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What's Your Gut Feeling? Using microbiome as Your Secret Tool - Dr. Tiffany Vora
- 1. The Microbiome: What’s Your Gut Feeling? Dr. Tiffany Vora April 23, 2019
- 3. Shutterstock
- 4. David et al., Genome Biology 2014 Kang et al., Cell Reports 2018
- 5. Images courtesy of Shutterstock and CDC/James Gathany Bactana Ascus Biosciences Trace Genomics Indigo Agriculture BioAg Alliance Boost Biomes QuantuMDx Sandia Cue
- 10. Bacteroides fragilis Sgritta et al., Neuron 2018 Commercially available probiotic!
- 11. Shutterstock Drag And Drop Biological Engineering
- 13. Based on van Nood et al., NJEM 368;5 (2013)
- 14. ● Infections ○ Gut ○ Nose/lungs ○ Skin ● Food sensitivity ● Birth/c-sections ● Behavior
- 15. Shutterstock
- 16. I would invest today in a company that’s ❏ Developing new probiotics ❏ Building and selling smart toilets ❏ Commercializing Fecal Microbiome Transplants ❏ Developing drugs that target the microbiome
- 18. CDC Global Panigrahi et al., Nature 2017 ● 4,556 infants ● L. plantarum ● Daily dose, 1 week CAD $1.3 ● Sepsis ↓40% ● Infection ↓75-80% ● Pneumonia ↓34% ● No side effects
- 19. Ridaura et al., Science 2013 CDC/Dr. Lyle Conrad Smith et al., Science 2013Shutterstock
- 20. Shutterstock
- 21. 2016 2 in 5 adults are overweight or obese 2 in 12 adults have type 2 diabetes Data from the 2016 Global Nutrition Report Shutterstock
- 22. 667 million children <5 years old 155 million children are stunted 52 million children are wasted Data from the 2016 Global Nutrition Report Shutterstock 41 million children are overweight
- 23. ShutterstockBlack et al., The Lancet, 2008
- 24. 2016 Global Nutrition Report: Stunting, Wasting Overweight Adult obesity/overweight 2.1%, 0.5% 6.0% 67.3% 321 million people 38.7%, 15.1% 1.9% 22.0% 1.25 billion people 9.4%, 2.3% 6.6% 34.4% 1.4 billion people
- 25. Take it home ● Treat your body as an ecosystem The Good Gut I Contain Multitudes uBiome ● Play with the tech ● Stay tuned!
- 26. Thank you! Dr. Tiffany Vora Faculty Director Vice Chair, Digital Biology & Medicine tiffany.vora@su.org Remind me that we met at the SUCanada Summit!