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INTRODUCING
OUR NEW
PRODUCT

 SYSMEX XE 5000
A BRIEF INTRODUCTION
   The Sysmex XE-5000 Automated Hematology System utilizes the
   power of fluorescent flow cytometry and hydrodynamic focusing
   technologies.




   Using a unique and advanced diode laser bench, Sysmex fluorescent
   flow cytometry provides the sensitivity needed for measuring and
   differentiating cell types in whole blood and body fluid samples.



   Fluorescent technology and hydrodynamic focusing enable the XE-
   5000 to consistently differentiate normal WBC, RBC and PLT
   populations from abnormal populations, thereby decreasing the
   number of manual interventions.



   The XE-5000 technology provides clinically relevant and reportable
   parameters.
Reportable parameters

 43 parameters
•CBC (14 parameters)
 –WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, MPV, P-
   LCR, PDW, PCT
•DIFF (12 parameters)
–
NEUT%, LYMPH%, MONO%, EO%, BASO%, IG%, NEUT#, LYMPH#, MONO#,
EO#, BASO#, IG#
•NRBC (2 parameters)
–NRBC%, NRBC#,
•RET (8 Parameters)
–RET%, RET#, LFR, MFR, HFR, IRF, RET-He, IPF, (PLT-O)
•Body Fluid (6 parameters)
–WBC-BF, RBC-BF, MN%, MN#, PMN%, PMN#
-HPC
SPECIFICATIONS
Principles & Technologies   Fluorescent Flow Cytometry:
                            WBC-Diff, IG, NRBC, RET, IRF, PLT-O
                            RF-DC method:
                            HPC
                            DC-Sheath-Flow:
                            PLT, RBC, HCT
                            SLS-Method:
                            Hgb
Linearity                   WBC: 0 – 440.00 x 103
                            /µL
                            RBC: 0 – 8.00 x 106
                            /µL
                            PLT: 0 – 5,000 x 103
                            /µL
Body Fluid Linearity        WBC-BF: 0.000 – 10.000 x 103
                            /µL
                            TC-BF: 0.000 – 10.000 x 103
                            /µL
                            RBC-BF: 0.000 – 5.000 x 106
                            /µL
SPECIFICATIONS
Throughput                           Whole Blood Mode:
                                     150 samples/hr (max.)
                                     Body Fluid Mode:
                                     38 samples/hr (max.)
Sample Volumes                       200μL / 130μL (manual closed
                                     mode/open mode)
                                     40μL for capillary mode

Data Storage                         10,000 samples (incl. graphics)
(IPU: Information Processing Unit)


Interfaces                           Sysmex WAM (HL7 & ASTM)
SPECIFICATIONS
Quality Control (Total QC Management)   Levey-Jennings control chart
                                        X-bar M file
                                        Online QC


Dimensions / Weight                     Main unit: 27.8" x 35.9" x 28" / 178 lbs.
w x h x d [in] / [lbs]                  Sampler: 22.8" x 7.7" x 14.8" / 26 lbs.
                                        IPU: 18" x 17.6" x 5.3" / 24 lbs.

Configurations                           Stand alone
                                        Sysmex HST-N™, Sysmex XE-AlphaN™
TARGET CUSTOMER

 SUITABLE FOR LAB WHICH RECEIVES
  GREATER NUMBER OF SAMPLES PER DAY
 SUITABLE FOR LAB WITH LESS STAFFS AS
  OUR ANALYZER IS AUTOMATED AND
  REQUIRES LESS MANPOWER.
XE-5000 ANALYSIS PRINCIPLE

 •Laser Flow Cytometry
 •ShealthFlow/Hydrodynamic Focusing DC
  detection
 •RF/DC Detection Method
 •SLS Heamoglobin Method
FLUOROSCENCE FLOW CYTOMETRY
DC-HYDRODYNAMIC FOCUSING
XE-5OO0 MULTICHANNEL ANALYZER
 CHANNEL            PRINCIPLE          PARAMETERS
 WBC/BASO           Flow cytometry     WBC,Baso #, Baso
 NRBC               Flow cytometry     NRBC #, NRBC %
 4 Diff             Flow cytomtery     Lymph# , Lymph%
                                       Mono#, Mono%
                                       Eo# , Eo%
                                       Neut# , Neut%
                                       IG# , IG%
 RET/PLT-O          Flow cytometry     RET#, RET%,PLT-O,
                                       HFR, MFR, LFR, IRF
                                       RET-He, IPF
 IMI                RF/DC-detection    HPC#
                    method
 HGB                SLS-Method,        HGB
                    photometry         MCH,MCHC,MCV
 RBC/PLT-Detector   HDF DC-Detection   RBC,HCT,PLT-I,RDW-
                    method             SD, RDW-CV, PDW,
                                       MPV, P-LCR
REAGENT SYSTEM
OUTPUT
WHY SYSMEX XE-5000??

 Integrated Sysmex SP-Series automated
  slide maker/stainer.
 eMM software provides more specific
  flagging.
 Measure body fluids.
 Advanced parameters
WHY SYSMEX XE-5000 ?

