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Case #1



78 y.o. female brought in by EMS for
weakness and altered mental status
Case #2


28 y.o. male picked up by law enforcement
after being found walking along the highway
at 2 in the morning
Case #3


16 y.o. male brought in with altered mental
status the morning after partying all night
with friends
Case #4


54 y.o. male with witnessed cardiac arrest,
brought in by EMS now with pulses after
AED used
Cases
78 y.o. female brought in by EMS for weakness
and altered mental status

28 y.o. male picked up by law enforcement after
being found walking along the highway at 2 in the
morning

16 y.o. male brought in with altered mental status
the morning after partying all night with friends

54 y.o. male with witnessed cardiac arrest, brought
in by EMS now with pulses after AED used
Case #1


78 y.o. female brought in by EMS for
weakness and altered mental status
Case #1


78 y.o. female brought in by EMS for
weakness and altered mental status

Found to have urosepsis, with a temperature
of 34.8o C
Case #2


28 y.o. male picked up
by law enforcement
after being found
walking along the
highway at 2 in the
morning
Case #2


28 y.o. male picked up
by law enforcement
after being found
walking along the
highway at 2 in the
morning
Case #3


16 y.o. male brought in with altered mental
status the morning after partying all night
with friends
Case #3


16 y.o. male brought in with altered mental
status the morning after partying all night
with friends

Blood sugar of 25 when found, with body
temperature of 36o C
Case #4


54 y.o. male with
witnessed cardiac
arrest, brought in by
EMS now with pulses
after AED used
Case #4


54 y.o. male with
witnessed cardiac
arrest, brought in by
EMS now with pulses
after AED used
Falling Temperatures



       Veronica Bonales, M.D.
   CEPAmerica, Emergency Medicine
Hypothermia
Hypothermia

States with highest death rates

  Alaska

  New Mexico

  North Dakota

  Montana
Hypothermia
Case distribution - Greatest number

  Urban areas

     Environmental exposure

       EtOH

       Illicit Drug Use

       Mental illness

       All exacerbated by homelessness
Physiology
Thermoregulation
Regulatory center
   Temp between
  36.5 - 37.5C
 Peripheral
thermoreceptors
 Central
thermoreceptors
Thermoregulation
Regulatory center
   Temp between
  36.5 - 37.5C
 Peripheral
thermoreceptors
 Central
thermoreceptors
Thermoregulation

 Body temperature can be increased or
decreased in two ways:
   Regulation of heat production
  (thermogenesis)
   Regulation of heat loss (thermolysis)
Regulating Heat Production
   Muscular                    Fats
                               Proteins
     Baseline muscular
    activity                 Glycogen Stores
     Exertion               Endocrine
     Shivering                Role of hormones
                             in setting basal
   Metabolic                 metabolic rate -
     Processing of food      thyroxine and epi
    and nutrients
      Carbohydrates –
      sugars and starches
Regulating Heat Loss
 Heat is lost from the body to the external
environment through the skin, lungs, and
excretions
   The skin is most important in regulating
  heat loss
   Radiation, conduction, convection, and
  evaporation are the major sources of heat
  loss
Heat Loss Mechanisms
Maintenance of
     Thermoregulation
Hypothermic compensation
 Decreased heat loss
   Peripheral vasoconstriction
   Reduction of surface area by body position (or clothing)
   Piloerection (not effective in humans)
 Increased heat production
   Shivering (last resort to maintain temperature)
   Increased voluntary activity
   Increased hormone secretion
   Increased appetite
External Environmental
       Factors
  External environmental factors that may
 contribute to a medical emergency
    Climate
    Season
    Weather
    Atmospheric pressure
    Terrain
Predisposing Factors
Patient’s age
Predisposing medical conditions
 Use of prescription and over-the-counter
medications
Use of alcohol or recreational drugs
Previous rate of exertion
“Indoor” Hypothermia

