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The purpose of open access is to ensure that
scientific knowledge can be used and built-
upon by anyone
Open access is a means to a goal – not a goal
in itself
What if we could freely get to all the essential
knowledge contained in scientific articles,
without those articles necessarily being open
access?
Nano-publication
in Science & Medicine



Jan Velterop – EUA Autumn Conference – Gießen – 9 October 2009
Current knowledge
     transfer
Current knowledge
     transfer




                    Signal to noise
                        ratio?
Current knowledge transfer – an analogy: needle transport
Shouldn’t we focus on the ‘needles’
and learn how to reason with the
essence of available knowledge?
If we did, we could have:

– access to far more knowledge than now
– access to knowledge in our own language
  irrespective of the language it was first
  written in
Every problem has its solution
Every solution has its problem
What is needed?
What do we have to do?
What do we still have to overcome?
from Term

to Concept
42
The Ogden Triangle

                        Concept


                                  The relations between the corners:

                                      1.   Object evokes Concept (in writer’s or speaker’s mind)
                                      2.   Writer/speaker uses Token to refer to Object
                                      3.   Token evokes Concept (in reader‘s or listener's mind)
                                      4.   Reader/listener refers Token back to Object



                       ‘cancer’
Term (token)                        Object
 ‘cancer’
 Malignant Neoplasms
 Krebskrankheit
 C0-265
 Etc.
Terms – representing concepts
Terms – representing concepts




CAPN3_00265                    LGMD2A                 Jan Velterop


CAPN3:c.62G>A                  nCL-1                  Johannes Velterop


CAPN3:p.(Gly21Glu)             Calpain p94            JJM Velterop


dbSNP:rs28364364               Calcium-activated      J Velterop
                               neutral proteinase 3

C0000053                       CANP 3
Terms are language-dependent

Concepts are language-independent
from Concept

to Statement
Concept
Concept
Concept
Introducing Triples

     Concept
     Concept
     Concept
Statements are Concept ‘Triples’


Jan Velterop              presented            these slides




CAPN3_00265               has pathogenicity    LGMD2A




Dystrophin                interacts with       SNT3




Calpain-3                 has GO annotation    proteosome
                                               endopeptidase
                                               activity
Concept ‘Triples’ are language independent




Jan Velterop              presented           these slides


Johannes Velterop         vertoonde           deze dia’s


JJM Velterop              zeigte              diese Transparantien


J Velterop                présentait          cettes diapositives
Annotating

Statements
Statements are only taken seriously when they
  can show all, or most, of these attributes:
Statements are only taken seriously when they
  can show all, or most, of these attributes:
              authorship
              context
              strength of concept relation
              provenance
              condition
              directionality
              time stamp
              comments
Such annotated statements

           are
Such annotated statements

           are

   Nano-publications
What must a publication be?
What must a publication be?

Citeable and giving appropriate credit? – yes
What must a publication be?

Citeable and giving appropriate credit? – yes

Valuable to scientific progress and understanding? – yes
What must a publication be?

Citeable and giving appropriate credit? – yes

Valuable to scientific progress and understanding? – yes

Conveying knowledge? – yes
What must a publication be?

Citeable and giving appropriate credit? – yes

Valuable to scientific progress and understanding? – yes

Conveying knowledge? – yes

Full-length? – no
Triples                      Open Access

<triple><is><reference>
                                   open access triples benefit
<reference><is><open access>
                                   authors and publishers,
<reference><may be><cited>
                                   including traditional
<citation><benefits><author>
                                   publishers
<citation><benefits><publisher>



     Triples                      Languages
Triples                      Open Access

<triple><is><reference>
                                   open access triples benefit
<reference><is><open access>
                                   authors and publishers,
<reference><may be><cited>
                                   including traditional
<citation><benefits><author>
                                   publishers
<citation><benefits><publisher>



     Triples                      Languages
Triples   Open Access
          International Reach

Triples   Languages
What’s to be done?
De-PDF repository content
(or at least add XML or HTML versions)

Convert literature to nano-publications
it is cheap – current estimate ≈ ¢’s per kilo-character (≈ 1 typical research journal
page)

