Human embryonic development

T
SSttaaggeess ooff PPrreeggnnaannccyy aanndd 
DDeevveellooppmmeenntt 
· Fertilization 
· Embryonic development - Cleavage 
· Fetal - Differentiation 
· Growth – Development 
· Childbirth
FFeerrttiilliizzaattiioonn 
· The egg is viable for 12 to 24 hours after ovulation 
· Sperm are viable for 12 to 48 hours after ejaculation 
· Sperm cells must make their way to the uterine tube for 
fertilization to be possible
ZYGOTE 
1. The sperm and egg join to form a zygote: the first 
cell of a new individual. 
2. Zygote results of the fusion of DNA from sperm and 
egg 
2. Fertilization occurs in the Fallopian Tubes 
3. The zygote begins rapid mitotic cell division 
4. Beginning of human development
ZYGOTE 
Only thirty hours after conception 
Size: no larger than the head of a pin 
1. Still rapidly dividing 
2. The zygote floats down from the fallopian tube 
and towards the uterus
CClleeaavvaaggee 
Cleavage is the mitotic division of cells in the early embryo
MORULA 
CClleeaavvaaggee 
About 96 hours after fertilization. 
This picture shows a MORULA, a solid 
ball of 32 cells that resembles a raspberry.
BLASTULA 
1. A ball of more that 64 cells surrounding a fluid-filled 
cavity (the blastocele) 
1. Blastula is produced by the repeated mitotic division of a 
zygote 
CClleeaavvaaggee 
Five days after fertilization
CClleeaavvaaggee 
IImmppllaannttaattiioonn 
BLASTOCYST 
1. The fastening of the embryo to the wall of the uterus 
is called implantation 
2. Implantation occurs seven days after fertilization 
3. Implantation takes places in the uterus.
TThhee EEmmbbrryyoo 
· The embryo is the developmental stage from the 
start of cleavage until the ninth week 
· The embryo first undergoes division without growth 
· The embryo enters the uterus at the 16-cell state 
· The embryo floats free in the uterus temporarily 
· Uterine secretions are used for nourishment
DDiiffffeerreennttiiaattiioonn 
GGaassttrruullaattiioonn 
Gastrulation involves a series of cell migrations to positions where 
they will form the three primary cell layers. 
•Ectoderm forms the outer layer. Ectoderm forms skin, hair, 
sweat glands, epithelium, brain and nervous system. 
•Endoderm forms the inner layer. The endoderm forms 
digestive, respiratory systems, liver, pancreas, all bladder, and 
endocrine glands such as thyroid and parathyroid glands. 
•Mesoderm forms the middle layer. The mesoderm forms 
body muscles, cartilage, bone, blood, reproductive system 
organs and kidneys
DDeevveellooppmmeenntt ffrroomm OOvvuullaattiioonn ttoo 
IImmppllaannttaattiioonn
EMBRYO 
0.5 cms 
20 days after fertilization 
DDiiffffeerreennttiiaattiioonn 
•Embryo begins to form organs during 
the third week. 
•Cannot tell if it is human or other 
vertebrate. Tall visible.
EMBRYO 
1 months 
0.6 cms 
DDiiffffeerreennttiiaattiioonn 
• Ears, nose and eyes not visible 
• Small arm and leg buds, backbone seen 
• Heart beats.
FETUS 
2 months 
3 cms 
DDiiffffeerreennttiiaattiioonn 
• During the second month most of the major 
organ systems form, limb buds develop. 
• Limbs distinct with fingers and toes bones 
begin to form, eyes far apart. 
• The embryo becomes a fetus by the seventh 
week.
DDiiffffeerreennttiiaattiioonn 
· All organ systems are 
formed by the end of the 
eighth week 
· Activities of the fetus are 
growth and organ 
specialization 
· A stage of tremendous 
growth and change in 
appearance 
Fetus at nine weeks 
3 cm
FETUS 
2 months 
3 cms 
DDiiffffeerreennttiiaattiioonn 
•Beginning the eighth week, the sexually 
neutral fetus activates gene pathways for 
sex determination, forming testes in XY 
fetuses and ovaries in XX fetuses. 
•External genitalia develop.
GGrroowwtthh 
FETUS 
4 months 
18 cms 
•Head enlarged, face has human feature. 
•The fetus increases in size during this 
trimester, and bony parts of the skeleton begin 
to form. 
•Fetal movements can be felt by the mother..
FETUS 
7 months 
About 40 cms 
GGrroowwtthh 
· During this trimester the fetus increases in size. 
· Circulatory and respiratory systems mature in 
preparation for air breathing. 
· Fetal growth during this time uses large parts of 
its mother's protein and calcium intake. 
· Maternal antibodies pass to the fetus during the 
last month, conferring temporary immunity.
GGrroowwtthh 
FETUS 
About 50 cms 
9 months 
• Fat under skin, smooth wrinkles. 
• Nails on fingers and toes completely formed. 
• Baby at term.
Fertilization Cleavage Differentiation Growth 
Zygote Morula Blastocyst Gastrula Embryo 
Fertilization Mitosis Implantation Neuralization 
Uterine 
Wall 
Fallopian 
tubes 
Fallopian Uterine 
Uterine 
Uterine 
Vagina 
tubes 
Wall 
Wall 
Wall 
Fetus Fetus 
Childbirth
Human embryonic development
CChhiillddbbiirrtthh ((PPaarrttiittiioonn)) 
· Labor – the series of events that expel 
the infant from the uterus 
· Initiation of labor 
· Estrogen levels rise 
· Uterine contractions begin 
·The placenta releases prostaglandins 
·Oxytocin is released by the pituitary 
·Combination of these hormones produces 
contractions
DDeevveellooppmmeennttaall AAssppeeccttss ooff tthhee 
RReepprroodduuccttiivvee SSyysstteemm 
Slide 
16.64a 
· Gender is determined at fertilization 
·Males have XY sex chromosomes 
·Females have XX sex chromosomes 
· Gonads do not begin to form until the 
eighth week 
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Sexually Transmitted Diseases 
(STDs): Worldwide Problem 
• Bacterial: gonorrhea, syphilis, chlamydia 
• Viral: HIV, hepatitis B, genital herpes, genital 
warts 
• Other: yeasts (Candida), protozoan 
(Trichomonas), arthropod (pubic lice) 
• Prevention 
–Strategies: choose partner wisely, communicate, use 
suitable barriers, get tested and treated
1 sur 24

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Human embryonic development

  • 1. SSttaaggeess ooff PPrreeggnnaannccyy aanndd DDeevveellooppmmeenntt · Fertilization · Embryonic development - Cleavage · Fetal - Differentiation · Growth – Development · Childbirth
  • 2. FFeerrttiilliizzaattiioonn · The egg is viable for 12 to 24 hours after ovulation · Sperm are viable for 12 to 48 hours after ejaculation · Sperm cells must make their way to the uterine tube for fertilization to be possible
  • 3. ZYGOTE 1. The sperm and egg join to form a zygote: the first cell of a new individual. 2. Zygote results of the fusion of DNA from sperm and egg 2. Fertilization occurs in the Fallopian Tubes 3. The zygote begins rapid mitotic cell division 4. Beginning of human development
  • 4. ZYGOTE Only thirty hours after conception Size: no larger than the head of a pin 1. Still rapidly dividing 2. The zygote floats down from the fallopian tube and towards the uterus
  • 5. CClleeaavvaaggee Cleavage is the mitotic division of cells in the early embryo
  • 6. MORULA CClleeaavvaaggee About 96 hours after fertilization. This picture shows a MORULA, a solid ball of 32 cells that resembles a raspberry.
  • 7. BLASTULA 1. A ball of more that 64 cells surrounding a fluid-filled cavity (the blastocele) 1. Blastula is produced by the repeated mitotic division of a zygote CClleeaavvaaggee Five days after fertilization
  • 8. CClleeaavvaaggee IImmppllaannttaattiioonn BLASTOCYST 1. The fastening of the embryo to the wall of the uterus is called implantation 2. Implantation occurs seven days after fertilization 3. Implantation takes places in the uterus.
