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NUR ANISAH BAGIAN HISTOLOGI & BIOLOGI SEL, FAKULTASKEDOKTERAN,  UNIVERSITAS GADJAH MADA, YOGYAKARTA Blok Sistem Reproduksi, 9 Feb 2010 [04] SISTEM REPRODUKSI WANITA
Sistem reproduksi wanita memiliki enam fungsi utama: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
GAMBARAN UMUM  SISTEM REPRODUKSI WANITA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ORGANA GENITALIA FEMININA ,[object Object],[object Object]
Organa genitalia feminina interna dan externa Ø lateral organa genitalia feminina
Figure . Internal organs of the female reproductive system.
1.  Ovarium ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Figure 23—2. Ovary of a woman of reproductive age showing its main components: germinal epithelium, tunica albuginea, cortical region, and medullary region.
Figure. Photomicrograph of part of  an ovary showing the cortical and medullary regions. H&E stain. Low magnification. Ovary human, H&E
Folliculus ovarii ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fig. Types of ovarian follicles, from primordial to mature. The relative proportions of the follicles are not maintained in this drawing.
Perkembangan folikel ,[object Object],[object Object],[object Object]
Figure 23—6. Cortical region of an ovary. Besides primordial follicles formed by an oocyte and flat follicular cells, a few follicles at the initial stage of growth (unilaminar primary follicles) are present. These are formed by an oocyte and one layer of cuboidal granulosa cells. Pararosaniline—toluidine blue (PT) stain. Low magnification.
Figure 23—7. Photomicrograph of a preantral ovarian follicle formed by an oocyte and several layers of granulosa cells. The oocyte is surrounded by the zona pellucida. Picrosirius-hematoxylin (PSH) stain. Medium magnification.
Folliculus secundarius Folliculus de Graaf
Figure 23—9. Photomicrograph of part of an antral follicle. Cavities (A) that appear in the granulosa layer will fuse and form one large cavity, the antrum. The oocyte is surrounded by the zona pellucida. Granulosa cells (G) surround the oocyte and cover the wall of the follicle. A theca can be seen around the follicle. H&E. Medium magnification.
Figure 23—10. Photomicrograph of an antral follicle showing the oocyte surrounded by the granulosa cells of the corona radiata and supported by the cells of the cumulus oophorus. The remaining granulosa cells form the wall of the follicle and surround the large antrum. A theca surrounds the whole follicle. PT stain. Medium magnification.
Figure 23—11. Photomicrograph of a small part of the wall of an antral follicle, showing the antrum, the layer of granulosa cells, and the thecas. The theca interna surrounds the follicle, and its cells appear lightly stained because their cytoplasm contains lipid droplets, a characteristic of steroid-producing cells. The theca interna is surrounded by the theca externa, which merges with the stroma of the ovary. A basement membrane separates the granulosa layer from the theca interna. PT stain. High magnification.
Figure 23—12. Photomicrograph of the atresia of a follicle characterized by: (1) the death of granulosa cells, many of which are seen loose in the antrum; (2) loss of the cells of the corona radiata; and (3) the oocyte floating free within the antrum. PT stain. Medium magnification.
Figure 23—13. Part of a corpus luteum. Granulosa lutein cells, which constitute the majority of the cells, derive from the granulosa layer.  They are larger and stain more lightly than the theca lutein cells, which originate from the theca interna.
Figure 23—14. Photomicrograph of a small portion of a corpus luteum. Most cells present in the figure are granulosa lutein cells. PT stain. High magnification.
Figure 23—15. Pituitary hormones control most ovarian functions. Follicle-stimulating hormone (FSH) stimulates follicular growth and synthesis of estrogen by the granulosa cells. -  Luteinizing hormone (LH) induces ovulation and transforms the granulosa layer and the theca interna into an actively secreting gland, the corpus luteum.  - Estrogen and progesterone produced in the ovary act on the hypothalamus, stimulating or inhibiting the liberation of gonadotropin-releasing hormone (GnRH).
Figure 23—16. Corpus albicans, the scar of connective tissue that replaces a corpus luteum after its involution.
Corpus luteum
Corpus albicans ,[object Object],[object Object]
2.  Tuba uterina (oviduct) ,[object Object],[object Object],[object Object],[object Object]
Bagian-bagian tuba uterina ,[object Object],[object Object],[object Object],[object Object]
Figure 23—17. Photomicrograph of part of the wall of an oviduct. The highly folded mucosa indicates that this region is close to the ovary. PT stain. Low magnification.
