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ANTIDEPRESSANTS www.freelivedoctor.com
Classification of Major Affective Disorders www.freelivedoctor.com
Episodal (reactive) Depression ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Reactive (episodal) Depression ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Major  Endogenous Depression   ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Major  Endogenous Depression   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Major  Endogenous Depression   ,[object Object],[object Object],[object Object],www.freelivedoctor.com
Mania ,[object Object],www.freelivedoctor.com
Mania ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
III.  Biological Correlates of Depression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
IV. Biological Basis for Depression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
[object Object],[object Object],[object Object],V.  Biogenic Theory of Depression www.freelivedoctor.com
VI.  NE System ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
VII.  Serotonin System ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Antidepressants ,[object Object],MAOIs SSRIs TCAs TCAs TCAs TCAs SSRIs SSRIs SSRIs SSRIs MAOIs MAOIs MAOIs MAOIs MAOIs MAOIs Venflaxine Venflaxine Venflaxine MAOIs MAOIs maprotiline Amoxepine doxepin isocarboxazide Nortriptyline www.freelivedoctor.com
Antidepressants ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Mechanism of Action ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
Tricyclic Antidepressants (TCAs) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],www.freelivedoctor.com
X. MAO INHIBITORS ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XI. SSRIs ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XI. SSRIs ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XI. SSRIs ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XI. SSRIs ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XI. SSRIs ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XII. Heterocyclics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XII. Heterocyclics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XII. Heterocyclics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XII. Heterocyclics ,[object Object],[object Object],www.freelivedoctor.com
XII. Heterocyclics ,[object Object],[object Object],www.freelivedoctor.com
XII. Heterocyclics  Third Generation   ,[object Object],[object Object],[object Object],www.freelivedoctor.com
XII. Atypical/Heterocyclic  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Similar to TCAs 5-HT antagonists  2-AR antagonist SSRI-like  NE output www.freelivedoctor.com
Noradrenergic Control of Serotonergic Release NE 5-HT NE  2 -AR  1 -AR 1 2 3 Mianserin 5-HT1   5-HT2 5-HT3 Receptors www.freelivedoctor.com
XIV.  Alternative Therapies ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
www.freelivedoctor.com
www.freelivedoctor.com
www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs PIP PIP 2 G IP 3 IP 2 IP 1 Inositol PI X Li + PLC DAG Ca  2+ www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com
XVI. Anti-Manic Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],www.freelivedoctor.com

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Anti depressants

Editor's Notes

  1. High correlation particularly among kin Reserpine, a drug used in the treatment o hypertension and schizophrenia can cause depression because it depletes the vesicular storage of amine neurotransmitters (NE, 5-HT, DA). Depression could be relieved by isoniazid, a drug used in the treatment of tuberculosis. TCAs, MAOIs, SSRIs, and all the new drugs. ECT causes a massive release of NTs and is a very effective antidepressant.