1. Poster List
2010
Elferink, M.G.L., Olinga P., van Leeuwen E.M., Bauerschmidt S., Polman J., Schoonen W.G., Heisterkamp
S.H., Groothuis G.M.M. (2010a). Gene expression analysis of precision cut human liver slices indicate
stable expression of ADME-Tox related genes. Eurotox, Barcelona
Elferink, M.G.L., Olinga P., van Leeuwen E.M., Bauerschmidt S., Polman J., Schoonen W.G., Heisterkamp
S.H., Groothuis G.M.M. (2010b). Gene expression analysis of precision cut human liver slices indicate
stable expression of ADME-Tox related genes. Gordon conference.
Vermeulen, N., Augustijn, A., Russel, F., Groothuis, G., Pieters, R., Water, van de B. Commandeur, J., Irth, H.,
Burg, van der B., Janssen, R., Joore, J., Brilleman, A., Emmen, H., Schoonen, W., and Koster, H. (2010).
Translational biomarkers for adverse drug reactions. TI Pharma Meeting, April, Utrecht.
2009
Bovee, T.F.H., Thevis, M., Schoonen, W.G.E.J., Weigel, S., and Nielen, M.W.F. (2009). Bioassay screening of
SERMs and SARMs in pharmacology, food supplements and sports doping. 4th International Symposium
on Recent Advances in Food Analysis (RAFA 2009), 4 th to 6th November, Prague, Czech Republic.
Gracanin, A., Sartorius, C.A., Koepfli, K.P., Wayne, R.K., Schoonen, W.G., and Mol, J.A. (2009). The fairy tail
of canine progesterone receptor. Gordon Conference, Hormone action in development and cancer. 26 th to
31th July, Holderness, United States.
Lauwers, A., Griffioen,G., Wera, S., Duhamel, H., Vandamme, N., Schoonen, W., and Westerink, W., (2009) A
yeast-based screening method for genotoxic and clastogenic compounds compatible with S9 metabolic
activation. 15th International Congress on In Vitro Toxicology, IVTIP 2009, 26 th October, Edegem (near
Antwerp), Belgium.
Schoonen, W.G.E.J., Westerink, W.M.A., Stevenson, J.C.R., and Horbach, G.J. (2009). RAD51C, Cystatin A,
p53, and Nrf2 luciferase-based reporter assays in metabolic competent HepG2 cells for the rapid
assessment of genotoxicity and oxidative stress in the early research phase. 46 th Congress of the European
Societies of Toxicology, EUROTOX2009, 13 th to 16th September, Dresden, Germany.
Westerink, W.M.A., Stevenson, J.C.R., Horbach, G.J. and Schoonen, W.G.E.J., (2009) .
The development of RAD51C, Cystatin A, P53 and Nrf2 luciferase reporter assays in metabolic competent
HepG2 cells for the assessment of mechanistic genotoxicity and of oxidative stress in the early research
phase. 18th Netherlands Society of Toxicology (NVT) Anniversary Meeting, NVT2009, 18 th and 19th June,
Veldhoven, The Netherlands.
Westerink, W.M.A., Stevenson, J.C.R., Horbach, G.J. and Schoonen, W.G.E.J., (2009) .
The development of RAD51C, Cystatin A, P53 and Nrf2 luciferase reporter assays in metabolic competent
HepG2 cells for the assessment of mechanistic genotoxicity and of oxidative stress in the early research
phase. INVITROM Meeting, 2009, 25th November, Edegem near Antwerp, Belgium.
2008
Lauwers, A., Griffioen,G., Wera, S., Duhamel, H., Vandamme, N., Schoonen, W., and Westerink, W., (2008) A
yeast-based screening method for genotoxic and clastogenic compounds compatible with S9 metabolic
activation. 15th International Congress on In Vitro Toxicology, ESTIV2008, 25 th to 28th September,
Stockholm, Sweden.
2007
Elferink, M.G.L., Olinga, P., Draaisma, A.L., Merema, M.T., Zeinstra, M., Bauerschmidt, S., Polman, J,
Schoonen, W.G. and Groothuis, G.G.M. (2007). Early markers of toxicity. Microarray analysis of
hepatotoxicity in vivo and in vitro. Pharmaceutical Sciences World Congress.
Elferink, M.G.L., Olinga, P., Draaisma, A.L., Merema, M.T., Bauerschmidt, S., Polman, J, Schoonen, W.G. and
Groothuis, G.G.M. (2007). Early markers of toxicity. Microarray analysis of hepatotoxicity in vivo and in
vitro. Eurotox, 7-10 October, 2007. Toxicology Letters 172, Suppl.1, S77.