Figure 23—18. Photomicrograph of the epithelial lining of an oviduct. The epithelial lining is formed by ciliated and more darkly staining nonciliated secretory cells. Ciliated cells contribute to the movement of the oocyte or conceptus to the uterus. PT stain. High magnification.
Struktur dinding tuba uterina ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tuba uterina (tuba Fallopii)
Ampula & ismus tuba uterina
3.  Uterus ,[object Object],[object Object]
Bagian-bagian uterus: ,[object Object],[object Object],[object Object]
Struktur dinding uterus: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Uterus ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Tipe leiomyoma kecil
Endoserviks
Serviks uteri
Carsinoma cervix ,[object Object],[object Object],[object Object],[object Object]
Korpus uteri fase haid
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vagina
Vagina
5.  Apparatus genitalia externa ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Siklus menstruasi ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Endometrium proliferatif
Endometrium proliferatif
Endometrium
Endometrium
Endometrium: permulaan menstruasi
Permukaan endometrium
Endometrium: pasca menopause
Endometrium pasca menopause
Miometrium
Fertilisasi dan implantasi
Plasenta
 
 
Desidua ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Desidua
Plasenta tahap awal
Bagian tepi vilus
Plasenta muda
Plasenta tua
Plasenta tua
Membran janin
Funikulus umbilikalis
Funikulus umbilikalis (tali pusat)
GLANDULA MAMMAE
-  Schematic drawing of the female breast showing inactive and active mammary glands.  - Each lactiferous duct with its accompanying smaller ducts is a gland in itself and constitutes the lobes of the gland.
Figure 23—28. Changes in the mammary gland. A: In nonpregnant women, the gland is quiescent and undifferentiated, and its duct system is inactive. B: During pregnancy, alveoli proliferate at the ends of the ducts and prepare for the secretion of milk. C: During lactation, alveoli are fully differentiated, and milk secretion is abundant. Once lactation is completed, the gland reverts to the nonpregnant condition.
Glandula mammae
STRUKTUR MAMMAE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Photomicrograph of lactating mammary gland. Several alveoli are filled with milk, visible as granular material.  The vacuoles in the lumen and in the alveolar cell cytoplasm represent the lipid portion of milk.  PT stain. Medium magnificatio n.
Figure 23—30. Secreting cells from the mammary gland. From left to right, note the accumulation and extrusion of lipids and proteins.  The proteins are released through exocytosis.
Glandula mammae
Kelenjar mamma non-aktif
Glandula mammae selama kehamilan
Glandula mammae dalam masa laktasi
Kelenjar mamma dalam masa laktasi
ORGANA GENITALIA FEMININA ,[object Object],[object Object]
ORGANA GENITALIA EXTERNA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
FUNGSI : ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Klitoris
Labium minus
Labium mayus

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systema-genitalia-feminina

  • 1. NUR ANISAH BAGIAN HISTOLOGI & BIOLOGI SEL, FAKULTASKEDOKTERAN, UNIVERSITAS GADJAH MADA, YOGYAKARTA Blok Sistem Reproduksi, 9 Feb 2010 [04] SISTEM REPRODUKSI WANITA
  • 2.
  • 3.
  • 4.
  • 5. Organa genitalia feminina interna dan externa Ø lateral organa genitalia feminina
  • 6. Figure . Internal organs of the female reproductive system.
  • 7.
  • 8. Figure 23—2. Ovary of a woman of reproductive age showing its main components: germinal epithelium, tunica albuginea, cortical region, and medullary region.
  • 9. Figure. Photomicrograph of part of an ovary showing the cortical and medullary regions. H&E stain. Low magnification. Ovary human, H&E
  • 10.
  • 11. Fig. Types of ovarian follicles, from primordial to mature. The relative proportions of the follicles are not maintained in this drawing.
  • 12.
  • 13. Figure 23—6. Cortical region of an ovary. Besides primordial follicles formed by an oocyte and flat follicular cells, a few follicles at the initial stage of growth (unilaminar primary follicles) are present. These are formed by an oocyte and one layer of cuboidal granulosa cells. Pararosaniline—toluidine blue (PT) stain. Low magnification.
  • 14. Figure 23—7. Photomicrograph of a preantral ovarian follicle formed by an oocyte and several layers of granulosa cells. The oocyte is surrounded by the zona pellucida. Picrosirius-hematoxylin (PSH) stain. Medium magnification.
