Monckeberg's arteriosclerosis, also known as medial calcific sclerosis, is a type of dystrophic calcification that occurs in the tunica media of medium-sized arteries in individuals over 50 years of age. It is characterized by the physiological thickening and loss of elasticity of arterial walls due to calcific deposits in the media, which can be seen on x-rays and palpated in peripheral vessels, but typically does not cause lumen narrowing or clinical significance. Microscopically, calcification appears as concentric blue rings or basophilic granules in the media, while the intima and adventitia remain intact.

1. Monckeberg’s
Arteriosclerosis

2. It is also known as medial calcific
sclerosis.
Arteriosclerosis is thickening and loss of
elasticity of arterial walls.
In it Calcific deposits which is a type of
dystrophic calcification in the tunica
media of medium sized arteries seen.

3. It is a physiological phenomenon
usually seen in persons over 50 years
of age.it has little or no clinical
significance.
Mostly affected vessels are muscular
arteries of extremities and arteries
supplying femal genital tract.

4. Medial calcification is often an
incidental finding in x ray of affected
sites.
Grossly the involved blood vessels
undergoes calcification and thickening
which can be palpated for peripheral
vessels.
It produces pipestem like rigid tube
without causing narrowing of lumen.

5. Microscopically Monckeberg’s
arteriosclerosis is characterized by
deposits of calcium salts in the media in
the form of concentric blue rings or
basophilic coarse granules without
associated inflammatory reaction.
Intima and adventitia remain intact.

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