• HIGH THROUGHOUTPUT
• NO NEED OF SAMPLE PREPARATION
• SHORTENED TURN AROUND TIME
• REDUCED SAMPLE VOLUME
• LESS LIKEHOOD OF TRANSCRIPTIONAL ERRORS
• PROVIDES 7 SCATTERGRAMS AND 2
  HISTOGRAM FOR A BETTER ANALYSIS
 RANKED BY THIRD PARTY AS HIGHEST VENDOR
  FOR RELIABILITY FOR 8 CONSECUTIVE YEARS IN
  A ROW*
CUSTOMER SERVICE

• In-time deliveries of reagents and
    consumable
•   Instrument repair and maintenance including
    hot-line support
•   Consultancy and management of complex
    laboratory installation projects
•   Continuous post-market surveillance and
    feedback of market requirements as design
    input for new product development
•   Management of customer events
Sysmex xe-5000

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Sysmex xe-5000

  • 2. A BRIEF INTRODUCTION The Sysmex XE-5000 Automated Hematology System utilizes the power of fluorescent flow cytometry and hydrodynamic focusing technologies. Using a unique and advanced diode laser bench, Sysmex fluorescent flow cytometry provides the sensitivity needed for measuring and differentiating cell types in whole blood and body fluid samples. Fluorescent technology and hydrodynamic focusing enable the XE- 5000 to consistently differentiate normal WBC, RBC and PLT populations from abnormal populations, thereby decreasing the number of manual interventions. The XE-5000 technology provides clinically relevant and reportable parameters.
  • 3. Reportable parameters  43 parameters •CBC (14 parameters)  –WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, MPV, P- LCR, PDW, PCT •DIFF (12 parameters) – NEUT%, LYMPH%, MONO%, EO%, BASO%, IG%, NEUT#, LYMPH#, MONO#, EO#, BASO#, IG# •NRBC (2 parameters) –NRBC%, NRBC#, •RET (8 Parameters) –RET%, RET#, LFR, MFR, HFR, IRF, RET-He, IPF, (PLT-O) •Body Fluid (6 parameters) –WBC-BF, RBC-BF, MN%, MN#, PMN%, PMN# -HPC
  • 4. SPECIFICATIONS Principles & Technologies Fluorescent Flow Cytometry: WBC-Diff, IG, NRBC, RET, IRF, PLT-O RF-DC method: HPC DC-Sheath-Flow: PLT, RBC, HCT SLS-Method: Hgb Linearity WBC: 0 – 440.00 x 103 /µL RBC: 0 – 8.00 x 106 /µL PLT: 0 – 5,000 x 103 /µL Body Fluid Linearity WBC-BF: 0.000 – 10.000 x 103 /µL TC-BF: 0.000 – 10.000 x 103 /µL RBC-BF: 0.000 – 5.000 x 106 /µL
  • 5. SPECIFICATIONS Throughput Whole Blood Mode: 150 samples/hr (max.) Body Fluid Mode: 38 samples/hr (max.) Sample Volumes 200μL / 130μL (manual closed mode/open mode) 40μL for capillary mode Data Storage 10,000 samples (incl. graphics) (IPU: Information Processing Unit) Interfaces Sysmex WAM (HL7 & ASTM)
  • 6. SPECIFICATIONS Quality Control (Total QC Management) Levey-Jennings control chart X-bar M file Online QC Dimensions / Weight Main unit: 27.8" x 35.9" x 28" / 178 lbs. w x h x d [in] / [lbs] Sampler: 22.8" x 7.7" x 14.8" / 26 lbs. IPU: 18" x 17.6" x 5.3" / 24 lbs. Configurations Stand alone Sysmex HST-N™, Sysmex XE-AlphaN™
  • 7. TARGET CUSTOMER  SUITABLE FOR LAB WHICH RECEIVES GREATER NUMBER OF SAMPLES PER DAY  SUITABLE FOR LAB WITH LESS STAFFS AS OUR ANALYZER IS AUTOMATED AND REQUIRES LESS MANPOWER.
  • 8. XE-5000 ANALYSIS PRINCIPLE  •Laser Flow Cytometry  •ShealthFlow/Hydrodynamic Focusing DC detection  •RF/DC Detection Method  •SLS Heamoglobin Method
  • 11. XE-5OO0 MULTICHANNEL ANALYZER CHANNEL PRINCIPLE PARAMETERS WBC/BASO Flow cytometry WBC,Baso #, Baso NRBC Flow cytometry NRBC #, NRBC % 4 Diff Flow cytomtery Lymph# , Lymph% Mono#, Mono% Eo# , Eo% Neut# , Neut% IG# , IG% RET/PLT-O Flow cytometry RET#, RET%,PLT-O, HFR, MFR, LFR, IRF RET-He, IPF IMI RF/DC-detection HPC# method HGB SLS-Method, HGB photometry MCH,MCHC,MCV RBC/PLT-Detector HDF DC-Detection RBC,HCT,PLT-I,RDW- method SD, RDW-CV, PDW, MPV, P-LCR
  • 14. WHY SYSMEX XE-5000??  Integrated Sysmex SP-Series automated slide maker/stainer.  eMM software provides more specific flagging.  Measure body fluids.  Advanced parameters
  • 15. WHY SYSMEX XE-5000 ? • HIGH THROUGHOUTPUT • NO NEED OF SAMPLE PREPARATION • SHORTENED TURN AROUND TIME • REDUCED SAMPLE VOLUME • LESS LIKEHOOD OF TRANSCRIPTIONAL ERRORS • PROVIDES 7 SCATTERGRAMS AND 2 HISTOGRAM FOR A BETTER ANALYSIS  RANKED BY THIRD PARTY AS HIGHEST VENDOR FOR RELIABILITY FOR 8 CONSECUTIVE YEARS IN A ROW*
  • 16. CUSTOMER SERVICE • In-time deliveries of reagents and consumable • Instrument repair and maintenance including hot-line support • Consultancy and management of complex laboratory installation projects • Continuous post-market surveillance and feedback of market requirements as design input for new product development • Management of customer events