Antidepressants Tca Ssri

ANTIDEPRESSANTS ,[object Object],[object Object]

Definitions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Depression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Neurobiological theory of depression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Therapy of depression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],I. Tricyclic Antidepressants (TCAs) imipramine

Mode of action ,[object Object],[object Object],[object Object]

Pharmacological action ,[object Object],[object Object],[object Object]

Classification ,[object Object],[object Object],[object Object]

Classification ,[object Object],[object Object],[object Object],[object Object]

Most important TCAs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

INDICATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Contraindication

Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object]

Drug interaction ,[object Object],[object Object],[object Object],[object Object],[object Object]

Drug Dose ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Adverse Effects Pharmacological Action Adverse Effect Muscarinic receptor Blockage/ Anticholinergic ,[object Object],[object Object],[object Object],ᾴ1 Adrenoceptor blockade ,[object Object],[object Object],Histamine H1 receptor Blockade Drowsiness, Weight Gain Membrane stabilizing properties Cardiac conduction defects, Cardiac arrythmia, Seizures Others Rash, Oedema, Leukopenia, Elevated liver enzymes

Teratogenic effects ,[object Object]

Toxic Effects ,[object Object],[object Object],[object Object]

Management of toxicity ,[object Object],[object Object],[object Object],[object Object],[object Object]

Newer Drugs ,[object Object],[object Object]

II. Selective Serotonin Re-uptake Inhibito r s (SSRI) ,[object Object],[object Object],[object Object],[object Object],[object Object]

Most important SSRI ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Adverse effects ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Serotonin Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object]

SSRI discontinuation syndrome ,[object Object],[object Object],[object Object]

Antidepressants Tca Ssri

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