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GGIAR Generation Challenge Programme
(GCP)

Partnerships in modern crop breeding
for food security

November 2011
GCP in brief




Launched in August 2003
10-year framework (2004–2008; 2009–2013)
About US$15M annual budget





Target areas: Harsh drought-prone environments




Africa (SSA), S & SE Asia, LA

Mandate crops






Via CGIAR (DFID, EC, SDC, USAID, CG Fund Council)
Bill & Melinda Gates Foundation

Cereals: maize, rice, sorghum, wheat,
Legumes: beans, chickpeas, cowpeas, groundnuts
Root and tubers: cassava

A CGIAR Challenge Programme hosted at CIMMYT

Main objective: To use genetic diversity and advanced plant science to
improve crops for greater food security in the developing world
GCP : A broker in plant science bridging the gap between upstream
and applied science
www.generationcp.org
Partnerships
GCP network
The GCP network in 2010:
200+ Institutes
Germplasm
Breeding
Private
sector

Technology

CGIAR

Private
sector

Products/Impact
Farmer’s field

ARIs

Country
programmes
NGOs

Germplasm
Environments

Needs
Major achievement: GCP community
Partnerships


EPMR panel noted that GCP community is one of the
Programme’s crucial assets. In their words: “Perhaps the
most important value of GCP thus far, is the opportunities
it has provided for people of diverse backgrounds to think
collectively about solutions to complex problems, and, in
the process, to learn from one another.”

Linking upstream with applied science


The sorghum case: From Cornell to Moi University with a
stop in Brazil



Within a decade: Plantlet under hydroponics – Gene
cloned – Favourable alleles identified – Improved
germplasm for Brazil – Improved germplasm for Kenya

Evolution of roles and responsibilities


Leader become mentors



Trainees become doers and leaders
Research Themes and Logframe
Research Organisation (Management)
3. Crop information systems

Databases, Information Network
1. Integrated crop breeding
Phenotyping

Germplasm

Phenotyping

Genes

Molecular breeding

2. Comparative and applied genomics

Human resources & infrastructure
4. Capacity building

Breeding programmes
Improved genotypes

Delivery Plans
Products

5. Product delivery

Improved germplasm in farmers’ fields
The two phases of the Programme
Phase I (2004–2008):
A combination of commissioned and competitive projects
‘Opportunistic’ and high project turn over
Establishing the GCP community

Identifying the winners and opportunities for Phase II

Phase II (2009–2013):
Mid-term activities

Focused and targeted research
Major effort in service development
Clear impact indicators by 2013 to evaluate success

A needs and bottom-up approach: Research and services

2014: Transition year
Selected major outputs
Access to genetic resources
 Genotyping for 21 reference sets of CGIAR mandate crops
 Substitution lines (groundnuts, rice)
 Mutant collections (rice, potatoes, beans)

 Synthetics (groundnuts and wheat)
 MAGIC (cowpeas, rice, sorghum) NAM (rice) BCNAM, (sorghum)

Development of genomic resources
 BAC libraries and EST sequences (legumes, cassava)
 New markers: DArTs, SSRs and SNPs (all crops)

Identification of markers for biotic stresses
 Validated markers for resistance to pests and diseases for beans,
cassava, chickpeas, cowpeas, groundnuts, maize, potatoes and rice
Selected major outputs
Identification of markers for abiotic stresses
 Tolerance to Al toxicity in sorghum and salinity and phosphorus
deficiency in rice
 Drought tolerance in chickpeas, cowpeas, maize, rice, wheat

New tools
 GIS, bioinformatic and data management tools
 Marker tool kit

Enhanced capacities in country programmes
 Human capacities / Local infrastructure / Analytical power

Socioeconomic studies
 Ex ante analyses MB impact in developing countries
 Impact briefs
The 7 Research Initiatives:

50% of GCP resources to RIs in Phase II


Basis: RIs are crop-, crop cluster-, and area-based



Key trait: Main focus of all the RIs is drought tolerance



Target crops/area and target countries/countries of planned research
1.

Cassava: Nigeria, Ghana, Tanzania, Uganda/Brazil, Colombia

2.

Legumes



Cowpeas: Burkina Faso, Mozambique, Senegal/USA



4.

Chickpeas: Ethiopia, India, Kenya



3.

Beans: Ethiopia, Kenya, Malawi, Mexico, Nicaragua, Zimbabwe

Groundnuts: Malawi, Senegal, Tanzania

Maize: China, India, Indonesia, Kenya, Thailand, The Philippines, Vietnam
Rice: Africa – Burkina Faso, Mali, Nigeria; Asia – Bangladesh, Cambodia,
Thailand, Vietnam, Myanmar

5.

Sorghum: Mali (additional countries via CoP to be established)/Australia

6.

Wheat: Africa – Ethiopia, Morocco; Asia – China, India/Australia

7.

Comparative genomics to improve cereal yields in high-aluminium and lowphosphorus soils (maize, rice, sorghum): Indonesia, Kenya, Niger/Brazil
An Integrated Breeding Platform
to support reeding in the South
www.integratedbreeding.net
Overall objective
To provide access to modern breeding
technologies, breeding material and related
information in a centralised and functional manner
to improve plant breeding efficiency in developing
countries.