  • 9. TThhee EEmmbbrryyoo · The embryo is the developmental stage from the start of cleavage until the ninth week · The embryo first undergoes division without growth · The embryo enters the uterus at the 16-cell state · The embryo floats free in the uterus temporarily · Uterine secretions are used for nourishment
  • 10. DDiiffffeerreennttiiaattiioonn GGaassttrruullaattiioonn Gastrulation involves a series of cell migrations to positions where they will form the three primary cell layers. •Ectoderm forms the outer layer. Ectoderm forms skin, hair, sweat glands, epithelium, brain and nervous system. •Endoderm forms the inner layer. The endoderm forms digestive, respiratory systems, liver, pancreas, all bladder, and endocrine glands such as thyroid and parathyroid glands. •Mesoderm forms the middle layer. The mesoderm forms body muscles, cartilage, bone, blood, reproductive system organs and kidneys
  • 11. DDeevveellooppmmeenntt ffrroomm OOvvuullaattiioonn ttoo IImmppllaannttaattiioonn
  • 12. EMBRYO 0.5 cms 20 days after fertilization DDiiffffeerreennttiiaattiioonn •Embryo begins to form organs during the third week. •Cannot tell if it is human or other vertebrate. Tall visible.
  • 13. EMBRYO 1 months 0.6 cms DDiiffffeerreennttiiaattiioonn • Ears, nose and eyes not visible • Small arm and leg buds, backbone seen • Heart beats.
  • 14. FETUS 2 months 3 cms DDiiffffeerreennttiiaattiioonn • During the second month most of the major organ systems form, limb buds develop. • Limbs distinct with fingers and toes bones begin to form, eyes far apart. • The embryo becomes a fetus by the seventh week.
  • 15. DDiiffffeerreennttiiaattiioonn · All organ systems are formed by the end of the eighth week · Activities of the fetus are growth and organ specialization · A stage of tremendous growth and change in appearance Fetus at nine weeks 3 cm
  • 16. FETUS 2 months 3 cms DDiiffffeerreennttiiaattiioonn •Beginning the eighth week, the sexually neutral fetus activates gene pathways for sex determination, forming testes in XY fetuses and ovaries in XX fetuses. •External genitalia develop.
  • 17. GGrroowwtthh FETUS 4 months 18 cms •Head enlarged, face has human feature. •The fetus increases in size during this trimester, and bony parts of the skeleton begin to form. •Fetal movements can be felt by the mother..
  • 18. FETUS 7 months About 40 cms GGrroowwtthh · During this trimester the fetus increases in size. · Circulatory and respiratory systems mature in preparation for air breathing. · Fetal growth during this time uses large parts of its mother's protein and calcium intake. · Maternal antibodies pass to the fetus during the last month, conferring temporary immunity.
  • 19. GGrroowwtthh FETUS About 50 cms 9 months • Fat under skin, smooth wrinkles. • Nails on fingers and toes completely formed. • Baby at term.
  • 20. Fertilization Cleavage Differentiation Growth Zygote Morula Blastocyst Gastrula Embryo Fertilization Mitosis Implantation Neuralization Uterine Wall Fallopian tubes Fallopian Uterine Uterine Uterine Vagina tubes Wall Wall Wall Fetus Fetus Childbirth
  • 22. CChhiillddbbiirrtthh ((PPaarrttiittiioonn)) · Labor – the series of events that expel the infant from the uterus · Initiation of labor · Estrogen levels rise · Uterine contractions begin ·The placenta releases prostaglandins ·Oxytocin is released by the pituitary ·Combination of these hormones produces contractions
  • 23. DDeevveellooppmmeennttaall AAssppeeccttss ooff tthhee RReepprroodduuccttiivvee SSyysstteemm Slide 16.64a · Gender is determined at fertilization ·Males have XY sex chromosomes ·Females have XX sex chromosomes · Gonads do not begin to form until the eighth week Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 24. Sexually Transmitted Diseases (STDs): Worldwide Problem • Bacterial: gonorrhea, syphilis, chlamydia • Viral: HIV, hepatitis B, genital herpes, genital warts • Other: yeasts (Candida), protozoan (Trichomonas), arthropod (pubic lice) • Prevention –Strategies: choose partner wisely, communicate, use suitable barriers, get tested and treated