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BQAERLA: a formula for  (most)  hypothesis-driven research ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Background ,[object Object],[object Object]
Question(s) ,[object Object],[object Object],[object Object]
Approach ,[object Object],[object Object]
Experiment and Results ,[object Object],[object Object]
What’s the difference between Literal and Author Interpretations? ,[object Object],[object Object]
Biol-311L Cell Biology Techniques Oral Presentation Instructions Prepare a 10-12 minute presentation using  PowerPoint .  You will present your PowerPoint to a group of colleagues at one of the presentation sessions (date and time TBA, see BlackBoard).  This presentation is physically due by email or on some sort of disk (floppy, CD or ZIP) three hours before the start of the session.  The order of presentations will be determined at the beginning of the session, so be prepared to go first.  If you made the presentation on a home/personal computer, then you should try it on a college computer prior to submitting it. Consider the following: What  Background  information needs to be understood? What cellular processes and what are the Big Questions about the cellular process? What gene/protein are you talking about? What is known about this protein? Does it have any interesting domains? What are their molecular/biochemical functions? Does it have relatives (paralogues or orthologues) and what do they do? How are the biochemical functions and cellular role required by the tissue and whole organism? What is not known? Questions ? The focus of the presentation is one to three figures worth of  primary data .  The data that you present may be your own RNAi experiment  or  published data about your  C. elegans  gene  or  a homologue.  Data that provides insight into some significant aspect of the biology of the gene/protein is required .  What are the  Approaches  being employed to answer the  Questions ? Is there an hypothesis (what is the proposed answer to the questions)? What is the  Experiment  being presented?  How did you (or someone else) generate the  Result ? What is the  Result (s)? What is the  Literal  interpretation of the  Result ? What can be concluded? What is/are the  Author's   or your  interpretations of the  Result ? What might be done next?
 
Approach Question Experiment Result Literal Interp. Author Interp. 2004 Cohort
Approach Question Experiment Result Literal Interp. Author Interp. 2005 Cohort
Approach Question Experiment Result Literal Interp. Author Interp. Peer Evaluation  (2004 cohort)
The “Formula” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The “Formula” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Sections of a research paper Abstract Introduction Materials and  Methods Results Discussion
The “Formula” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Sections of a research paper Abstract Introduction Materials and  Methods Results Discussion
The “Formula” ,[object Object],[object Object],[object Object],[object Object],[object Object],Sections of a research proposal Background Specific Aims The reasons a proposed experiment is important, necessary, logical, interesting, etc.
The “Formula” ,[object Object],[object Object],[object Object],[object Object],[object Object],Sections of a research proposal Background Specific Aims The reasons a proposed experiment is important, necessary, logical, interesting, etc.

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Biowriting

  • 1.
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. Biol-311L Cell Biology Techniques Oral Presentation Instructions Prepare a 10-12 minute presentation using PowerPoint . You will present your PowerPoint to a group of colleagues at one of the presentation sessions (date and time TBA, see BlackBoard). This presentation is physically due by email or on some sort of disk (floppy, CD or ZIP) three hours before the start of the session. The order of presentations will be determined at the beginning of the session, so be prepared to go first. If you made the presentation on a home/personal computer, then you should try it on a college computer prior to submitting it. Consider the following: What Background information needs to be understood? What cellular processes and what are the Big Questions about the cellular process? What gene/protein are you talking about? What is known about this protein? Does it have any interesting domains? What are their molecular/biochemical functions? Does it have relatives (paralogues or orthologues) and what do they do? How are the biochemical functions and cellular role required by the tissue and whole organism? What is not known? Questions ? The focus of the presentation is one to three figures worth of primary data . The data that you present may be your own RNAi experiment or published data about your C. elegans gene or a homologue. Data that provides insight into some significant aspect of the biology of the gene/protein is required . What are the Approaches being employed to answer the Questions ? Is there an hypothesis (what is the proposed answer to the questions)? What is the Experiment being presented? How did you (or someone else) generate the Result ? What is the Result (s)? What is the Literal interpretation of the Result ? What can be concluded? What is/are the Author's or your interpretations of the Result ? What might be done next?
  • 8.  
  • 9. Approach Question Experiment Result Literal Interp. Author Interp. 2004 Cohort
  • 10. Approach Question Experiment Result Literal Interp. Author Interp. 2005 Cohort
  • 11. Approach Question Experiment Result Literal Interp. Author Interp. Peer Evaluation (2004 cohort)
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.