiatric drugs of abuse
Psychiatric drugs of abuse
 
Drug dependence
Drug dependenceDrug dependence
Drug dependence
 
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
Drug detoxication, Tolerance, Intolerance, Combined effects, Dosage, Classifi...
 
Neuropsychopharmacology
NeuropsychopharmacologyNeuropsychopharmacology
Neuropsychopharmacology
 
Chapter 5 Psychopharmacology And New Drug Development
Chapter 5 Psychopharmacology And New Drug DevelopmentChapter 5 Psychopharmacology And New Drug Development
Chapter 5 Psychopharmacology And New Drug Development
 
Drug Addiction Pharmainfo
Drug Addiction PharmainfoDrug Addiction Pharmainfo
Drug Addiction Pharmainfo
 
Dependence
DependenceDependence
Dependence
 
Factors modifying drug action
Factors modifying drug actionFactors modifying drug action
Factors modifying drug action
 
IVMS-CNS Pharmacology- Intro to Drugs of Abuse II-Opioids
IVMS-CNS Pharmacology- Intro to Drugs of Abuse II-OpioidsIVMS-CNS Pharmacology- Intro to Drugs of Abuse II-Opioids
IVMS-CNS Pharmacology- Intro to Drugs of Abuse II-Opioids
 
Substance abuse - Signs and Symptoms & Treatment over dependence CLINICAL TOX...
Substance abuse - Signs and Symptoms & Treatment over dependence CLINICAL TOX...Substance abuse - Signs and Symptoms & Treatment over dependence CLINICAL TOX...
Substance abuse - Signs and Symptoms & Treatment over dependence CLINICAL TOX...
 
Pharmacodynamics part 4
Pharmacodynamics part 4Pharmacodynamics part 4
Pharmacodynamics part 4
 
Drug addiction
Drug addictionDrug addiction
Drug addiction
 
substance dependance.pptx
substance dependance.pptxsubstance dependance.pptx
substance dependance.pptx
 
PSYCHOTROPIC DRUGS, DRUG ABUSE & DRUG DEPENDENCE.pptx
PSYCHOTROPIC DRUGS, DRUG ABUSE & DRUG DEPENDENCE.pptxPSYCHOTROPIC DRUGS, DRUG ABUSE & DRUG DEPENDENCE.pptx
PSYCHOTROPIC DRUGS, DRUG ABUSE & DRUG DEPENDENCE.pptx
 
Mechanism of habituation
Mechanism of habituationMechanism of habituation
Mechanism of habituation
 
PSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdf
PSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdfPSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdf
PSYCHOTROPIC DRUGS, DRUG ABUSE DRUG DEPENDENCE - FINAL (1).pdf
 

Recently uploaded

The basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptxThe basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptx
heathfieldcps1
 
Salient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functionsSalient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functions
KarakKing
 

Recently uploaded (20)

Kodo Millet PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...
Kodo Millet PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...Kodo Millet PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...
Kodo Millet PPT made by Ghanshyam bairwa college of Agriculture kumher bhara...
 
Towards a code of practice for AI in AT.pptx
Towards a code of practice for AI in AT.pptxTowards a code of practice for AI in AT.pptx
Towards a code of practice for AI in AT.pptx
 
2024-NATIONAL-LEARNING-CAMP-AND-OTHER.pptx
2024-NATIONAL-LEARNING-CAMP-AND-OTHER.pptx2024-NATIONAL-LEARNING-CAMP-AND-OTHER.pptx
2024-NATIONAL-LEARNING-CAMP-AND-OTHER.pptx
 
ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.
 
HMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptx
HMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptxHMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptx
HMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptx
 
Wellbeing inclusion and digital dystopias.pptx
Wellbeing inclusion and digital dystopias.pptxWellbeing inclusion and digital dystopias.pptx
Wellbeing inclusion and digital dystopias.pptx
 
Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024
 
Python Notes for mca i year students osmania university.docx
Python Notes for mca i year students osmania university.docxPython Notes for mca i year students osmania university.docx
Python Notes for mca i year students osmania university.docx
 
How to setup Pycharm environment for Odoo 17.pptx
How to setup Pycharm environment for Odoo 17.pptxHow to setup Pycharm environment for Odoo 17.pptx
How to setup Pycharm environment for Odoo 17.pptx
 
On National Teacher Day, meet the 2024-25 Kenan Fellows
On National Teacher Day, meet the 2024-25 Kenan FellowsOn National Teacher Day, meet the 2024-25 Kenan Fellows
On National Teacher Day, meet the 2024-25 Kenan Fellows
 
Understanding Accommodations and Modifications
Understanding Accommodations and ModificationsUnderstanding Accommodations and Modifications
Understanding Accommodations and Modifications
 
The basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptxThe basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptx
 
HMCS Max Bernays Pre-Deployment Brief (May 2024).pptx
HMCS Max Bernays Pre-Deployment Brief (May 2024).pptxHMCS Max Bernays Pre-Deployment Brief (May 2024).pptx
HMCS Max Bernays Pre-Deployment Brief (May 2024).pptx
 
How to Give a Domain for a Field in Odoo 17
How to Give a Domain for a Field in Odoo 17How to Give a Domain for a Field in Odoo 17
How to Give a Domain for a Field in Odoo 17
 
Salient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functionsSalient Features of India constitution especially power and functions
Salient Features of India constitution especially power and functions
 
Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...
Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...
Sensory_Experience_and_Emotional_Resonance_in_Gabriel_Okaras_The_Piano_and_Th...
 
Key note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfKey note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdf
 
Micro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdfMicro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdf
 
REMIFENTANIL: An Ultra short acting opioid.pptx
REMIFENTANIL: An Ultra short acting opioid.pptxREMIFENTANIL: An Ultra short acting opioid.pptx
REMIFENTANIL: An Ultra short acting opioid.pptx
 
Jamworks pilot and AI at Jisc (20/03/2024)
Jamworks pilot and AI at Jisc (20/03/2024)Jamworks pilot and AI at Jisc (20/03/2024)
Jamworks pilot and AI at Jisc (20/03/2024)
 

Drug Abuse PPT by nirav

  • 1. Drug abuse and addiction 14-times Olympic gold medal winner Michael Phelps caught with cannabis pipe
  • 2.
  • 3.
  • 4.
  • 5.
  • 7.  
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20. Drugs that activate GPCR Partial agonist 5-HT 2A R LSD, mescaline disinhibition Weak agonist GABA b R Gamma- hydroxybutyric acid(GHB) disinhibition agonist CB1R Cannabinoids disinhibition agonist μ - OR Opiods Effect on DA neurons Action Molecular target drugs
  • 21. Drugs that bind to ionotrophic receptor and ion channels Effect on DA neurons Action Molecular target drugs - antagonists NMDA Phencyclidine, ketamine disinhibition Positive modulator GABA A Benzodiazepines Excitement, disinhibition? GABA A ,5-HT3, nACh, NMDA Alcohol Excitement, disinhibition? Agonist nAChR Nicotine
  • 22. Drugs that bind to transporter of biogenic amines Effect on DA neurons Action Molecular target drugs Blocks DA uptake Reverses transport SERT>DAT, NET Ecstasy Blocks DA uptake Reverses transport DAT,SERT, NET,VMAT Amphetamine Blocks DA uptake Inhibitor DAT,SERT, NET Cocaine
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28. Physical dependence and withdrawal syndrome - opioids Yawning ,fever Dysphoric mood, craving for drug Tachycardia Anxiety Gooseflesh Insomnia Sweating Irritability Mydriasis Restlessness signs symptoms
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.
  • 51.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.
  • 61.
  • 62.
  • 63.
  • 64.
  • 65.
  • 66.  
  • 67.
  • 68.
  • 69.
  • 70.
  • 71.
  • 72.
  • 73.
  • 74.
  • 75.
  • 76.
  • 77.