Share nano-publications (in an open triple store)
Start with biomedical (life science) content
simply because semantic concept methodologies are most advanced in that area
Contact me:
velterop@conceptweballiance.org

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Giessen October 9 09 Nano Publication

  • 1. The purpose of open access is to ensure that scientific knowledge can be used and built- upon by anyone
  • 2. Open access is a means to a goal – not a goal in itself
  • 3. What if we could freely get to all the essential knowledge contained in scientific articles, without those articles necessarily being open access?
  • 4. Nano-publication in Science & Medicine Jan Velterop – EUA Autumn Conference – Gießen – 9 October 2009
  • 5. Current knowledge transfer
  • 6. Current knowledge transfer Signal to noise ratio?
  • 7.
  • 8. Current knowledge transfer – an analogy: needle transport
  • 9. Shouldn’t we focus on the ‘needles’ and learn how to reason with the essence of available knowledge?
  • 10. If we did, we could have: – access to far more knowledge than now – access to knowledge in our own language irrespective of the language it was first written in
  • 11. Every problem has its solution
  • 12. Every solution has its problem
  • 13. What is needed? What do we have to do? What do we still have to overcome?
  • 15. 42
  • 16. The Ogden Triangle Concept The relations between the corners: 1. Object evokes Concept (in writer’s or speaker’s mind) 2. Writer/speaker uses Token to refer to Object 3. Token evokes Concept (in reader‘s or listener's mind) 4. Reader/listener refers Token back to Object ‘cancer’ Term (token) Object ‘cancer’ Malignant Neoplasms Krebskrankheit C0-265 Etc.
  • 18. Terms – representing concepts CAPN3_00265 LGMD2A Jan Velterop CAPN3:c.62G>A nCL-1 Johannes Velterop CAPN3:p.(Gly21Glu) Calpain p94 JJM Velterop dbSNP:rs28364364 Calcium-activated J Velterop neutral proteinase 3 C0000053 CANP 3
  • 19. Terms are language-dependent Concepts are language-independent
  • 21.
  • 23. Introducing Triples Concept Concept Concept
  • 24. Statements are Concept ‘Triples’ Jan Velterop presented these slides CAPN3_00265 has pathogenicity LGMD2A Dystrophin interacts with SNT3 Calpain-3 has GO annotation proteosome endopeptidase activity
  • 25. Concept ‘Triples’ are language independent Jan Velterop presented these slides Johannes Velterop vertoonde deze dia’s JJM Velterop zeigte diese Transparantien J Velterop présentait cettes diapositives
  • 27.
  • 28. Statements are only taken seriously when they can show all, or most, of these attributes:
  • 29. Statements are only taken seriously when they can show all, or most, of these attributes: authorship context strength of concept relation provenance condition directionality time stamp comments
  • 31. Such annotated statements are Nano-publications
  • 32. What must a publication be?
  • 33. What must a publication be? Citeable and giving appropriate credit? – yes
  • 34. What must a publication be? Citeable and giving appropriate credit? – yes Valuable to scientific progress and understanding? – yes
  • 35. What must a publication be? Citeable and giving appropriate credit? – yes Valuable to scientific progress and understanding? – yes Conveying knowledge? – yes
  • 36. What must a publication be? Citeable and giving appropriate credit? – yes Valuable to scientific progress and understanding? – yes Conveying knowledge? – yes Full-length? – no
  • 37. Triples Open Access <triple><is><reference> open access triples benefit <reference><is><open access> authors and publishers, <reference><may be><cited> including traditional <citation><benefits><author> publishers <citation><benefits><publisher> Triples Languages
  • 38. Triples Open Access <triple><is><reference> open access triples benefit <reference><is><open access> authors and publishers, <reference><may be><cited> including traditional <citation><benefits><author> publishers <citation><benefits><publisher> Triples Languages
  • 39. Triples Open Access International Reach Triples Languages
  • 40. What’s to be done? De-PDF repository content (or at least add XML or HTML versions) Convert literature to nano-publications it is cheap – current estimate ≈ ¢’s per kilo-character (≈ 1 typical research journal page) Share nano-publications (in an open triple store) Start with biomedical (life science) content simply because semantic concept methodologies are most advanced in that area