Jackie will create title slide. We will keep current colors.
JW
JW: this is raw crystallography data, collected at OHSU. This is visual, high resolution, data
JW: this is raw crystallography data, collected at OHSU. This is visual, high resolution, data
The image then gets integrated along the spots, transforming the image into a series of mathematical values
The image then gets integrated along the spots, transforming the image into a series of mathematical values
The image then gets integrated along the spots, transforming the image into a series of mathematical values
The image then gets integrated along the spots, transforming the image into a series of mathematical values
Need to define reproducibility and reuseReproducibility is problem of validating scienceReuse is a problem of efficiencyNeed data reuse story- misquote or recollection of data because data wasn’t available
The image then gets integrated along the spots, transforming the image into a series of mathematical values
The “model’ we are used to seeing is actually a mathematical representation of how well a model (the sticks) fits into the mathematical distillation of the raw image. This looks static, but is actually a best representaiton along one axis of the data (which is to say, confidence levels). Crystallography boils down to solving the “phase problem”, which can be done two ways: brute force (holy hell!), and by using an exisitng model as a jumping off point. This is the fastest and most efficient way of solving off structures, and is, in fact, what I did to solve this structure. I got the previously published data from pdb.org, which is also where I deposited my data.The point of this is three fold: 1) data comes in many shapes and forms, 2) data transforms, and 3) data helps inform more data.
Standard yet Flexible data format, while encouraging the use and further development of community standards.Data are linked both to and from the corresponding publication and, where appropriate, to and from select specialized data repositories (e.g. GenBank).Assigns data Digital Object Identifiers (DOIs) to data so that researchers can gain professional credit through data citation.Promotes data visibility by allowing content to be indexed, searched and retrieved through interfaces designed for both humans and computers.Contents are free to download and have no legal barriers to reuse.Contents are curated to ensure the validity of the files and metadata.Submitters may updatedatafiles when corrections or additions are desired, without overwriting the original version linked from the article.Long-term preservation ... b