6. Evolution: Early Systems. DX plain โ CDSS โ Diagnosis aid 1989 HELP โ HIS integrated with CDSS 1980 Current Systems MYCIN โ Infection management -Rule based, IF and THEN rules. PUFF โ LIS for interpretation of Pulmonary function test. 1976 INTERNIST 1 โ diagnosis 1974 AAPHELP โLeeds Abdominal Pain System 1972