Esophagus .pdf

MODERATOR:Dr.C.P.Das
PRESENTER:D.Ravindra
 Esophagus is a soft muscular tube that allows food to pass
from pharynx to the stomach
 It is Collapsed at rest,
 Flat in upper 2/3 & rounded in lower 1/3
 It is 25 cm in length
 Commences from the lower border of the cricoid
cartilage.(C6).
 Then it descends along the front of the spine, through the
posterior mediastinum, passes through the
Diaphragm, and, enters into the abdomen, terminates at the
cardiac orifice of the stomach, opposite to T11 vertebra.
In the newborn:
 Upper limit is at the level of-C4/C5 and
 Lower at T9
Length:
At birth: 8-10 cm,
End of 1st yr: 12cm,
5th Yr.:16cm
15th yr: 19cm
Diameter: Varies whether bolus of food/ fluid
passing through or not.
At rest in adults 20 mm but can stretch up to 30
mm
At birth it is 5mm, and at 5 yrs. it is 15mm
Primitive foregut forms
at 4th week of
gestation by a
longitudinal folding and
incorporation of the
dorsal part of the yolk
sac into the embryo
Then appears a small
diverticulum on the
ventral wall of the
foregut at the junction
with the pharyngeal gut
– „respiratory or
tracheobronchial
diverticulum‟
 This tracheobronchial
diverticulum separates
from the developing
oesophagus by the
formation of the
oesophagotracheal septum
 The developing
oesophagus is a short tube
which extends from the
tracheobronchial
diverticulum to the future
stomach
 As oesophagus lengthens
the heart and lungs
descend caudally
Upper two thirds is striated and innervated by
vagus and lower third is smooth muscle and
innervated by splanchnic plexus.
Circular muscle coat is formed by the surrounding
mesenchyme at 6th week
Longitudinal muscle coat forms at 10-15th week
At 7th week lumen is filled with cells but few
vacuoles are present.
At 10th week lumen is completely restored
Blood vessels enter the esophageal wall at 7th month
OESOPHAGEAL ATRESIA/TRACHEO-
OESOPHAGEAL FISTULA.:
Due to:
Spontaneous posterior deviation of oesophago
tracheal septum.
Mechanical factor pushing dorsal wall of
foregut anteriorly.
Esophagus .pdf
Esophagus .pdf
Esophagus .pdf
Anterior Curvature:
 It Follows antero-
posterior curve of
vertebral column
through neck, thorax
(posterior mediastinum)
& upper abdomen
Midline infront of
prevertebral fasia
Then inclines
slightly to left.
(enters thoracic
inlet)
again at T5
midline
at T7 again
deviates to left
Passes infront of
thoracic aorta.
Site Vertebral
Level
Distance from
central incisor
Cricopharynx C 6 15 cm
Aortic arch T 4 25 cm
Lt main
bronchus
T 5 28 cm
Oesophageal
hiatus
T 10 40 cm
 The most common site of oesophageal
impaction is at the thoracic inlet
 The cricopharyngeus sling at C6 is also at
this level and may "catch" a foreign body.
 About 70% of blunt foreign bodies that
lodge in the oesophagus do so at this
location.
 Another 15% become lodged at the mid
oesophagus, in the region where the aortic
arch and carina overlap the oesophagus on
chest radiograph.
 The remaining 15% become lodged at the
lower oesophageal sphincter (LES) at the
gastroesophageal junction.
Topographically, there
are three distinct
regions:
cervical, thoracic, and
abdominal.
1.CERVICAL
OESOPHAGUS:
extends from the
pharyngoesophageal
junction to the
suprasternal notch.
about 4 to 5 cm long.
2.THORACIC
OESOPHAGUS:
 Extends from the
suprasternal
notchdiaphragmatic
hiatus.
Passes posterior to the
trachea, the tracheal
bifurcation, and the
left main stem
bronchus.
The esophagus lies
posterior and to the
right of the aortic
arch at the T4
vertebral level.
the esophagus lies
anteriorly to the aorta
from the level of T8
until the
diaphragmatic hiatus
3.ABDOMINAL
OESOPHAGUS:
Extends from the
diaphragmatic
hiatusorifice of the
cardia of the stomach.
Forms a truncated
cone, about 1 cm long.