Occurs with significant medical comorbidities

  Alcoholism

  Sepsis

  Hypothyroid/hypopituitary

Worse outcome than exposure
Hypothermia
Hypothermia
 Hypothermia (CBT less than 95º F [35º
C]) may result from:
  A decrease in heat production
  An increase in heat loss
  A combination of these factors
Hypothermia
 Progression of clinical signs and symptoms
may be divided into three classes
    Mild (core temperature between 93.2º
   and 96.8º F [34º and 36º C])
    Moderate (core temperature between 86º
   and 93º F [30º and 34º C])
    Severe (core temperature below 86
   degrees F [30º C])
Hypothermia

Heart and brain most affected

  Bradycardia, arrhythmias as get colder

  CNS depression, abnormal EEG at temps
  <30 degrees C, EEG shows signal similar to
  brain death 19 - 20 degrees C
Frostbite
Frostbite
 A localized injury that results from
environmentally induced freezing of body
tissues
Pathophysiology
Predisposing factors
Frostbite Classifications/Symptoms
  A common classification separates cold
 injury into three categories
     Frostnip (the mildest form of cold
    exposure) may be treated without loss of
    tissue
    In superficial frostbite, there is at least
   some minimal tissue loss
    With deep frostbite, there is significant
   tissue loss even with appropriate therapy
Superficial Frostbite
Some freezing of epidermal tissue
Initial redness followed by blanching
Diminished sensation
Deep Frostbite
Freezing of epidermal and subcutaneous layers
White appearance
Hard (frozen) to palpation
Loss of sensation
Frostbite
 Edema and blister formation 24 hours after
frostbite injury in area covered by tightly
fitted boot
Frostbite
 Gangrenous necrosis 6 weeks after frostbite
injury
Frostbite
Remove wet clothing

Do not rub extremities

Wrap in blanket

Rapid re-warming in tub of
water (40o C) or warm, wet
packs

Thaw 20 - 40 minutes - distal
tip flushes

Auto-amputation (1 - 2 months)
Submersion
Submersion

Hypothermic considerations
  Common concomitant syndrome
  May be organ protective in cold-water
 submersion
  Always treat hypoxia first
  Treat all submersion patients for
 hypothermia
Factors That Affect Clinical
           Outcome

 Factors that can affect clinical outcome
after a submersion incident
   Temperature of the water
   Length of submersion
   Cleanliness of the water
   Age of the victim
Submersion Incident
   Management
ABCs
Trauma considerations
  Immersion episode of unknown etiology warrants
  trauma management
Post-resuscitation complications
  Adult respiratory distress syndrome (ARDS) or
  renal failure often occur post-resuscitation
  Symptoms may not appear for 24 hours or more
  post-resuscitation
 All submersion patients should be transported
for evaluation
The stickmen face a horrible choice



Questions...?
Cases
Case #1


78 y.o. female brought in by EMS for
weakness and altered mental status

Found to have urosepsis, with a temperature
of 34.8o C
Case #1


Usually elderly with low reserves

Vasodilation secondary to infection

Poorly functioning CNS and endocrine system

Independent predictor of mortality
Case #2


28 y.o. male picked up
by law enforcement
after being found
walking along the
highway at 2 in the
morning
Case #2
Treat frostbite

... But, severe
hypothermia....

  Bair hugger

  IV, peritoneal,
  bladder, chest
  rewarming

     Cordis, DPL, foley,
     chest tubes
Case #3

16 y.o. male brought in with altered mental
status the morning after partying all night
with friends

Blood sugar of 25 when found, with body
temperature of 35o C, (spent night outdoors
in barn)
Case #3

Pediatric livers have low glycogen stores

  Alcohol causes starvation state

     Glycemic stores used

     No gluconeogenesis

        Leads to clinical triad of: coma,
        hypoglycemia, hypothermia
Case #4


54 y.o. male with
witnessed cardiac
arrest, brought in by
EMS now with pulses
after AED used
Case #4
Therapeutic
hypothermia

  Should start with
  EMS

  Keep on for 24
  hours

  Improved neuro
  status on discharge
Things to Remember

Can have “indoor” hypothermia

Triad of coma, hypoglycemia and
hypothermia

Rapid rewarming of extremities with no
rubbing
Thank you!