Westerink, W.M.A., Stevenson, J.C.R. and Schoonen W.G.E.J. (2007) CYP1A induction and species differences
between human HepG2 and rat H4IIE cells. SSCT Salzau, Germany, 19-22 September, 2007.
Westerink, W.M.A., Stevenson, J.C.R. and Schoonen W.G.E.J. (2007) CYP1A induction and species differences
between human HepG2 and rat H4IIE cells. Amsterdam, The Netherlands, Eurotox, 7-10 October, 2007.
Toxicology Letters 172, Suppl. 1, S98.
Olinga, P., Elferink, M.G.L., Bauerschmidt, S., Polman, J., Schoonen, W.G.E.J., Draaisma, A.L., Merama, M.T.,
and Groothuis, G.M.M. (2007). Gene network analysis of acetaminophen and carbon tetrachloride treated

2. rat liver slices identifies hepatotoxicity mechanisms observed in vitro. Figon meeting, Lunteren 1-3
October 2007.
Olinga, P., Elferink, M.G.L., Bauerschmidt, S., Polman, J., Schoonen, W.G.E.J., Draaisma, A.L., Merama, M.T.,
and Groothuis, G.M.M. (2007). Gene network analysis of acetaminophen and carbon tetrachloride treated
rat liver slices identifies hepatotoxicity mechanisms observed in vitro. ISXX meeting 2007.
2006
Schoonen, W.G.E.J., Dijcks, F.A., de Gooyer, M.E., Peters, J.L.M. and Ederveen, A.G.H. (2006). Pharmacology
of selective agonists and antagonists for estrogen receptor α and : in vitro activities in CHO and MCF-7
cells and in vivo activity in rats on female lordosis behavior. J.Steroid Biochem. Mol. Biol. Seefeld,
Austria, 1-3 June 2006.
Westerink, W.M.A. and Schoonen, W.G.E.J. (2006a). Phase I enzyme levels in cryopreserved primary human
hepatocytes and HepG2 cells and their induction in HepG2 cells. Invitox, Oostende, 2-5 October 2006.
Westerink, W.M.A. and Schoonen, W.G.E.J. (2006b). Phase II enzyme levels in cryopreserved primary human
hepatocytes and HepG2 cells and their induction in HepG2 cells. Invitox, Oostende, 2-5 October 2006.
2005
Westerink, W. and Schoonen, W.G.E.J. (2005). Characterisation of phase I and II enzymes. Technician day,
Solvay-Duphar, Weesp, 24 may, 2005.
Westerink, W. and Schoonen, W.G.E.J. (2005). Characterisation of phase I and II enzymes. NVT meeting,
Organon, Oss, 7-8 June 2005.
Schoonen, W.G.E.J., Westerink, W.A.J., Horbach, G.J.M.J., Ploemen, J._P.H.T.M., Polman, J.E.M., and
Proustki, V. (2005). Toxicogenomics on rat and human liver. NVT meeting, Organon, Oss, 7-8 June 2005.
Schoonen W.G.E.J., Smit M.J., Zandberg P., Horbach G.J.M.J., Ploemen J._P.H.T.M., Kloks C.P.A.M.,
Mellema J.R., Thijssen-van Zuylen C., Vogels J.T.W.E., Tas C.A. and van Nesselrooij J.H.J. (2005).
Uniform procedure of 1H NMR analysis of rat urine with respect to toxico-metabonomics. NVT meeting,
Organon, Oss, 7-8 June 2005.
Lierop van, M.J.C., Vleuten, van M., Smets, R., Klop, H., Boerakker, R., Evers S., Schoonen, W., Dijkema, R.,
Dokter, W. (2005). The in vitro transrepression / transactivation profile of RU486 does not lead to a
dissociating glucocorticoid in vivo in mice. Keystone congres "Tissue-selective NR" (Sept 2005),
Breckenridge, Colorado, USA.
Schoonen, W.G.E.J., Smit, M.J., Zandberg, P., Horbach, G.J.M.J., Ploemen, J._P.H.T.M., Kloks, C.P.A.M.,
Mellema, J.R., Thijssen-van Zuylen, C., Vogels, J.T.W.E., Tas, C.A. and van Nesselrooij, J.H.J. (2005).
Uniform procedure of 1H NMR analysis of rat urine with respect to toxico-metabonomics. Eurotox 2005,
Krakau, September. Toxicology Letters 158, Suppl. 1, September 2005, P15-18.