Two high-pressure zones
prevent the backflow of
food:
The upper and
The lower esophageal
sphincter.
 Between pharynx and the
cervical oesophagus.
 Located at C5-C6 level.
 The UES is a
musculocartilaginous
structure.
 This is formed by fibers of
cricopharyngeus, part of the
inferior constrictor, which
encircles the oesophageal
entrance
The cricopharyngeus
muscle is a striated
muscle.
produces maximum
tension in the A.P
direction and less tension
in lateral direction.
composed of a mixture of
fast- and slow-twitch
fibres.
This muscle forms the
main component of UES.
The lower esophageal sphincter is a high-pressure
zone located where the esophagus merges with the
stomach.
Mean pressure here is approx. 8mm Hg.
The LES is a functional
unit composed of an
intrinsic and an extrinsic
component.
INTRINSICoesophagel
muscle fibers and is under
neurohormonal influence
EXTRINSICdiaphragm
muscle.
The endoscopic localization of the LES is
different from the manometric localization.
The endoscopic localizationdetermined by
changes in the esophageal mucosal transition
from nonstratified squamous esophageal
epithelium to the gastric mucosa “Z-
line”or B ring.
Functional location of LES is 3 cm distal to
the Z-line.
Esophagus .pdf
Bulbous distension of distal
oesophagusvestibule.
It corresponds to manometrically defined
LES.
1.Attachment of cranial end of oesophagus
 Longitudinal muscle attaches to the lamina of
the cricoid cartilage by means of a tendon –
CRICOOESOPHAGEAL tendon
2.Attachment of tubular oesophagus
 Attached to trachea, pleura, and prevertebral
fascia by several fibrous strands
3.Attachments of distal end
 Two diaphragmatic crura
 Phrenooesophageal ligament
Phernooesophageal ligament:
 Created by blending of the subdiaphragmatic fascia and
the endothoracic fascia
 Also known as LIMER‟S FASCIA, or ALLISON‟S
MEMBRANE
 Two sheaths- upper inserts into oesophageal tunica
muscularis and submucosa: lower inserts into gastric
serosa, and mesentry
Esophagus .pdf
1.Cervical part
 Trachea anteriorly
 RLN, carotid sheath
with contents &
lower pole of thyroid
glands laterally
 Posteriorly
prevertebral fascia
 Thoracic duct lies
behind the left
border
2.Thoracic part
In superior mediastinum
 Oesophagus lies
between trachea and
vertebral column
 It enters posterior
mediastinum behind
aortic arch at T4
 Left recurrent laryngeal
nerve & thoracic duct
are related posteriorly
 Laterally:
 left: arch of
aorta, vagus nerve, left
subclavian artery, pleura
 Right: azygous
vein, pleura
Thoracic part in posterior mediastinum
 Anteriorly Tracheal bifurcation , pericardium right
pulmonary artery, tracheobronchial lymph nodes
 Posteriorly vertebral column, long cervical
muscles, right posterior intercostal
arteries, thoracic duct , azygous vein and two hemi
azygous veins & thoracic aorta inferiorly.
 On left is descending thoracic aorta, pleura
 On right, right pleura and azygous vein
 Vagal fibers lie in close relation left vagus
anteriorly and right vagus posteriorly
3.Abdominal oesophagus
 Lies slightly left of median
plane
 Related to the posterior
surface of the left lobe of
the liver
 Right border is continuous
with lesser curvature & left
ends in the cardiac notch
 Covered by peritoneum
anteriorly
 Posteriorly lie left crus of
diaphragm and left inferior
phrenic artery
Four coats from outside
inwards:
1. Fibrous coat (adventitia)
2. Muscular coat (muscularis
propria)
3. Submucous coat
4. Mucous coat
Layer of loose, supportive fibrous tissue
Conducts major vessels & nerves longitudinally
A serosa formed by visceral peritoneum replaces
adventitia of intra-abdominal segment of
oesophagus
External longitudinal muscle
Internal circular muscle
Parasympathetic ganglia forming Auerbach's
nerve plexus lies b/w them
Upper 1/3: striated muscle
Middle 1/3: striated & smooth
Lower 1/3: smooth muscle
Esophagus .pdf
Loose supporting areolar tissue contains:
Serous and mucous glands
Blood vessels
Lymphatic channels
Parasympathetic ganglia forming Meissner's
nerve plexus
1. Epithelium: non-keratinizing stratified sqamous
epithelium
2. Lamina propria: loose areolar tissue with
lymphoid aggregates
3. Muscularis mucosae: produces local
movement of mucosa & helps in
drainage of gland secretions
Pink, smooth, protective
oesophageal mucosa
leads to red, mamillated,
secretory gastric mucosa
across Z (zigzag) line at
38-40 cm from incisors.
Higher Z line seen in
Barret‟s esophagus.
 The rich arterial supply of the
esophagus is segmental .
 Branches of the inferior thyroid
arteryUES and cervical
esophagus.
 Paired aortic esophageal
arteries or terminal branches of
bronchial arteriesthoracic
esophagus.
 The left gastric artery and a
branch of the left phrenic
arteryLES and the most distal
segment of the esophagus.
 The venous supply is also
segmental.
 From the dense submucosal
plexus the venous blood
drains into the superior vena
cava.
 veins of proximal and distal
esophagus azygous
system.
 Veins of mid
oesophaguscollaterals of
left gastric vein.
 The lymphatics from the proximal
1/3rddrain into the deep cervical
LNs subsequently into the
thoracic duct.
 Middle 1/3rd  into superior and
posterior mediastinal nodes.
 Distal 1/3rd gastric and celiac
lymph nodes.
Surgical Importance:
 Submucosal lymphatics explain why
tumours may extend long distance
before obstructing lumen
 May also explain high recurrence
rates
 Bidirectional lymph flow may
explain retrograde tumour seeding
if flow is blocked
 Parasympathetic nerve
supply:
(SENSORY,MOTOR,SECR
ETOMOTOR)
 Upper ½rec.laryngeal
nerve.
 Lower ½oesophageal
plexus formed by the 2
vagus plexus.
 The sympathetic nerve
supply(VASOMOTOR)
 Upper ½by fibres from
mid cervical ganglion.
 Lower ½directly from
upper four thoracic
ganglia.
 The ganglia that lie
between the longitudinal
and the circular
layersmyenteric or
Auerbach's plexus.
 That lie in the submucosa
form the submucous or
Meissner's plexus.
 Auerbach's
plexusregulates
contraction of the outer
muscle layers.
 Meissner's
plexusregulates
secretion and the
peristaltic contractions
of the muscularis
mucosae.
Scott&brown 6th edition
Grey‟s anatomy
Journal presentation by:
 Dr.Prathyusha
Thank you
1 sur 48

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Esophagus .pdf

  • 2.  Esophagus is a soft muscular tube that allows food to pass from pharynx to the stomach  It is Collapsed at rest,  Flat in upper 2/3 & rounded in lower 1/3  It is 25 cm in length  Commences from the lower border of the cricoid cartilage.(C6).  Then it descends along the front of the spine, through the posterior mediastinum, passes through the Diaphragm, and, enters into the abdomen, terminates at the cardiac orifice of the stomach, opposite to T11 vertebra.
  • 3. In the newborn:  Upper limit is at the level of-C4/C5 and  Lower at T9 Length: At birth: 8-10 cm, End of 1st yr: 12cm, 5th Yr.:16cm 15th yr: 19cm Diameter: Varies whether bolus of food/ fluid passing through or not. At rest in adults 20 mm but can stretch up to 30 mm At birth it is 5mm, and at 5 yrs. it is 15mm
  • 4. Primitive foregut forms at 4th week of gestation by a longitudinal folding and incorporation of the dorsal part of the yolk sac into the embryo Then appears a small diverticulum on the ventral wall of the foregut at the junction with the pharyngeal gut – „respiratory or tracheobronchial diverticulum‟
  • 5.  This tracheobronchial diverticulum separates from the developing oesophagus by the formation of the oesophagotracheal septum  The developing oesophagus is a short tube which extends from the tracheobronchial diverticulum to the future stomach  As oesophagus lengthens the heart and lungs descend caudally
  • 6. Upper two thirds is striated and innervated by vagus and lower third is smooth muscle and innervated by splanchnic plexus. Circular muscle coat is formed by the surrounding mesenchyme at 6th week Longitudinal muscle coat forms at 10-15th week At 7th week lumen is filled with cells but few vacuoles are present. At 10th week lumen is completely restored Blood vessels enter the esophageal wall at 7th month
  • 7. OESOPHAGEAL ATRESIA/TRACHEO- OESOPHAGEAL FISTULA.: Due to: Spontaneous posterior deviation of oesophago tracheal septum. Mechanical factor pushing dorsal wall of foregut anteriorly.
  • 11. Anterior Curvature:  It Follows antero- posterior curve of vertebral column through neck, thorax (posterior mediastinum) & upper abdomen
  • 12. Midline infront of prevertebral fasia Then inclines slightly to left. (enters thoracic inlet) again at T5 midline at T7 again deviates to left Passes infront of thoracic aorta.
  • 13. Site Vertebral Level Distance from central incisor Cricopharynx C 6 15 cm Aortic arch T 4 25 cm Lt main bronchus T 5 28 cm Oesophageal hiatus T 10 40 cm
  • 14.  The most common site of oesophageal impaction is at the thoracic inlet  The cricopharyngeus sling at C6 is also at this level and may "catch" a foreign body.  About 70% of blunt foreign bodies that lodge in the oesophagus do so at this location.  Another 15% become lodged at the mid oesophagus, in the region where the aortic arch and carina overlap the oesophagus on chest radiograph.  The remaining 15% become lodged at the lower oesophageal sphincter (LES) at the gastroesophageal junction.
  • 15. Topographically, there are three distinct regions: cervical, thoracic, and abdominal. 1.CERVICAL OESOPHAGUS: extends from the pharyngoesophageal junction to the suprasternal notch. about 4 to 5 cm long.
  • 16. 2.THORACIC OESOPHAGUS:  Extends from the suprasternal notchdiaphragmatic hiatus. Passes posterior to the trachea, the tracheal bifurcation, and the left main stem bronchus.
  • 17. The esophagus lies posterior and to the right of the aortic arch at the T4 vertebral level. the esophagus lies anteriorly to the aorta from the level of T8 until the diaphragmatic hiatus
  • 18. 3.ABDOMINAL OESOPHAGUS: Extends from the diaphragmatic hiatusorifice of the cardia of the stomach. Forms a truncated cone, about 1 cm long.
  • 19. Two high-pressure zones prevent the backflow of food: The upper and The lower esophageal sphincter.
  • 20.  Between pharynx and the cervical oesophagus.  Located at C5-C6 level.  The UES is a musculocartilaginous structure.  This is formed by fibers of cricopharyngeus, part of the inferior constrictor, which encircles the oesophageal entrance
  • 21. The cricopharyngeus muscle is a striated muscle. produces maximum tension in the A.P direction and less tension in lateral direction. composed of a mixture of fast- and slow-twitch fibres. This muscle forms the main component of UES.
  • 22. The lower esophageal sphincter is a high-pressure zone located where the esophagus merges with the stomach. Mean pressure here is approx. 8mm Hg.
  • 23. The LES is a functional unit composed of an intrinsic and an extrinsic component. INTRINSICoesophagel muscle fibers and is under neurohormonal influence EXTRINSICdiaphragm muscle.
  • 24. The endoscopic localization of the LES is different from the manometric localization. The endoscopic localizationdetermined by changes in the esophageal mucosal transition from nonstratified squamous esophageal epithelium to the gastric mucosa “Z- line”or B ring. Functional location of LES is 3 cm distal to the Z-line.
  • 26. Bulbous distension of distal oesophagusvestibule. It corresponds to manometrically defined LES.
  • 27. 1.Attachment of cranial end of oesophagus  Longitudinal muscle attaches to the lamina of the cricoid cartilage by means of a tendon – CRICOOESOPHAGEAL tendon 2.Attachment of tubular oesophagus  Attached to trachea, pleura, and prevertebral fascia by several fibrous strands
  • 28. 3.Attachments of distal end  Two diaphragmatic crura  Phrenooesophageal ligament Phernooesophageal ligament:  Created by blending of the subdiaphragmatic fascia and the endothoracic fascia  Also known as LIMER‟S FASCIA, or ALLISON‟S MEMBRANE  Two sheaths- upper inserts into oesophageal tunica muscularis and submucosa: lower inserts into gastric serosa, and mesentry
  • 30. 1.Cervical part  Trachea anteriorly  RLN, carotid sheath with contents & lower pole of thyroid glands laterally  Posteriorly prevertebral fascia  Thoracic duct lies behind the left border
  • 31. 2.Thoracic part In superior mediastinum  Oesophagus lies between trachea and vertebral column  It enters posterior mediastinum behind aortic arch at T4  Left recurrent laryngeal nerve & thoracic duct are related posteriorly  Laterally:  left: arch of aorta, vagus nerve, left subclavian artery, pleura  Right: azygous vein, pleura
  • 32. Thoracic part in posterior mediastinum  Anteriorly Tracheal bifurcation , pericardium right pulmonary artery, tracheobronchial lymph nodes  Posteriorly vertebral column, long cervical muscles, right posterior intercostal arteries, thoracic duct , azygous vein and two hemi azygous veins & thoracic aorta inferiorly.  On left is descending thoracic aorta, pleura  On right, right pleura and azygous vein  Vagal fibers lie in close relation left vagus anteriorly and right vagus posteriorly
  • 33. 3.Abdominal oesophagus  Lies slightly left of median plane  Related to the posterior surface of the left lobe of the liver  Right border is continuous with lesser curvature & left ends in the cardiac notch  Covered by peritoneum anteriorly  Posteriorly lie left crus of diaphragm and left inferior phrenic artery
  • 34. Four coats from outside inwards: 1. Fibrous coat (adventitia) 2. Muscular coat (muscularis propria) 3. Submucous coat 4. Mucous coat
  • 35. Layer of loose, supportive fibrous tissue Conducts major vessels & nerves longitudinally A serosa formed by visceral peritoneum replaces adventitia of intra-abdominal segment of oesophagus
  • 36. External longitudinal muscle Internal circular muscle Parasympathetic ganglia forming Auerbach's nerve plexus lies b/w them Upper 1/3: striated muscle Middle 1/3: striated & smooth Lower 1/3: smooth muscle
  • 38. Loose supporting areolar tissue contains: Serous and mucous glands Blood vessels Lymphatic channels Parasympathetic ganglia forming Meissner's nerve plexus
  • 39. 1. Epithelium: non-keratinizing stratified sqamous epithelium 2. Lamina propria: loose areolar tissue with lymphoid aggregates 3. Muscularis mucosae: produces local movement of mucosa & helps in drainage of gland secretions
  • 40. Pink, smooth, protective oesophageal mucosa leads to red, mamillated, secretory gastric mucosa across Z (zigzag) line at 38-40 cm from incisors. Higher Z line seen in Barret‟s esophagus.
  • 41.  The rich arterial supply of the esophagus is segmental .  Branches of the inferior thyroid arteryUES and cervical esophagus.  Paired aortic esophageal arteries or terminal branches of bronchial arteriesthoracic esophagus.  The left gastric artery and a branch of the left phrenic arteryLES and the most distal segment of the esophagus.
  • 42.  The venous supply is also segmental.  From the dense submucosal plexus the venous blood drains into the superior vena cava.  veins of proximal and distal esophagus azygous system.  Veins of mid oesophaguscollaterals of left gastric vein.
  • 43.  The lymphatics from the proximal 1/3rddrain into the deep cervical LNs subsequently into the thoracic duct.  Middle 1/3rd  into superior and posterior mediastinal nodes.  Distal 1/3rd gastric and celiac lymph nodes. Surgical Importance:  Submucosal lymphatics explain why tumours may extend long distance before obstructing lumen  May also explain high recurrence rates  Bidirectional lymph flow may explain retrograde tumour seeding if flow is blocked
  • 44.  Parasympathetic nerve supply: (SENSORY,MOTOR,SECR ETOMOTOR)  Upper ½rec.laryngeal nerve.  Lower ½oesophageal plexus formed by the 2 vagus plexus.  The sympathetic nerve supply(VASOMOTOR)  Upper ½by fibres from mid cervical ganglion.  Lower ½directly from upper four thoracic ganglia.
  • 45.  The ganglia that lie between the longitudinal and the circular layersmyenteric or Auerbach's plexus.  That lie in the submucosa form the submucous or Meissner's plexus.  Auerbach's plexusregulates contraction of the outer muscle layers.  Meissner's plexusregulates secretion and the peristaltic contractions of the muscularis mucosae.