3. Objectives
On completion of this presentation, you
should be able to
• diagnose various types of hypospadias upon
clinical examination
• elaborate features to look for in hypospadiac
genitalia
• decide when to evaluate for a DSD
18. Disorder of sexual differentiation
Rule of 2/3
If any of two of three genital structures are
abnormal then evaluate for DSD
e.g. Hypospadias with unilateral UDT
• Kaefer M, Diamond D, Hendren WH, et al. The incidence of intersexuality in children with
cryptorchidism and hypospadias: stratification based on gonadal palpability and meatal
position. J Urol 1999;162:1003 –6