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The body’s defenders
Core concepts ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Keywords ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathogens and disease Bacteria Fungi Viruses Protozoa Large parasites
Two major types of defenses INNATE (NONSPECIFIC) IMMUNITY  Rapid responses to a  broad range of microbes ACQUIRED (SPECIFIC) IMMUNITY Slower responses to  specific microbes External defenses Internal defenses Skin Mucous membranes Secretions Phagocytic cells Antimicrobial proteins Inflammatory response Natural killer cells Humoral response (antibodies) Cell-mediated response (cytotoxic  lymphocytes) Invading microbes (pathogens)
Innate (nonspecific) immunity  First line: External defenses External defenses
Innate immunity  Second line: Internal defenses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],1 2 3 4 5 6 Microbes MACROPHAGE Vacuole Lysosome containing enzymes Phagocytic cell
[object Object],Innate immunity  Second line: Internal defenses (con’t.) http://www.sumanasinc.com/webcontent/anisamples/dynamicillustrations/inflammatory.html ,[object Object],[object Object],[object Object],[object Object],[object Object]
Innate immunity  Second line: Internal defenses (con’t.) ,[object Object],[object Object],[object Object],[object Object]
Specific (acquired) immunity Third line of defense ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object]
MHC molecules and T cell function ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Antibody action
Immunity   – memory cells initiate a faster, more efficient response upon reinfection
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Blood groups and transfusions ,[object Object],[object Object],[object Object]
Immune disorders/diseases ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],1µm

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Presentation 11 - Immunity

  • 2.
  • 3.
  • 4. Pathogens and disease Bacteria Fungi Viruses Protozoa Large parasites
  • 5. Two major types of defenses INNATE (NONSPECIFIC) IMMUNITY Rapid responses to a broad range of microbes ACQUIRED (SPECIFIC) IMMUNITY Slower responses to specific microbes External defenses Internal defenses Skin Mucous membranes Secretions Phagocytic cells Antimicrobial proteins Inflammatory response Natural killer cells Humoral response (antibodies) Cell-mediated response (cytotoxic lymphocytes) Invading microbes (pathogens)
  • 6. Innate (nonspecific) immunity First line: External defenses External defenses
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.  
  • 12.
  • 13.
  • 15. Immunity – memory cells initiate a faster, more efficient response upon reinfection
  • 16.
  • 17.
  • 18.