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Radionuclide production methods ,[object Object],[object Object],[object Object]
Nuclear Reactor Pawitra Masa-at 4937092  SIRS/M February 14, 2007
Types of Reactors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Isotope Production Reactor ,[object Object],[object Object],[object Object]
Isotope Production Reactor Heat produced in reactor core is removed by cooling fluids and carried to steam generator (in power reactor) Cd or B, which absorb neutrons. They help to regulate the flux of neutrons. Inserted   to slow down the neutrons to make them more easily captured. Samples are stable isotope for radionuclide production from neutron capture reaction. U-235 also can be the target of (n,f) reaction for radionuclide production. *water or D2O can be coolant and moderator   at the same time.
Nuclear fission ,[object Object],[object Object],[object Object],[object Object]
Neutron interact with target in reactor n n n n n n n n n n n n Fast neutron Thermal neutron sample
Fission of U-236
Fission of U-236
Fission product of U-236 Example
Research reactor for radionuclide production
Fission reaction in fuel core 90 Br 143 Xe
Nuclear Fission Reactor production of  99 Mo ,[object Object],[object Object]
Production via Neutron Activation ,[object Object],[object Object],[object Object]
Type of reaction from Neutron activation methods ,[object Object],[object Object],For  En~ 100 keV Fast neutron For  En~ 0.025 eV Thermal neutron.
For  production,  which is most common, the element does not change,  so it is difficult  to get carrier-free product. Ex Ex Thermal neutron capture
Fast neutron capture Ex For (n,p) reaction  the number of proton (Z) change,  the so the radionuclide is  carrier-free product.
Some radionuclide used in Nuclear medicine
Calculate Activity of Radionuclide Production t = infinity    saturation factor = 1  So  …………………………………………………………………………………………………… . activity Half-life
What’s happening in the surface target ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Microscopic cross-section ,[object Object],[object Object]
Macroscopic cross-section ,[object Object],[object Object],[object Object],[object Object],Note Macroscopic cross-section have unit of inverse length (nuclei/cm 3 )*(cm 2 /nucles)=cm -1
Target cross-section
Concept of neutron flux ,[object Object],[object Object]
Neutron Flux density in Reactor graphite *For Neutron source (isotope type) Fuel rod control rod sample
Calculate Activity of Radionuclide Production For a mass (w) of the element  The total number of target nuclei , for isotopic abundance.
Reactor Radioisotopes used in medicine   ,[object Object],[object Object],[object Object],[object Object]
Reactor Radioisotopes used in medicine ,[object Object],[object Object],[object Object],[object Object],[object Object]
Reactor Radioisotopes used in medicine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Reactor Radioisotopes used in medicine ,[object Object],[object Object],[object Object],[object Object],[object Object]
Reactor Radioisotopes used in medicine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion -Product atom has same charge -Low specific activity -Short half-life -expensive Disadvantage -Less expensive -Product atom has different charge -High specific activity Advantage -Target bombarded   with neutron. -Target bombarded with charged particles (proton, deuteron). Definition of  the method Nuclear reactor Accelerators
Thank You    นางสาวปวิตรา  หมะสะอะ  4937092 SIRS/M

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Radionuclide production methods using nuclear reactors and accelerators

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  • 2. Nuclear Reactor Pawitra Masa-at 4937092 SIRS/M February 14, 2007
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  • 6. Isotope Production Reactor Heat produced in reactor core is removed by cooling fluids and carried to steam generator (in power reactor) Cd or B, which absorb neutrons. They help to regulate the flux of neutrons. Inserted to slow down the neutrons to make them more easily captured. Samples are stable isotope for radionuclide production from neutron capture reaction. U-235 also can be the target of (n,f) reaction for radionuclide production. *water or D2O can be coolant and moderator at the same time.
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  • 8. Neutron interact with target in reactor n n n n n n n n n n n n Fast neutron Thermal neutron sample
  • 11. Fission product of U-236 Example
  • 12. Research reactor for radionuclide production
  • 13. Fission reaction in fuel core 90 Br 143 Xe
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  • 17. For production, which is most common, the element does not change, so it is difficult to get carrier-free product. Ex Ex Thermal neutron capture
  • 18. Fast neutron capture Ex For (n,p) reaction the number of proton (Z) change, the so the radionuclide is carrier-free product.
  • 19. Some radionuclide used in Nuclear medicine
  • 20. Calculate Activity of Radionuclide Production t = infinity  saturation factor = 1 So …………………………………………………………………………………………………… . activity Half-life
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  • 26. Neutron Flux density in Reactor graphite *For Neutron source (isotope type) Fuel rod control rod sample
  • 27. Calculate Activity of Radionuclide Production For a mass (w) of the element The total number of target nuclei , for isotopic abundance.
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  • 33. Conclusion -Product atom has same charge -Low specific activity -Short half-life -expensive Disadvantage -Less expensive -Product atom has different charge -High specific activity Advantage -Target bombarded with neutron. -Target bombarded with charged particles (proton, deuteron). Definition of the method Nuclear reactor Accelerators
  • 34. Thank You  นางสาวปวิตรา หมะสะอะ 4937092 SIRS/M