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Breast  Reconstruction: Decision Making  Surgical Planning Michael J. Miller, M.D. Professor of Surgery Director, Division of Plastic Surgery The Ohio State University
Lifetime Probability of Developing Cancer Source:DevCan: Probability of Developing or Dying of Cancer Soft ware, Version 5.1 Statistical Research and Applications Branch, NCI, 2003. http://srab.cancer.gov/devcan 1 in 59 Ovary 1 in 57 NH-Lymphoma 1 in38 Uterine corpus 1 in 18 Colon and rectum 1 in 17 Lung and bronchus 1 in 7 Breast 1 in 3 All Sites Risk Site
Why Breast Reconstruction?
Mastectomy/ No Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Decreased Quality of Life
Reconstruction Options Immediate Delayed Timing Technique Tissue Tissue + Implant Implants alone
Delayed Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Immediate Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Reconstruction Options Immediate Delayed Timing Technique Tissue Tissue + Implant Implants alone
Breast Reconstruction Methods UTMDACC 1990 - 2000
Implant Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Implant Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Two-Stage Implant Reconstruction Pre-op Full Expansion Final Result
Acellular Dermal Matrix (AlloDerm ® ) Zienowicz RJ. Karacaoglu E.  Plastic & Reconstructive Surgery . 120(2):373-81, 2007
Zienowicz RJ. Karacaoglu E.  Plastic & Reconstructive Surgery . 120(2):373-81, 2007
Preminger BA. et. al.  Annals of Plastic Surgery.  60(5):510-3, 2008.
“ Well, this is a fine mess …”
[object Object],“ Well, this is a fine mess …”
[object Object],[object Object],“ Well, this is a fine mess …”
Breast Implantation ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Breast Implant Devices
Breast Implantation ,[object Object],[object Object],[object Object],[object Object],[object Object],Direct Injections
Silicone Implant Alternatives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Complications
Pre-Silicone Implant Era ,[object Object],[object Object],[object Object],[object Object],Non-rigorous trials… What was known:
Silicone Breast Implants ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Silicone Breast Implants ,[object Object]
Prior to 1970’s:  little regulation or oversight…
FDA Device Regulation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Value + = ?
Clinical Value ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Nelson EC. et al.  Joint Commission Journal on Quality Improvement. 22(4):243-58, 1996
Clinical Value ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Pre-1991 acceptable + Value Score
Clinical Value ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Pre-1991 acceptable Post-1991 + Value Score acceptable ? ? ? ? ? ?
Clinical Value
Medical Device Safety Risk Benefit
Silicon Gel Breast Implants ,[object Object],[object Object],[object Object],[object Object],[object Object],2006- Silicone Gel implants return to the U.S. market
[object Object],[object Object]
Reconstruction Options Immediate Delayed Timing Technique Tissue Tissue + Implant Implants alone
Skin Sparing Mastectomy
Skin Sparing Mastectomy The  ablative surgeon  begins the reconstruction!
Skin-Sparing Mastectomy Incisions only for:  - Nipple and Areola   - Access to the axilla - Biopsy scars   - Skin areas “at risk”
Skin Sparing Mastectomy
Pre-op Post-op Skin Sparing Mastectomy
Skin Sparing Mastectomy Mastectomy skin flap necrosis
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Skin-Sparing Mastectomy
Oncologic Safety of SSM vs. CM Local Recurrence Rate (T2 tumors) Kroll 104/SSM 271/CM Carlson 327/SSM 188/CM Simmons 77/SSM 154/CM SSM CM 15% 12% 9% 6% 3% 0%
Skin Sparing Mastectomy ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],Skin Sparing Mastectomy
Latissimus Dorsi + Implant
 