Westerink, W.M.A. and Schoonen, W.G.E.J. (2005). Characterisation of phase I and II enzymes in HepG2 cells.
Figon Symposium, Lunteren, 4-5 Oct. 2005.
Schoonen W.G.E.J., Smit M.J., Zandberg P., Horbach G.J.M.J., Ploemen J._P.H.T.M., Kloks C.P.A.M.,
Mellema J.R., Thijssen-van Zuylen C., Vogels J.T.W.E., Tas C.A. and van Nesselrooij J.H.J. (2005).
Uniform procedure of 1H NMR analysis of rat urine with respect to toxico-metabonomics. Figon
Symposium, Lunteren, 4-5 Oct. 2005.
2003
Schoonen, W.G.E.J., Westerink, W.M.A., de Roos, J.A.D.M. and Débiton, E. (2003). Cytotoxic effects of 100
reference compounds on Hep G2 and HeLa cells. Florence (poster), Eurotox 2003.
2001
Schoonen, W.G.E.J., Westerink, W.M.A., de Roos, J.A.D.M. and Débiton, E. (2001). The effects of several toxic
reference compounds on Hep G2, HeLa, ECC-1 and CHO cells with Dichlorofluorescein diacetate,
monochlorobimane and Calcein-AM mechanistic assays. Washington (poster), In vitro toxicology.
Schoonen, W.G.E.J., Westerink, W.M.A., de Roos, J.A.D.M. and Débiton, E. (2001). Cytotoxic effects of
several toxic reference compounds on Hep G2, HeLa, ECC-1 and CHO cells with ATP-Lite, Cyto-Lite,
Alamar Blue and Hoechst 33342 assays. Washington (poster), In vitro toxicology.
2000
Schoonen, W.G.E.J., Deckers, G., Gooijer, de M.E., Ries de, R., Mathijssen-Mommers, G., Hamersma, H., and
Kloosterboer, H.J. (2000): Contraceptive progestins: Various 11-substituents combined with four 17-
substituents: 17-ethynyl, five- and six-membered spiromethylene ethers or six-membered spiromethylene
lactones. 14th International Symposium of the Journal of steroid Biochemistry & Molecular Biology
(poster), Quebec City, June 24-27, 2000. Abstract 40P.

3. 1999
Schoonen, W.G.E.J., Ries de, R.J.H., Joosten, J.W.H., Mathijssen-Mommers, G. and Kloosterboer, H.J. (1999):
Development of high throughput in vitro bioassays for steroid receptors. SBS conference Edinburgh
(poster), Sept 13-16, Scotland. Abstract.
1998
Schoonen, W.G.E.J., Mosselman, S. and Kar, S.A.T (1998): Comparison of human estrogen receptor  and ß in
binding and transactivation assays. Xth International congress on hormonal steroids. Quebec City (poster),
June 17-21, Canada. Abstract 3, Page 108.
1997
Schoonen, W.G.E.J., Ries de, R.J.H., de Gooyer, M.E., Deckers, G.H. and Kloosterboer, H.J. (1997). Hormonal
properties of norethisterone and its derivatives and the effect of a 7-methyl substitution. Symp.of J.
Steroid Biochem. and Molec. Biol. (poster), May, Monaco.
1996
Vermeulen G.J., Schoonen W.G.E.J., Kloosterboer H.J. (1996): The effect of antiprogestagens on the
interactions between progesterone receptor and DNA. Sex Hormones and Cancer (in association with the
Journal of Steroid Biochemistry and Molecular Biology), San Francisco USA (poster), 9-11 June 1996.
1995
Dijkema R., Teuwen R., Struik van der E., Wagenaars J.L., Ries de R.J.H., Joosten J.W.H. and Schoonen
W.G.E.J. (1995): Human progesterone receptor isoforms B and A: characterization of their individual
ligand binding properties in relation to transcriptional activation. Symposium of Steroid Biochemistry and
Molecular Biology (poster), May 1995, Berlin.
Hakola K., Haavistol A.M., Boogaart P. v.d., Mulders J., Schoonen W., Heyst J. v., Swolfs A., Casteren J. v.,
Huhtaniemi I., Kloosterboer H. (1995): Characterization of recombinant rat LH. Abstract (poster), annual
meeting of Finnish Endocrine Society.
Mosselman S., Teuwen R., Schoonen W. and Dijkema R. (1995): The use of CHO cells stably transfected with
the human androgen or progesterone receptor together with a reporter in profiling (anti)androgens and
(anti-)progestagens. Abstract to be used at: Congress Mechanism of Action of retinoids, vitamin D and
steroid hormones. Whistler, Canada, January 1995.
