SlideShare une entreprise Scribd logo
1  sur  15
Télécharger pour lire hors ligne
Translating discovery science into improved
health through technological innovation
An Integrated Life Sciences Campus
UHB QE Hospital
Future location Children’s Hospital
NIHR-WT CRF
Advanced Therapy Facility
Royal Centre Defence Medicine
Trauma Research Centre

Institute of Biomedical Research

Centre for Translational
Inflammation Research

Institute Translational Medicine

Medical School
CRUK Cancer Centre

Public Health Research
Primary Care

University of Birmingham
IBR

WM AHSN
PATIENT &
Adoption
POPULATION
Education
HEALTH
Clinical Trials
Digital Technology
Wealth Creation
Integrated Care

CLAHRC

DISCOVERY SCIENCE

EFFECTIVENESS

HEALTH ECONOMICS

BHP

IMPLEMENTATION

CLINICAL
TRIALS

CLINICAL
OBSERVATIONS
EXPERIMENTAL
MEDICINE

CRC TU
BCTU
PCTU

NIHR
WT CRF
Focussed Research Strategy with
World Leading Outputs
CLINICAL ACADEMIC GROUPS
STRATIFIED MEDICINE
SCIENTIFIC
DISCOVERY

CLINICAL TRIALS
SURGERY, DEVICES, DIAGNOSTICS
ENABLING TECHNOLOGIES
COMMERCIALISATION
EDUCATION
PATIENT & PUBLIC INVOLVEMENT

CHRONIC
INFLAMMATORY
DISEASE

CANCER

ENDOCRINOLOGY
& METABOLISM

PATIENT
BENEFIT
REGIONAL
DEVELOPMENT
GLOBAL
IMPACT
Translational Research Underpinned by
Nationally Funded Centres
Chronic Inflammation
MRC CENTRE
IMMUNE
REGULATION

MRC-ARUK
CENTRE M-S
AGEING

ARUK RA
CENTRE of
EXCELLENCE

NIHR BRU
LIVER
DISEASE

NIHR TRP
Joint and
Inflammatory
Disease

NIHR Wellcome
Trust CRF

ARUK
BEAT RA

NIHR
CLAHRC WM

Endocrine & Metabolism

Cancer
CRUK
CANCER
CENTRE

CRUK TRIALS
UNIT

ECMC

LLR CENTRE

EXPERIMENTAL
CANCER
CENTRE

CLINICAL
HEMATOLOGY

TAP

NIHR
TRAUMA
HTC

NIHR TRC
ENDOCRINE
NEOPLASIA

NIHR
TRAUMA
CENTRE

HEALING
FOUNDATION
CENTRE FOR
BURNS

NIHR TRC
RARE
DISEASES

CRUK
Technology
Hub

ERDF
Biomedical
Innovation Hub

NICE External
Assessment
Centre

EPSRC Multidisciplinary
Assessment of
Technology Centre for
Healthcare (MATCH)
Digital Technology Supports Excellence in Care

EDUCATION
SERVICE IMPROVEMENT
CLINICAL AUDIT

RESEARCH
Research Advances Embedded in Education
and Training to all Health Workers
• Clinical academic training
– Inspire student programme
– Royal College of Surgeons trainee programme
– Clinical fellows embedded in NIHRWT CRF
• New models
– Empowering NHS Consultants to deliver research
• Multidisciplinary – Allied Health Professionals
– Common CPD, CME, e-learning platforms across BHP
– Centre for Research in Medical & Dental Education
The Institute of Translational Medicine (ITM)
- co-locating all components of an effective
translational infrastructure
• UK Government £12m
• BHP £12m
• To open June 2015

A UNIQUE TRANSLATIONAL FACILITY WITH
STRATIFIED MEDICINE AT ITS CORE
Inflammation research in Birmingham
EATC
BEAT-RA
TRP’s

MRC Centre
Theme 3

Inflammation
Biology

MRC-ABPI

SSfH

CRF
IRF
ARUK-MRC
Ageing
Centre for Translational Inflammation Research

MRC Centre for Immune
Regulation
The Birmingham Inflammation Group
CVS
Brain
e.g. MS
Teeth
Liver
Liver

Process
Driven
Pathology

Eye
Lung
Lung
Skin

Joint
Joint Kidney
Current Situation
In Chronic Inflammation

•Fragmentation
•Duplication
•Disease specific funding
•Short term
•Diagnosis to pathology

