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The Infection Chain™ Concept
Piglet Approach System Approach
Looking for the root of a problem
Chain of the infection in Epidemiology field:
Individual (host)approach
10 September
2013
4
Image courtesy of:
The pig production cycle or “chain”
10 September
2013
5
Production Chain / Infection Chain
10 September
2013
6
“Infection Chain” of swine pathogens
10 September
2013
7
Production flow / infection / prevention
“Chain”
10 September
2013
8
PRRS…the example
10 September
2013
9
Role of Vaccine – Immunity for Control
PRRSv in Growing Pigs
• Vaccine provides protective immunity that can mitigate the
consequences of PRRSv infection
• The common benefit of vaccines is to improve herd health,
which in turn improves economic return
• Meta-Analysis of 16 Modified Live PRRS Vaccination Challenge Studies; M.Roof
et. al., Emerg Swine Dis Symp, 2007
• Growth Performance Improvement and Mortality Reductions Derived from a PRRS
Large-Scale Control Project in the U.S.; J. Angulo, et.al., IPVS, 2012
Statement of the Problem:
•PRRS instability in the breeding herd
• Defined as evidence of
PRRSv circulation and
transmission vertically and/or
horizontally
• Can cause reproductive
problems w/ biologic &
economic impact
• Can lead to weaning of
PRRSv positive piglets w/
biologic & economic impact
• PRRSv Control or Elimination;
D.Holtkamp, George Young Conf.,
2012
• Assessment of economic impact of
PRRSv on U.S. pork producers; D.
Holtkamp et.al., JSHAP, 2013
Production flow / infection / prevention
“Chain”
10 September
2013
12
Chain Thinking
Production
Chain
Infection
Chain™
Prevention
Chain™
10 September
2013
13
Chain Thinking

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Dr. Brian Payne - Infection Chain Concept

  • 3. Looking for the root of a problem
  • 4. Chain of the infection in Epidemiology field: Individual (host)approach 10 September 2013 4 Image courtesy of:
  • 5. The pig production cycle or “chain” 10 September 2013 5
  • 6. Production Chain / Infection Chain 10 September 2013 6
  • 7. “Infection Chain” of swine pathogens 10 September 2013 7
  • 8. Production flow / infection / prevention “Chain” 10 September 2013 8
  • 10. Role of Vaccine – Immunity for Control PRRSv in Growing Pigs • Vaccine provides protective immunity that can mitigate the consequences of PRRSv infection • The common benefit of vaccines is to improve herd health, which in turn improves economic return • Meta-Analysis of 16 Modified Live PRRS Vaccination Challenge Studies; M.Roof et. al., Emerg Swine Dis Symp, 2007 • Growth Performance Improvement and Mortality Reductions Derived from a PRRS Large-Scale Control Project in the U.S.; J. Angulo, et.al., IPVS, 2012
  • 11. Statement of the Problem: •PRRS instability in the breeding herd • Defined as evidence of PRRSv circulation and transmission vertically and/or horizontally • Can cause reproductive problems w/ biologic & economic impact • Can lead to weaning of PRRSv positive piglets w/ biologic & economic impact • PRRSv Control or Elimination; D.Holtkamp, George Young Conf., 2012 • Assessment of economic impact of PRRSv on U.S. pork producers; D. Holtkamp et.al., JSHAP, 2013
  • 12. Production flow / infection / prevention “Chain” 10 September 2013 12