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Hypothermia FCA 1211

  • 1. A Buffalo Squirrels Production
  • 2. Case #1 78 y.o. female brought in by EMS for weakness and altered mental status
  • 3. Case #2 28 y.o. male picked up by law enforcement after being found walking along the highway at 2 in the morning
  • 4. Case #3 16 y.o. male brought in with altered mental status the morning after partying all night with friends
  • 5. Case #4 54 y.o. male with witnessed cardiac arrest, brought in by EMS now with pulses after AED used
  • 6. Cases 78 y.o. female brought in by EMS for weakness and altered mental status 28 y.o. male picked up by law enforcement after being found walking along the highway at 2 in the morning 16 y.o. male brought in with altered mental status the morning after partying all night with friends 54 y.o. male with witnessed cardiac arrest, brought in by EMS now with pulses after AED used
  • 7. Case #1 78 y.o. female brought in by EMS for weakness and altered mental status
  • 8. Case #1 78 y.o. female brought in by EMS for weakness and altered mental status Found to have urosepsis, with a temperature of 34.8o C
  • 9. Case #2 28 y.o. male picked up by law enforcement after being found walking along the highway at 2 in the morning
  • 10. Case #2 28 y.o. male picked up by law enforcement after being found walking along the highway at 2 in the morning
  • 11. Case #3 16 y.o. male brought in with altered mental status the morning after partying all night with friends
  • 12. Case #3 16 y.o. male brought in with altered mental status the morning after partying all night with friends Blood sugar of 25 when found, with body temperature of 36o C
  • 13. Case #4 54 y.o. male with witnessed cardiac arrest, brought in by EMS now with pulses after AED used
  • 14. Case #4 54 y.o. male with witnessed cardiac arrest, brought in by EMS now with pulses after AED used
  • 15. Falling Temperatures Veronica Bonales, M.D. CEPAmerica, Emergency Medicine
  • 17. Hypothermia States with highest death rates Alaska New Mexico North Dakota Montana
  • 18. Hypothermia Case distribution - Greatest number Urban areas Environmental exposure EtOH Illicit Drug Use Mental illness All exacerbated by homelessness
  • 20. Thermoregulation Regulatory center Temp between 36.5 - 37.5C Peripheral thermoreceptors Central thermoreceptors
  • 21. Thermoregulation Regulatory center Temp between 36.5 - 37.5C Peripheral thermoreceptors Central thermoreceptors
  • 22. Thermoregulation Body temperature can be increased or decreased in two ways: Regulation of heat production (thermogenesis) Regulation of heat loss (thermolysis)
  • 23. Regulating Heat Production Muscular Fats Proteins Baseline muscular activity Glycogen Stores Exertion Endocrine Shivering Role of hormones in setting basal Metabolic metabolic rate - Processing of food thyroxine and epi and nutrients Carbohydrates – sugars and starches
  • 24. Regulating Heat Loss Heat is lost from the body to the external environment through the skin, lungs, and excretions The skin is most important in regulating heat loss Radiation, conduction, convection, and evaporation are the major sources of heat loss
  • 26. Maintenance of Thermoregulation Hypothermic compensation Decreased heat loss Peripheral vasoconstriction Reduction of surface area by body position (or clothing) Piloerection (not effective in humans) Increased heat production Shivering (last resort to maintain temperature) Increased voluntary activity Increased hormone secretion Increased appetite
  • 27. External Environmental Factors External environmental factors that may contribute to a medical emergency Climate Season Weather Atmospheric pressure Terrain
  • 28. Predisposing Factors Patient’s age Predisposing medical conditions Use of prescription and over-the-counter medications Use of alcohol or recreational drugs Previous rate of exertion
  • 29. “Indoor” Hypothermia Occurs with significant medical comorbidities Alcoholism Sepsis Hypothyroid/hypopituitary Worse outcome than exposure
