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レミケードの時代に栄養療法は必要か?
レミケードを使っているのにこれらは必要なの?
とある有名な先生は




     レミケードの時代に栄養
     療法は必要ありません。
     私は患者さんに栄養療
     法をお勧めしません。
ところが九州地方の有名な先生方は



         栄養療法は重要
         です。レミケードを
         使っているとはいえ、
         できるだけ続けて
         いきましょう。
レミケードを維持投与されている
    患者さんにとって


1. 栄養療法は必要なのか?
2. レミケードと併用するなら
 いつから併用すべき?
レミケードを開始しても栄養療法は続けるべき?

・ 食事を普通に食べられる方もいらっしゃる。
・ 文献的にはレミケードを栄養療法も併用した方が
 治療成績が良いという報告が多い。
・ 当院での方針;
  レミケード開始後半年~1年は栄養療法を継続。
  (特にエレンタール)
  その後再発がなければ、徐々に食事を開始する。
千葉大学からの報告

・ レミケードを受けている74人の患者さんを対象として、
クローン病が再燃する要因を調査。
・ レミケードを使用しても再燃する患者さんは40%。
・ 1日600kcal以上の栄養療法を行っている患者さんは
栄養療法を行っていない患者さんと比較すると再燃が
半分以下であった。
・ 栄養剤はエレンタールでもエンシュア・ラコールでも
効果に変わりなし。
いつから栄養療法を併用すべき?

・ レミケード開始当初から栄養療法を併用する?
それとも再燃してから栄養療法を併用する?
・ レミケードの維持投与を行っても、30%程度の患者さん
が再燃する。
・ 一度再燃すると、なかなか寛解に戻らない。
             ↓
       再燃させないことが大事!
レミケードを使っていても
再燃してしまった場合はどうする?

1.レミケード増量(クローン病のみ)
2.免疫調節剤(アザチオプリンなど)の併用
3.レミケードの再寛解導入療法
4.ヒュミラへの変更
5.ステロイドや血球除去療法の併用
6.栄養療法の強化、徹底
まとめ

・ レミケード時代になっても栄養療法は必要.
(かもしれない)
・ レミケード開始当初から栄養療法は併用すべき.
・ ただし以前ほどの厳密な栄養療法は必要ない.
(かもしれない)
201302患者会
201302患者会
201302患者会

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201302患者会