Birmingham Inflammation Group

•Integration
•Multidisciplinary
•Process specific funding
•Durability
•Pathology to Diagnosis
Inflammation Research Facility
CVS
Brain
e.g. MS
Teeth
Liver
Liver

Eye
Lung

Shared
Cohorts
And IT
(co-morbidity)

Lung
Skin

Joint
Joint Kidney
Current Situation
In Chronic Inflammation

•Primary-secondary care split
•No core data set
•No information on co-morbidity
•Lack of real world data

IRF
(supported by WT CRF)

•Integration across 1ry and 2ry
•Core data set
•Respiratory, CVS, metabolic, periodontal
•Within NHS Research Clinics
Experimental Arthritis in Birmingham
• Unique stromal expertise
• Highly focused basic science and expanding early arthritis
cohorts
• Direct access to patient tissue samples
• Discrete stromal target discovery programmes
• Multiple pre-clinical animal models
• Internal and Industry therapeutic candidates
Markers
Epigenetics
SSFH

Protein
expression
In vitro
function

Periodontal

cohort

samples

target
discovery

validation

pre-clinical
studies

cohort:
therapy
Operational Partnership
UHBFT Queen Elizabeth Hospital

Centre for Translational
Inflammation

Integrated clinical and laboratory space
WTCRF satellite (IRF)
NIHR Trauma Centre

ARUK/MRC CoE in MSK ageing research
ARUK EATC (BEAT-RA)
Translational Research Partnership
ARUK CoE in Pathogenesis of RA
Strategy for UK Life Sciences

UK wide strategy
• Reduce bureaucracy
• £310m for stratified medicine
and commercial research
• Opt out for research data
• Encourage industry
engagement
• Stimulate economic growth

Contenu connexe

Tendances

EPAD 2017 - Lydia Makaroff
EPAD 2017 - Lydia MakaroffEPAD 2017 - Lydia Makaroff
EPAD 2017 - Lydia MakaroffMarc van Gurp
 
UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...
UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...
UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...CTSI at UCSF
 
The Role of Patients & their Challenges in Clinical Trials
The Role of Patients & their Challenges in Clinical TrialsThe Role of Patients & their Challenges in Clinical Trials
The Role of Patients & their Challenges in Clinical TrialsKathi Apostolidis
 
EPAD 2017 - Tit Albreht
EPAD 2017 - Tit AlbrehtEPAD 2017 - Tit Albreht
EPAD 2017 - Tit AlbrehtMarc van Gurp
 
EPAD 2017 - Dominik Berthold
EPAD 2017 - Dominik BertholdEPAD 2017 - Dominik Berthold
EPAD 2017 - Dominik BertholdMarc van Gurp
 
Finres - Antimicrobial Resistance Database
Finres - Antimicrobial Resistance DatabaseFinres - Antimicrobial Resistance Database
Finres - Antimicrobial Resistance DatabaseTHL
 
International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...The King's Fund
 
Precision oncology ncabr kibbe oct 2017
Precision oncology ncabr kibbe oct 2017Precision oncology ncabr kibbe oct 2017
Precision oncology ncabr kibbe oct 2017Warren Kibbe
 
Presentation Faculty of Health Sciences
Presentation Faculty of Health SciencesPresentation Faculty of Health Sciences
Presentation Faculty of Health SciencesAnika Mackenroth
 
Transforming the NHS through genomic and personalised medicine, pop up uni, 1...
Transforming the NHS through genomic and personalised medicine, pop up uni, 1...Transforming the NHS through genomic and personalised medicine, pop up uni, 1...
Transforming the NHS through genomic and personalised medicine, pop up uni, 1...NHS England
 
International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...The King's Fund
 
IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016
IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016
IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016Guide to PHARMACOLOGY
 
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"CTSI at UCSF
 

Tendances (20)

EPAD 2017 - Lydia Makaroff
EPAD 2017 - Lydia MakaroffEPAD 2017 - Lydia Makaroff
EPAD 2017 - Lydia Makaroff
 
cancertipsheet
cancertipsheetcancertipsheet
cancertipsheet
 
PMED: APPM Workshop: Data & Analytics in Precision Oncology- Warren Kibbe, Ma...
PMED: APPM Workshop: Data & Analytics in Precision Oncology- Warren Kibbe, Ma...PMED: APPM Workshop: Data & Analytics in Precision Oncology- Warren Kibbe, Ma...
PMED: APPM Workshop: Data & Analytics in Precision Oncology- Warren Kibbe, Ma...
 
UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...
UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...
UCSF Informatics Day 2014 - Robert Nussbaum, "The Genomic Medicine Initiative...
 
The Role of Patients & their Challenges in Clinical Trials
The Role of Patients & their Challenges in Clinical TrialsThe Role of Patients & their Challenges in Clinical Trials
The Role of Patients & their Challenges in Clinical Trials
 
EPAD 2017 - Tit Albreht
EPAD 2017 - Tit AlbrehtEPAD 2017 - Tit Albreht
EPAD 2017 - Tit Albreht
 
EPAD 2017 - Dominik Berthold
EPAD 2017 - Dominik BertholdEPAD 2017 - Dominik Berthold
EPAD 2017 - Dominik Berthold
 
Finres - Antimicrobial Resistance Database
Finres - Antimicrobial Resistance DatabaseFinres - Antimicrobial Resistance Database
Finres - Antimicrobial Resistance Database
 
08 sigve nakken ncgc
08 sigve nakken ncgc08 sigve nakken ncgc
08 sigve nakken ncgc
 
GtoImmPdb_flash_poster_presentation
GtoImmPdb_flash_poster_presentationGtoImmPdb_flash_poster_presentation
GtoImmPdb_flash_poster_presentation
 
KI_Booklet (1)
KI_Booklet (1)KI_Booklet (1)
KI_Booklet (1)
 
International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...
 
CV
CVCV
CV
 
Precision oncology ncabr kibbe oct 2017
Precision oncology ncabr kibbe oct 2017Precision oncology ncabr kibbe oct 2017
Precision oncology ncabr kibbe oct 2017
 
Presentation Faculty of Health Sciences
Presentation Faculty of Health SciencesPresentation Faculty of Health Sciences
Presentation Faculty of Health Sciences
 
Transforming the NHS through genomic and personalised medicine, pop up uni, 1...
Transforming the NHS through genomic and personalised medicine, pop up uni, 1...Transforming the NHS through genomic and personalised medicine, pop up uni, 1...
Transforming the NHS through genomic and personalised medicine, pop up uni, 1...
 
International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...International digital health and care congress 2014 - Breakouts: Friday, Sess...
International digital health and care congress 2014 - Breakouts: Friday, Sess...
 
Introduction to the Faculty of Health Sciences
Introduction to the Faculty of Health SciencesIntroduction to the Faculty of Health Sciences
Introduction to the Faculty of Health Sciences
 
IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016
IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016
IUPHAR Guide to IMMUNOPHARMACOLOGY Poster - Pharmacology 2016
 
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"
 

Similaire à BCCT Showcase - chris buckley

Towards a National Learning Health System - Aziz Sheikh
Towards a National Learning Health System - Aziz SheikhTowards a National Learning Health System - Aziz Sheikh
Towards a National Learning Health System - Aziz SheikhNIHR CLAHRC West Midlands
 
Kevin Dean Digital Health Assembly 2015
Kevin Dean Digital Health Assembly 2015 Kevin Dean Digital Health Assembly 2015
Kevin Dean Digital Health Assembly 2015 DHA2015
 
EuroBioForum 2013 - Day 1 | Greame Boyle
EuroBioForum 2013 - Day 1 | Greame BoyleEuroBioForum 2013 - Day 1 | Greame Boyle
EuroBioForum 2013 - Day 1 | Greame BoyleEuroBioForum
 
Hinxton Poster 2010 - NIHR Programme
Hinxton Poster 2010 - NIHR Programme Hinxton Poster 2010 - NIHR Programme
Hinxton Poster 2010 - NIHR Programme Mike Messenger
 
UK Diagnostics Summit 2019
UK Diagnostics Summit 2019UK Diagnostics Summit 2019
UK Diagnostics Summit 20194 All of Us
 
The vision, priorities & approach for ucl partners AHSN
The vision, priorities & approach for ucl partners AHSNThe vision, priorities & approach for ucl partners AHSN
The vision, priorities & approach for ucl partners AHSNPM Society
 
Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...
Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...
Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...Kate Barlow
 
Colin dayan commercial research in cardiovascular disease
Colin dayan commercial research in cardiovascular diseaseColin dayan commercial research in cardiovascular disease
Colin dayan commercial research in cardiovascular diseaseangewatkins
 