  • 31. Hypothermia Hypothermia (CBT less than 95º F [35º C]) may result from: A decrease in heat production An increase in heat loss A combination of these factors
  • 32. Hypothermia Progression of clinical signs and symptoms may be divided into three classes Mild (core temperature between 93.2º and 96.8º F [34º and 36º C]) Moderate (core temperature between 86º and 93º F [30º and 34º C]) Severe (core temperature below 86 degrees F [30º C])
  • 33. Hypothermia Heart and brain most affected Bradycardia, arrhythmias as get colder CNS depression, abnormal EEG at temps <30 degrees C, EEG shows signal similar to brain death 19 - 20 degrees C
  • 35. Frostbite A localized injury that results from environmentally induced freezing of body tissues Pathophysiology Predisposing factors
  • 36. Frostbite Classifications/Symptoms A common classification separates cold injury into three categories Frostnip (the mildest form of cold exposure) may be treated without loss of tissue In superficial frostbite, there is at least some minimal tissue loss With deep frostbite, there is significant tissue loss even with appropriate therapy
  • 37. Superficial Frostbite Some freezing of epidermal tissue Initial redness followed by blanching Diminished sensation
  • 38. Deep Frostbite Freezing of epidermal and subcutaneous layers White appearance Hard (frozen) to palpation Loss of sensation
  • 39. Frostbite Edema and blister formation 24 hours after frostbite injury in area covered by tightly fitted boot
  • 40. Frostbite Gangrenous necrosis 6 weeks after frostbite injury
  • 41. Frostbite Remove wet clothing Do not rub extremities Wrap in blanket Rapid re-warming in tub of water (40o C) or warm, wet packs Thaw 20 - 40 minutes - distal tip flushes Auto-amputation (1 - 2 months)
  • 43. Submersion Hypothermic considerations Common concomitant syndrome May be organ protective in cold-water submersion Always treat hypoxia first Treat all submersion patients for hypothermia
  • 44. Factors That Affect Clinical Outcome Factors that can affect clinical outcome after a submersion incident Temperature of the water Length of submersion Cleanliness of the water Age of the victim
  • 45. Submersion Incident Management ABCs Trauma considerations Immersion episode of unknown etiology warrants trauma management Post-resuscitation complications Adult respiratory distress syndrome (ARDS) or renal failure often occur post-resuscitation Symptoms may not appear for 24 hours or more post-resuscitation All submersion patients should be transported for evaluation
  • 46. The stickmen face a horrible choice Questions...?
  • 47. Cases
  • 48. Case #1 78 y.o. female brought in by EMS for weakness and altered mental status Found to have urosepsis, with a temperature of 34.8o C
  • 49. Case #1 Usually elderly with low reserves Vasodilation secondary to infection Poorly functioning CNS and endocrine system Independent predictor of mortality
  • 50. Case #2 28 y.o. male picked up by law enforcement after being found walking along the highway at 2 in the morning
  • 51. Case #2 Treat frostbite ... But, severe hypothermia.... Bair hugger IV, peritoneal, bladder, chest rewarming Cordis, DPL, foley, chest tubes
  • 52. Case #3 16 y.o. male brought in with altered mental status the morning after partying all night with friends Blood sugar of 25 when found, with body temperature of 35o C, (spent night outdoors in barn)
  • 53. Case #3 Pediatric livers have low glycogen stores Alcohol causes starvation state Glycemic stores used No gluconeogenesis Leads to clinical triad of: coma, hypoglycemia, hypothermia
  • 54. Case #4 54 y.o. male with witnessed cardiac arrest, brought in by EMS now with pulses after AED used
  • 55. Case #4 Therapeutic hypothermia Should start with EMS Keep on for 24 hours Improved neuro status on discharge
  • 56. Things to Remember Can have “indoor” hypothermia Triad of coma, hypoglycemia and hypothermia Rapid rewarming of extremities with no rubbing
  • 57. Thank you! Slides can be reviewed: www.slideshare.net/docmontey

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