Schoonen, W.G.E.J., de Ries, R.H.J., Mommers, G.J.W., de Gooyer, M.E., Struik E., Dijkema R. (1995): The
human glucocorticoid receptor: comparison of binding and transcription modulation with CHO hGR-
MMTV-LUC cells versus binding with IM-9 cells.Keystone Symposium '96 Steroid receptors (poster),
California, USA.
1994
Dijkema R., Teuwen R. , Swinkels J.C. and Schoonen W.G.E.J. (1994): The human progesterone B receptor:
Inhibition of transcription activation by antagonists in CHO cells stably transfected with receptor and
reporter. [Keystone Symp, Steroid/thyroid/retinoic acid super gene family, Taos, New Mexico, February 7-
13, 1994]. J. Cell. Biochem. Suppl 18B, 342, Abstract K 111 (poster).
Orlemans E.O.M., Deckers, G.H., Schoonen, W.G.E.J., Kloosterboer H.J. (1994): Pharmacology of the very
selective antiprogestin Org 31710 and comparison with the antiprogestins RU38486 and ZK98299. Poster
IX International Congress on Hormonal Steroids, Sept. 24-29, Dallas, USA (poster).
Schoonen, W.G.E.J., Joosten, J.W.H. and Kloosterboer, H.J. (1994): Effects of progestagens on cell growth of
human breast tumor cells. Keystone Symposium, Steroid/thyroid/ retinoic acid super gene family, Taos,
New Mexico, February 7-13, 1994. J. Cell. Biochem. Suppl. 18B, 372, Abstract K 347 (poster).
1993
Schoonen W.G.E.J., Joosten J.W.H. and Kloosterboer H.J. (1993): Effects of progestagens on cell growth of
human breast tumor cells. Poster presentatie 11th International Symposium of Steroid Boichemistry and
Molecular Biology, Seefeld, Austria, May 30 - June 2, 1993.
1992
Slootweg M.C., Ederveen A.G.H., Schot L.P.C., Schoonen W.G.E.J. and Kloosterboer H.J. (1992): Estrogen
and progestagen synergistically stimulate osteoblast proliferation. (Abstract, XI th ICCRH, Florence).
Kloosterboer H.J., Schoonen W.G.E.J. and Deckers G.H. (1992): Effects of synthetic steroids in in vitro and in
vivo tumor models. Meeting of Internat. Study Group of Steroid Hormones, Vienna, Austria.

4. 1989
Schoonen, W.G.E.J., Wanamarta, A.H., and Joenje, H. (1989). Inactivation of specific mitochondrial enzymes
by hyperoxia in Chinese hamster ovary cells. Symposium on: Free radicals and cancer, 8-9 December 1989
(poster), Tübingen, Germany.
Wanamarta, A.H., Schoonen, W.G.E.J., and Joenje, H. (1989). Inactivation of specific mitochondrial enzymes
by hyperoxia in HeLa cells. Symposium on: Free radicals and cancer, 8-9 December 1989 (poster),
Tübingen, Germany.
1988
Schoonen, W.G.E.J., Wanamarta, A.H., and Joenje, H. (1988). Effect of hyperoxia on respiratory activity of
CHO cells. Symposium on: Free radicals and cancer, November 1988 (poster), Vienna, Austria.
1986
Schoonen, W.G.E.J., Penders, M.T., van Dam, G.H. and Lambert, J.G.D. (1986). 5ß-Pregnane-3,6,17,20ß-
tetrol and 5ß-pregnane-3,6,17-triol-20-one: steroids of ovarian origin in the African catfish, Clarias
gariepinus, during oocyte maturation. Symposium of Comparative Endocrinology (poster). Belgrad,
Yugoslavia.
1985
Schoonen, W.G.E.J. and Lambert, J.G.D. (1985). Steroidogenesis in the testes and seminal vesicles of Clarias
gariepinus in spawning and non-spawning animals under natural conditions and in non-spawning animals
kept in ponds. Symposium on Fish Culture by the European Society for Comparative Physiology and
Biochemistry (poster). 26-28 August, Barcelona, Spain.
1981
Schoonen, W.G.E.J., Oudejans, R.C.H.M., and Voogt, P.A. (1981). Production of NADPH and acetyl CoA for
lipid biosynthesis in the pyloric caeca of the sea star, Asterias rubens. (poster) Newcastle upon Tyne,
United Kingdom.