Solid Lipid Nanoparticles (SLN) is recently developed technique, in which the size ranges from 1 to 1000 nm particles can use for drug delivery
system (DDS). It is basically a colloidal carrier. In this review based on the latest research and development of SLN according to the modern literature are cited. The ability to incorporate drugs into Nanoparticulate system offers a new prototype in drug delivery that could use for drug
targeting. The preparation techniques for production of SLN are Novel and more efficient. Appropriate analytical techniques for the
characterization of SLN. Solid lipid nanoparticles (SLN) have emerged as a next-generation drug delivery system with potential applications in pharmaceutical field, cosmetics, research, clinical medicine and other allied sciences. Recently, increasing attention has been focused on theseSLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs.