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Pituitary Gland (pg 4)
Pituitary Gland (pg 4)
• The size of a pea
• Hangs below the hypothalamus of the brain.
Sits in the “Turk’s saddle” of the sphenoid
bone
• Controlled by the hypothalamus
• Consists of 2 lobes: The anterior pituitary is
made of glandular tissue and the posterior
pituitary is made of nervous tissue
Anterior pituitary (Adenohypophysis)
• Makes 6 hormones, 4 of which are tropic
hormones (meaning they stimulate other
endocrine glands)
• Called the “master endocrine gland”
• Controlled by hormones produced by the
hypothalamus
1. Growth Hormone (GH): Stimulates target
cells to grow in size and to divide
Target tissue: Bones and skeletal muscles
1. Growth Hormone (GH): Stimulates target cells to
grow in size and to divide
Target tissue: Bones and skeletal muscles
Hyposecretion (not enough hormone) Pituitary
dwarfism
Hypersecretion (too much hormone) in childhood
Gigantism
Hypersecretion in adulthood Acromegaly (large
facial bones, hands, and feet)
2. Prolactin (PRL): Promotes development of
milk glands in breasts and stimulates milk
production after childbirth. No known
function in men.
3. Adrenocorticotropic Hormone (ACTH):
Regulates hormone production of the cortex
portion of the adrenal glands. Stimulates
melanocytes in the skin to produce more
melanin.
4. Thyroid stimulating hormone: Controls
growth and activity of the thyroid gland
5 & 6. Gonadotropic hormones: Regulate hormonal
activity of the gonads (testes and ovaries)
5. Follicle-stimulating hormone (FSH)
Females: Stimulates follicle development in the
ovaries
Males: Stimulates sperm development
6. Luteinizing hormone (LH)
Females: Triggers ovulation
Males: Stimulates testosterone production by the
interstitial cells of the testes
Posterior Pituitary (Neurohypophysis)
• Does not make the hormones it releases. They
are made by the hypothalamus and the
posterior pituitary stores them
Posterior Pituitary (Neurohypophysis)
• Does not make the hormones it releases. They
are made by the hypothalamus and the
posterior pituitary stores them
• Controlled by nerve impulses from the
hypothalamus
Posterior Pituitary (Neurohypophysis)
• Does not make the hormones it releases. They
are made by the hypothalamus and the
posterior pituitary stores them
• Controlled by nerve impulses from the
hypothalamus
• Releases 2 hormones
1. Oxytocin: Stimulates contractions of the
uterus during childbirth and ejection of milk
during nursing
2. Antidiuretic hormone (ADH): Causes the
kidneys to reabsorb more water, decreasing
urine volume. Increases blood pressure by
causing constriction of the arterioles.
Secretion of ADH is inhibited by alcohol
Hyposecretion diabetes insipidus
Hypersecretionhigh blood pressure
Diagram (pg 5)

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Pituitary gland

  • 2. Pituitary Gland (pg 4) • The size of a pea • Hangs below the hypothalamus of the brain. Sits in the “Turk’s saddle” of the sphenoid bone • Controlled by the hypothalamus • Consists of 2 lobes: The anterior pituitary is made of glandular tissue and the posterior pituitary is made of nervous tissue
  • 3. Anterior pituitary (Adenohypophysis) • Makes 6 hormones, 4 of which are tropic hormones (meaning they stimulate other endocrine glands) • Called the “master endocrine gland” • Controlled by hormones produced by the hypothalamus
  • 4. 1. Growth Hormone (GH): Stimulates target cells to grow in size and to divide Target tissue: Bones and skeletal muscles
  • 5. 1. Growth Hormone (GH): Stimulates target cells to grow in size and to divide Target tissue: Bones and skeletal muscles Hyposecretion (not enough hormone) Pituitary dwarfism Hypersecretion (too much hormone) in childhood Gigantism Hypersecretion in adulthood Acromegaly (large facial bones, hands, and feet)
  • 6. 2. Prolactin (PRL): Promotes development of milk glands in breasts and stimulates milk production after childbirth. No known function in men.
  • 7. 3. Adrenocorticotropic Hormone (ACTH): Regulates hormone production of the cortex portion of the adrenal glands. Stimulates melanocytes in the skin to produce more melanin.
  • 8. 4. Thyroid stimulating hormone: Controls growth and activity of the thyroid gland
  • 9. 5 & 6. Gonadotropic hormones: Regulate hormonal activity of the gonads (testes and ovaries) 5. Follicle-stimulating hormone (FSH) Females: Stimulates follicle development in the ovaries Males: Stimulates sperm development 6. Luteinizing hormone (LH) Females: Triggers ovulation Males: Stimulates testosterone production by the interstitial cells of the testes
  • 10. Posterior Pituitary (Neurohypophysis) • Does not make the hormones it releases. They are made by the hypothalamus and the posterior pituitary stores them
  • 11. Posterior Pituitary (Neurohypophysis) • Does not make the hormones it releases. They are made by the hypothalamus and the posterior pituitary stores them • Controlled by nerve impulses from the hypothalamus
  • 12. Posterior Pituitary (Neurohypophysis) • Does not make the hormones it releases. They are made by the hypothalamus and the posterior pituitary stores them • Controlled by nerve impulses from the hypothalamus • Releases 2 hormones
  • 13. 1. Oxytocin: Stimulates contractions of the uterus during childbirth and ejection of milk during nursing
  • 14. 2. Antidiuretic hormone (ADH): Causes the kidneys to reabsorb more water, decreasing urine volume. Increases blood pressure by causing constriction of the arterioles. Secretion of ADH is inhibited by alcohol Hyposecretion diabetes insipidus Hypersecretionhigh blood pressure