The mansa dhatu is formed from its predecessor rakta dhatu (रक्त धातुः). When Rakta dhatu is subjected to the process of micro-transformation (सूक्ष्मपचनम्), one processed part of it is specifically utilized to provide nourishment to the next dhatu in order i.e. Mansa Dhatu (मांस धातुः). This part is responsible for development and nourishment of mansa dhatu in body. Transformation of this fluid part of rakta into solid form mansa happens due to action of vayu (वायुः), jalam (जलम्) and tejas (तेजः) mahabhutas.[