  • 16. Figure 23—9. Photomicrograph of part of an antral follicle. Cavities (A) that appear in the granulosa layer will fuse and form one large cavity, the antrum. The oocyte is surrounded by the zona pellucida. Granulosa cells (G) surround the oocyte and cover the wall of the follicle. A theca can be seen around the follicle. H&E. Medium magnification.
  • 17. Figure 23—10. Photomicrograph of an antral follicle showing the oocyte surrounded by the granulosa cells of the corona radiata and supported by the cells of the cumulus oophorus. The remaining granulosa cells form the wall of the follicle and surround the large antrum. A theca surrounds the whole follicle. PT stain. Medium magnification.
  • 18. Figure 23—11. Photomicrograph of a small part of the wall of an antral follicle, showing the antrum, the layer of granulosa cells, and the thecas. The theca interna surrounds the follicle, and its cells appear lightly stained because their cytoplasm contains lipid droplets, a characteristic of steroid-producing cells. The theca interna is surrounded by the theca externa, which merges with the stroma of the ovary. A basement membrane separates the granulosa layer from the theca interna. PT stain. High magnification.
  • 19. Figure 23—12. Photomicrograph of the atresia of a follicle characterized by: (1) the death of granulosa cells, many of which are seen loose in the antrum; (2) loss of the cells of the corona radiata; and (3) the oocyte floating free within the antrum. PT stain. Medium magnification.
  • 20. Figure 23—13. Part of a corpus luteum. Granulosa lutein cells, which constitute the majority of the cells, derive from the granulosa layer. They are larger and stain more lightly than the theca lutein cells, which originate from the theca interna.
  • 21. Figure 23—14. Photomicrograph of a small portion of a corpus luteum. Most cells present in the figure are granulosa lutein cells. PT stain. High magnification.
  • 22. Figure 23—15. Pituitary hormones control most ovarian functions. Follicle-stimulating hormone (FSH) stimulates follicular growth and synthesis of estrogen by the granulosa cells. - Luteinizing hormone (LH) induces ovulation and transforms the granulosa layer and the theca interna into an actively secreting gland, the corpus luteum. - Estrogen and progesterone produced in the ovary act on the hypothalamus, stimulating or inhibiting the liberation of gonadotropin-releasing hormone (GnRH).
  • 23. Figure 23—16. Corpus albicans, the scar of connective tissue that replaces a corpus luteum after its involution.
  • 25.
  • 26.
  • 27.
  • 28. Figure 23—17. Photomicrograph of part of the wall of an oviduct. The highly folded mucosa indicates that this region is close to the ovary. PT stain. Low magnification.
  • 29. Figure 23—18. Photomicrograph of the epithelial lining of an oviduct. The epithelial lining is formed by ciliated and more darkly staining nonciliated secretory cells. Ciliated cells contribute to the movement of the oocyte or conceptus to the uterus. PT stain. High magnification.
  • 30.
  • 31. Tuba uterina (tuba Fallopii)
  • 32. Ampula & ismus tuba uterina
  • 33.
  • 34.
  • 35.
  • 36.
  • 40.
  • 42.
  • 45.
  • 46.  
  • 47.
  • 48.  
  • 49.  
  • 61.  
  • 62.  
  • 63.
  • 74. - Schematic drawing of the female breast showing inactive and active mammary glands. - Each lactiferous duct with its accompanying smaller ducts is a gland in itself and constitutes the lobes of the gland.
  • 75. Figure 23—28. Changes in the mammary gland. A: In nonpregnant women, the gland is quiescent and undifferentiated, and its duct system is inactive. B: During pregnancy, alveoli proliferate at the ends of the ducts and prepare for the secretion of milk. C: During lactation, alveoli are fully differentiated, and milk secretion is abundant. Once lactation is completed, the gland reverts to the nonpregnant condition.
  • 77.
  • 78. Photomicrograph of lactating mammary gland. Several alveoli are filled with milk, visible as granular material. The vacuoles in the lumen and in the alveolar cell cytoplasm represent the lipid portion of milk. PT stain. Medium magnificatio n.
  • 79. Figure 23—30. Secreting cells from the mammary gland. From left to right, note the accumulation and extrusion of lipids and proteins. The proteins are released through exocytosis.
  • 83. Glandula mammae dalam masa laktasi
  • 84. Kelenjar mamma dalam masa laktasi
  • 85.
  • 86.
  • 87.
  • 88.