In-Vitro-Diagnostics- Agenda
In-Vitro-Diagnostics- AgendaIn-Vitro-Diagnostics- Agenda
In-Vitro-Diagnostics- AgendaTony Couch
 
Roc ipposi dec2015 challenges and opportunities for clinical research
Roc ipposi dec2015 challenges and opportunities for clinical researchRoc ipposi dec2015 challenges and opportunities for clinical research
Roc ipposi dec2015 challenges and opportunities for clinical researchipposi
 
Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...
Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...
Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...ipposi
 
Ed Millensted - 100,00 Genomes Project
Ed Millensted - 100,00 Genomes ProjectEd Millensted - 100,00 Genomes Project
Ed Millensted - 100,00 Genomes ProjectInnovation Agency
 
The Scottish Ecosystem for Precision Medicine
The Scottish Ecosystem for Precision MedicineThe Scottish Ecosystem for Precision Medicine
The Scottish Ecosystem for Precision MedicineHEHTAslides
 
Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...
Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...
Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...Health Innovation Wessex
 
Declan Mulkeen - Increasing the impact of MRC research
Declan Mulkeen - Increasing the impact of MRC research  Declan Mulkeen - Increasing the impact of MRC research
Declan Mulkeen - Increasing the impact of MRC research Medical Research Council
 
Life Sciences Overview Pdf
Life Sciences Overview PdfLife Sciences Overview Pdf
Life Sciences Overview PdfDKhan01
 
Stroke prevention services - quality & safety indicators
Stroke prevention services - quality & safety indicatorsStroke prevention services - quality & safety indicators
Stroke prevention services - quality & safety indicatorsHelicon Health
 
mike durkin collaborative launch event oct 2014
mike durkin collaborative launch event oct 2014mike durkin collaborative launch event oct 2014
mike durkin collaborative launch event oct 2014NHS Improving Quality
 

Similaire à BCCT Showcase - chris buckley (20)

Towards a National Learning Health System - Aziz Sheikh
Towards a National Learning Health System - Aziz SheikhTowards a National Learning Health System - Aziz Sheikh
Towards a National Learning Health System - Aziz Sheikh
 
Kevin Dean Digital Health Assembly 2015
Kevin Dean Digital Health Assembly 2015 Kevin Dean Digital Health Assembly 2015
Kevin Dean Digital Health Assembly 2015
 
EuroBioForum 2013 - Day 1 | Greame Boyle
EuroBioForum 2013 - Day 1 | Greame BoyleEuroBioForum 2013 - Day 1 | Greame Boyle
EuroBioForum 2013 - Day 1 | Greame Boyle
 
Hinxton Poster 2010 - NIHR Programme
Hinxton Poster 2010 - NIHR Programme Hinxton Poster 2010 - NIHR Programme
Hinxton Poster 2010 - NIHR Programme
 
UK Diagnostics Summit 2019
UK Diagnostics Summit 2019UK Diagnostics Summit 2019
UK Diagnostics Summit 2019
 
NIHR partnering with industry
NIHR partnering with industryNIHR partnering with industry
NIHR partnering with industry
 
The vision, priorities & approach for ucl partners AHSN
The vision, priorities & approach for ucl partners AHSNThe vision, priorities & approach for ucl partners AHSN
The vision, priorities & approach for ucl partners AHSN
 
Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...
Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...
Challenges and Opportunities for Digital PCR in the CLIA Laboratory of the Mo...
 
Colin dayan commercial research in cardiovascular disease
Colin dayan commercial research in cardiovascular diseaseColin dayan commercial research in cardiovascular disease
Colin dayan commercial research in cardiovascular disease
 
In-Vitro-Diagnostics- Agenda
In-Vitro-Diagnostics- AgendaIn-Vitro-Diagnostics- Agenda
In-Vitro-Diagnostics- Agenda
 
Roc ipposi dec2015 challenges and opportunities for clinical research
Roc ipposi dec2015 challenges and opportunities for clinical researchRoc ipposi dec2015 challenges and opportunities for clinical research
Roc ipposi dec2015 challenges and opportunities for clinical research
 
Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...
Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...
Patients Driving Health Innovation - Dr Abaigeal Jackson CF Registry - Octobe...
 