Latissimus Dorsi Flap + Implant Pre-op Post-op Donor site scar
LD flap- Endoscopic Harvest Post-op. ( 3/1/2005) Pre-op. ( 1/13/2004)
LD flap- Endoscopic Harvest Pre-op Post-op
Reconstruction Options Immediate Delayed Timing Technique Tissue Tissue + Implant Implants alone
Autologous Tissue Reconstruction
Pedicled TRAM
Pedicled TRAM ,[object Object],Download illustrations from Moon and Taylor
Microvascular Tissue Transfer
Microsurgical Breast Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Perforator Flaps ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
5/13/2008
5/29/2008
CT Angiogram Analysis
7/23/2008 7/23/2008
7/8/2008 7/23/2008 7/23/2008
CT Angiogram Analysis: Vessel Selection
9/2/2008 9/2/2008 Autologous Reconstruction: I-Gap Candidate
CT Angiogram Analysis: I-Gap Planning
9/18/2008
Autologous Tissue Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Autologous Tissue Reconstruction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ideal Abdominal Tissue Candidate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adjunct Procedures ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
5/29/2007 10/2/2007 1/29/2008
Nipple Reconstruction 3 cm 4 cm
Nipple Reconstruction 3 cm 4 cm
Nipple Reconstruction
Nipple-Areola Micropigmentation
Final Results ,[object Object],[object Object],[object Object],[object Object]
Thank you! University Hospital James Cancer Hospital The Ohio State University Plastic Surgery …  to restore and make whole
 
Skin-Sparing Mastectomy Frozen section control of margins
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Skin-Sparing Mastectomy
Local/Regional Recurrence*after  Skin-Sparing Mastectomy  Immediate Flap Reconstruction  (Stage ll) * Median follow-up 5.4 years **  None with stage 0 or stage I breast  cancer
Oncologic Safety of SSM vs. CM Local Recurrence Rate (T2 tumors) Kroll 104/SSM 271/CM Carlson 327/SSM 188/CM Simmons 77/SSM 154/CM SSM CM 15% 12% 9% 6% 3% 0%
Local Recurrences after Skin-Sparing Mastectomy and Immediate Reconstruction Group Number Pts. Local Recurrences (%) All 104 6.7 T1 61 3.3 T2 43 11.6 Black’s grade I* 31 12.9 Black’s grade II 48 6.3 Black’s grade III 6 0.0 *The lower the grade, the more anaplastic the tumor Ann Surg Oncol 4:193-197,1997
Regional recurrence after skin-spring mastectomy is a function of the biology of the tumor and stage of disease
Detection and Management of Local Recurrence Following SSM MDACC Experience ,[object Object],[object Object],[object Object],[object Object]
Local Recurrence Following SSM MDACC Experience ,[object Object],[object Object],[object Object],[object Object]
Imaging of Local Recurrence ,[object Object],[object Object],[object Object],[object Object]
 
Distant Relapse and Overall Survival ,[object Object],[object Object],[object Object],[object Object]
Local Control and Outcome by Treatment Treatment # Pts. Local Control  Alive, NED Local only 3 100% 100% (Surgery or Surgery + RT) Systemic only 5 60% 40% Local and  15 86% 71% Systemic
Local Control and Outcome by Treatment Local Only Systemic Only Local & Systemic Local Control Alive, NED 100% 80% 60% 40% 20% 0%
Skin Sparing Mastectomy ,[object Object],[object Object],[object Object]
[object Object],[object Object],Skin Sparing Mastectomy
MDACC Recommendations ,[object Object],[object Object]
MDACC Recommendations ,[object Object]
Reservations Regarding  Skin-Sparing Mastectomy ,[object Object],[object Object],[object Object]

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2008 breast reconstruction (aust)

Editor's Notes

  1. They are able to achieve wonderful results in reconstruction like these patients who have had breast reconstruction following mastectomy, where patient quality of life is markedly increased from an emotional, physical, and cosmesis standpoint. Despite results like these , clinical limitations in reconstruction following tumor removal are often realized.
  2. Guta Percha- a natural resin rubber from a malaysian tree called the Isonandra Gutta tree Terylene, a polyester fiber, the first wholly synthetic fibre invented in the United Kingdom.