You have learned for years how to do big enterprise applications with big enterprise frameworks. Sometimes it was good, but sometimes it was over-engineered, rarely fun. It changed a lot a few years ago with Asp.Net Mvc and with a lot of impulse of the community. But today, the web moves faster and faster, and people want tools that do the job in a simple way and that just works. Today we have these tools in .Net and they grow every day for our pleasure.
Get an overview of why you should care about Simplicity and how you can build great web apps in a simpler way with small frameworks and tools "that just work" (with pieces of NancyFx, SimpleData, RavenDb, Nuget, jQuery, Markdown, Bootstrapper, ...)
Slides of my #Web.Net conference 2012 in Milano