Ed Millensted - 100,00 Genomes Project
Ed Millensted - 100,00 Genomes ProjectEd Millensted - 100,00 Genomes Project
Ed Millensted - 100,00 Genomes Project
 
The Scottish Ecosystem for Precision Medicine
The Scottish Ecosystem for Precision MedicineThe Scottish Ecosystem for Precision Medicine
The Scottish Ecosystem for Precision Medicine
 
The role of clinical research in securing the future of the industry in Ireland
The role of clinical research in securing the future of the industry in IrelandThe role of clinical research in securing the future of the industry in Ireland
The role of clinical research in securing the future of the industry in Ireland
 
Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...
Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...
Wessex GMC The 100,000 Genomes Project in Wessex: Progress and integration in...
 
Declan Mulkeen - Increasing the impact of MRC research
Declan Mulkeen - Increasing the impact of MRC research  Declan Mulkeen - Increasing the impact of MRC research
Declan Mulkeen - Increasing the impact of MRC research
 
Life Sciences Overview Pdf
Life Sciences Overview PdfLife Sciences Overview Pdf
Life Sciences Overview Pdf
 
Stroke prevention services - quality & safety indicators
Stroke prevention services - quality & safety indicatorsStroke prevention services - quality & safety indicators
Stroke prevention services - quality & safety indicators
 
mike durkin collaborative launch event oct 2014
mike durkin collaborative launch event oct 2014mike durkin collaborative launch event oct 2014
mike durkin collaborative launch event oct 2014
 

Dernier

SGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdf
SGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdfSGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdf
SGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdfHongBiThi1
 
ayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologypptayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologypptPradnya Wadekar
 
EXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung functionEXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung functionkrishnareddy157915
 
"Radical excision of DIE in subferile women with deep infiltrating endometrio...
"Radical excision of DIE in subferile women with deep infiltrating endometrio..."Radical excision of DIE in subferile women with deep infiltrating endometrio...
"Radical excision of DIE in subferile women with deep infiltrating endometrio...Sujoy Dasgupta
 
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...Shubhanshu Gaurav
 
CONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdf
CONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdfCONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdf
CONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdfDolisha Warbi
 
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.aarjukhadka22
 
Trustworthiness of AI based predictions Aachen 2024
Trustworthiness of AI based predictions Aachen 2024Trustworthiness of AI based predictions Aachen 2024
Trustworthiness of AI based predictions Aachen 2024EwoutSteyerberg1
 
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptxANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptxWINCY THIRUMURUGAN
 
Neurological history taking (2024) .
Neurological  history  taking  (2024)  .Neurological  history  taking  (2024)  .
Neurological history taking (2024) .Mohamed Rizk Khodair
 
SGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA .pdf
SGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA    .pdfSGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA    .pdf
SGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA .pdfHongBiThi1
 
DNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptx
DNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptxDNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptx
DNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptxMAsifAhmad
 
How to cure cirrhosis and chronic hepatitis naturally
How to cure cirrhosis and chronic hepatitis naturallyHow to cure cirrhosis and chronic hepatitis naturally
How to cure cirrhosis and chronic hepatitis naturallyZurück zum Ursprung
 
High-Performance Thin-Layer Chromatography (HPTLC)
High-Performance Thin-Layer Chromatography (HPTLC)High-Performance Thin-Layer Chromatography (HPTLC)
High-Performance Thin-Layer Chromatography (HPTLC)kishan singh tomar
 
SGK ĐIỆN GIẬT ĐHYHN RẤT LÀ HAY TUYỆT VỜI.pdf
SGK ĐIỆN GIẬT ĐHYHN        RẤT LÀ HAY TUYỆT VỜI.pdfSGK ĐIỆN GIẬT ĐHYHN        RẤT LÀ HAY TUYỆT VỜI.pdf
SGK ĐIỆN GIẬT ĐHYHN RẤT LÀ HAY TUYỆT VỜI.pdfHongBiThi1
 
Breast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptx
Breast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptxBreast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptx
Breast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptxNaveenkumar267201
 
Red Blood Cells_anemia & polycythemia.pdf
Red Blood Cells_anemia & polycythemia.pdfRed Blood Cells_anemia & polycythemia.pdf
Red Blood Cells_anemia & polycythemia.pdfMedicoseAcademics
 

Dernier (20)

Rheumatoid arthritis Part 1, case based approach with application of the late...
Rheumatoid arthritis Part 1, case based approach with application of the late...Rheumatoid arthritis Part 1, case based approach with application of the late...
Rheumatoid arthritis Part 1, case based approach with application of the late...
 
SGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdf
SGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdfSGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdf
SGK LEUKEMIA KINH DÒNG BẠCH CÂU HẠT HAY.pdf
 
ayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologypptayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologyppt
 
EXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung functionEXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung function
 
"Radical excision of DIE in subferile women with deep infiltrating endometrio...
"Radical excision of DIE in subferile women with deep infiltrating endometrio..."Radical excision of DIE in subferile women with deep infiltrating endometrio...
"Radical excision of DIE in subferile women with deep infiltrating endometrio...
 
How to master Steroid (glucocorticoids) prescription, different scenarios, ca...
How to master Steroid (glucocorticoids) prescription, different scenarios, ca...How to master Steroid (glucocorticoids) prescription, different scenarios, ca...
How to master Steroid (glucocorticoids) prescription, different scenarios, ca...
 
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
 
CONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdf
CONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdfCONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdf
CONNECTIVE TISSUE (ANATOMY AND PHYSIOLOGY).pdf
 
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
 
Trustworthiness of AI based predictions Aachen 2024
Trustworthiness of AI based predictions Aachen 2024Trustworthiness of AI based predictions Aachen 2024
Trustworthiness of AI based predictions Aachen 2024
 
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptxANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptx
 
Neurological history taking (2024) .
Neurological  history  taking  (2024)  .Neurological  history  taking  (2024)  .
Neurological history taking (2024) .
 
American College of physicians ACP high value care recommendations in rheumat...
American College of physicians ACP high value care recommendations in rheumat...American College of physicians ACP high value care recommendations in rheumat...
American College of physicians ACP high value care recommendations in rheumat...
 
SGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA .pdf
SGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA    .pdfSGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA    .pdf
SGK NGẠT NƯỚC ĐHYHN RẤT LÀ HAY NHA .pdf
 
DNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptx
DNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptxDNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptx
DNA nucleotides Blast in NCBI and Phylogeny using MEGA Xi.pptx
 
How to cure cirrhosis and chronic hepatitis naturally
How to cure cirrhosis and chronic hepatitis naturallyHow to cure cirrhosis and chronic hepatitis naturally
How to cure cirrhosis and chronic hepatitis naturally
 
High-Performance Thin-Layer Chromatography (HPTLC)
High-Performance Thin-Layer Chromatography (HPTLC)High-Performance Thin-Layer Chromatography (HPTLC)
High-Performance Thin-Layer Chromatography (HPTLC)
 
SGK ĐIỆN GIẬT ĐHYHN RẤT LÀ HAY TUYỆT VỜI.pdf
SGK ĐIỆN GIẬT ĐHYHN        RẤT LÀ HAY TUYỆT VỜI.pdfSGK ĐIỆN GIẬT ĐHYHN        RẤT LÀ HAY TUYỆT VỜI.pdf
SGK ĐIỆN GIẬT ĐHYHN RẤT LÀ HAY TUYỆT VỜI.pdf
 
Breast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptx
Breast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptxBreast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptx
Breast cancer -ONCO IN MEDICAL AND SURGICAL NURSING.pptx
 
Red Blood Cells_anemia & polycythemia.pdf
Red Blood Cells_anemia & polycythemia.pdfRed Blood Cells_anemia & polycythemia.pdf
Red Blood Cells_anemia & polycythemia.pdf
 

BCCT Showcase - chris buckley

  • 1. Translating discovery science into improved health through technological innovation
  • 2. An Integrated Life Sciences Campus
  • 3. UHB QE Hospital Future location Children’s Hospital NIHR-WT CRF Advanced Therapy Facility Royal Centre Defence Medicine Trauma Research Centre Institute of Biomedical Research Centre for Translational Inflammation Research Institute Translational Medicine Medical School CRUK Cancer Centre Public Health Research Primary Care University of Birmingham
  • 4. IBR WM AHSN PATIENT & Adoption POPULATION Education HEALTH Clinical Trials Digital Technology Wealth Creation Integrated Care CLAHRC DISCOVERY SCIENCE EFFECTIVENESS HEALTH ECONOMICS BHP IMPLEMENTATION CLINICAL TRIALS CLINICAL OBSERVATIONS EXPERIMENTAL MEDICINE CRC TU BCTU PCTU NIHR WT CRF
  • 5. Focussed Research Strategy with World Leading Outputs CLINICAL ACADEMIC GROUPS STRATIFIED MEDICINE SCIENTIFIC DISCOVERY CLINICAL TRIALS SURGERY, DEVICES, DIAGNOSTICS ENABLING TECHNOLOGIES COMMERCIALISATION EDUCATION PATIENT & PUBLIC INVOLVEMENT CHRONIC INFLAMMATORY DISEASE CANCER ENDOCRINOLOGY & METABOLISM PATIENT BENEFIT REGIONAL DEVELOPMENT GLOBAL IMPACT
  • 6. Translational Research Underpinned by Nationally Funded Centres Chronic Inflammation MRC CENTRE IMMUNE REGULATION MRC-ARUK CENTRE M-S AGEING ARUK RA CENTRE of EXCELLENCE NIHR BRU LIVER DISEASE NIHR TRP Joint and Inflammatory Disease NIHR Wellcome Trust CRF ARUK BEAT RA NIHR CLAHRC WM Endocrine & Metabolism Cancer CRUK CANCER CENTRE CRUK TRIALS UNIT ECMC LLR CENTRE EXPERIMENTAL CANCER CENTRE CLINICAL HEMATOLOGY TAP NIHR TRAUMA HTC NIHR TRC ENDOCRINE NEOPLASIA NIHR TRAUMA CENTRE HEALING FOUNDATION CENTRE FOR BURNS NIHR TRC RARE DISEASES CRUK Technology Hub ERDF Biomedical Innovation Hub NICE External Assessment Centre EPSRC Multidisciplinary Assessment of Technology Centre for Healthcare (MATCH)
  • 7. Digital Technology Supports Excellence in Care EDUCATION SERVICE IMPROVEMENT CLINICAL AUDIT RESEARCH
  • 8. Research Advances Embedded in Education and Training to all Health Workers • Clinical academic training – Inspire student programme – Royal College of Surgeons trainee programme – Clinical fellows embedded in NIHRWT CRF • New models – Empowering NHS Consultants to deliver research • Multidisciplinary – Allied Health Professionals – Common CPD, CME, e-learning platforms across BHP – Centre for Research in Medical & Dental Education
  • 9. The Institute of Translational Medicine (ITM) - co-locating all components of an effective translational infrastructure • UK Government £12m • BHP £12m • To open June 2015 A UNIQUE TRANSLATIONAL FACILITY WITH STRATIFIED MEDICINE AT ITS CORE
  • 10. Inflammation research in Birmingham EATC BEAT-RA TRP’s MRC Centre Theme 3 Inflammation Biology MRC-ABPI SSfH CRF IRF ARUK-MRC Ageing Centre for Translational Inflammation Research MRC Centre for Immune Regulation
  • 11. The Birmingham Inflammation Group CVS Brain e.g. MS Teeth Liver Liver Process Driven Pathology Eye Lung Lung Skin Joint Joint Kidney Current Situation In Chronic Inflammation •Fragmentation •Duplication •Disease specific funding •Short term •Diagnosis to pathology Birmingham Inflammation Group •Integration •Multidisciplinary •Process specific funding •Durability •Pathology to Diagnosis
  • 12. Inflammation Research Facility CVS Brain e.g. MS Teeth Liver Liver Eye Lung Shared Cohorts And IT (co-morbidity) Lung Skin Joint Joint Kidney Current Situation In Chronic Inflammation •Primary-secondary care split •No core data set •No information on co-morbidity •Lack of real world data IRF (supported by WT CRF) •Integration across 1ry and 2ry •Core data set •Respiratory, CVS, metabolic, periodontal •Within NHS Research Clinics
  • 13. Experimental Arthritis in Birmingham • Unique stromal expertise • Highly focused basic science and expanding early arthritis cohorts • Direct access to patient tissue samples • Discrete stromal target discovery programmes • Multiple pre-clinical animal models • Internal and Industry therapeutic candidates Markers Epigenetics SSFH Protein expression In vitro function Periodontal cohort samples target discovery validation pre-clinical studies cohort: therapy
  • 14. Operational Partnership UHBFT Queen Elizabeth Hospital Centre for Translational Inflammation Integrated clinical and laboratory space WTCRF satellite (IRF) NIHR Trauma Centre ARUK/MRC CoE in MSK ageing research ARUK EATC (BEAT-RA) Translational Research Partnership ARUK CoE in Pathogenesis of RA
  • 15. Strategy for UK Life Sciences UK wide strategy • Reduce bureaucracy • £310m for stratified medicine and commercial research • Opt out for research data • Encourage industry engagement • Stimulate economic growth