Short-term objective
To establish a minimum set of tools, data
management infrastructure and services to
demonstrate that molecular breeding can be
efficiently applied to eight crops spread across 14
user cases


Multilateral funding for an overall budget
of US$ 20M over 5 years

Mainly Gates, DFID, EC
The IB Platform will offer:
Access to Breeding Services:
•
•
•

well characterised and useful genetic resources
quality, economic high throughput genotyping
sophisticated phenotype and metabolite analyses

Access to Informatics Tools:
•
•
•

for breeding logistics and data management
analysis and decision support for molecular breeding
accumulated public crop information of certified quality

Capacity Development - Training and support for:
•
•

•
•
•
•

planning and comparing breeding strategies
data management and curation and quality control
analysis and decision support
use of markers and molecular breeding techniques
phenotyping sites and protocols
use and protection of intellectual property

Community development
•
•

support for communities of practice by crop or discipline
facilitation of germplasm exchange

The IBP will not do breeding per se
Services

Integrated Breeding Platform

Breeding
Services

Support
Services

Portal

Information System

Configurable Breeding Workflow System

Cyber Infrastructure

Custom
Formatted
Data
Files

Web Service
Data Source

Local
Database

Data Sources

SoapLab

High
Performance
Computer

MOBY, GDPC,
BioCase/TAPIR
The IBP Configurable Breeding Workflow System

Breeding Activities
Project
Planning

Germplasm
Management

Germplasm
Evaluation

Molecular
Analysis

Data
Analysis

Open Project
Specify objectives
Identify team
Data
AA resources
Define strategy

Parental selection
Crossing
Population
development

Experimental Design
Fieldbook production
Data collection
Data loading

Marker selection
Fingerprinting
Genotyping
Data loading

Quality Assurance
Trait analysis
Genetic Analysis
QTL Analysis
Index Analysis

Workbench
administration
&
configuration
Administration
Project conf.

Breeding
Management
System
Breeding mana.
Genealogy mana.
Query tools

Field Trial
Management
System
Trial Fieldbook
Environment
characterization
system

Breeding Applications

Genotypic
Data
Management
System
Sample mana.
Sample
management

Analytical
Tools
Data management
Statistical analysis
Molecular Genetic

Breeding
Decisions
Selected lines
Recombines
Recombination
plans

Decision
Support Tools
Sel. Indices
Breeding App.
MARS App.
Cross Prediction
Simulation

Analytical Pipeline
Conclusion and Perspectives
Major Challenges Today
 M&E: Implement realistic workplans
 Clear milestones, products and timelines
 Reliable Delivery Plans with clear impact indicators

 Ensure delivery and sustainable use of GCP products
 Product delivery strategy
 Reinforce ownership by the GCP community

 Partnership
 Balance community momentum and a focused research agenda

 Data release and quality control
 Difficult to finish the work (time, resources)
 Still not a lot of data in our Central Registry today
 Quality and documentation are very variable

Change in mindset: from institutional to corporate
Conclusions


A vibrant community bridging the gap between basic and
applied agricultural science providing new tools for plant
breeding






Agile programme structure
Dynamic network of partners
Significant amount of products already been generated
Already an impact in the breeding community

The success of the GCP will be judged on the
quality of the science and relevance of its
products for impact on crop improvement

Visit us: www.generationcp.org
GCP people:

The Programme’s greatest asset!

Participants of the GCP General Research Meeting, September 2011

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2011: Introduction to the CGIAR Generation Challenge Programme (GCP)

  • 1. GGIAR Generation Challenge Programme (GCP) Partnerships in modern crop breeding for food security November 2011
  • 2. GCP in brief    Launched in August 2003 10-year framework (2004–2008; 2009–2013) About US$15M annual budget    Target areas: Harsh drought-prone environments   Africa (SSA), S & SE Asia, LA Mandate crops     Via CGIAR (DFID, EC, SDC, USAID, CG Fund Council) Bill & Melinda Gates Foundation Cereals: maize, rice, sorghum, wheat, Legumes: beans, chickpeas, cowpeas, groundnuts Root and tubers: cassava A CGIAR Challenge Programme hosted at CIMMYT Main objective: To use genetic diversity and advanced plant science to improve crops for greater food security in the developing world GCP : A broker in plant science bridging the gap between upstream and applied science www.generationcp.org
  • 5. The GCP network in 2010: 200+ Institutes Germplasm Breeding Private sector Technology CGIAR Private sector Products/Impact Farmer’s field ARIs Country programmes NGOs Germplasm Environments Needs
  • 6. Major achievement: GCP community Partnerships  EPMR panel noted that GCP community is one of the Programme’s crucial assets. In their words: “Perhaps the most important value of GCP thus far, is the opportunities it has provided for people of diverse backgrounds to think collectively about solutions to complex problems, and, in the process, to learn from one another.” Linking upstream with applied science  The sorghum case: From Cornell to Moi University with a stop in Brazil  Within a decade: Plantlet under hydroponics – Gene cloned – Favourable alleles identified – Improved germplasm for Brazil – Improved germplasm for Kenya Evolution of roles and responsibilities  Leader become mentors  Trainees become doers and leaders
  • 8. Research Organisation (Management) 3. Crop information systems Databases, Information Network 1. Integrated crop breeding Phenotyping Germplasm Phenotyping Genes Molecular breeding 2. Comparative and applied genomics Human resources & infrastructure 4. Capacity building Breeding programmes Improved genotypes Delivery Plans Products 5. Product delivery Improved germplasm in farmers’ fields
  • 9. The two phases of the Programme Phase I (2004–2008): A combination of commissioned and competitive projects ‘Opportunistic’ and high project turn over Establishing the GCP community Identifying the winners and opportunities for Phase II Phase II (2009–2013): Mid-term activities Focused and targeted research Major effort in service development Clear impact indicators by 2013 to evaluate success A needs and bottom-up approach: Research and services 2014: Transition year
  • 10. Selected major outputs Access to genetic resources  Genotyping for 21 reference sets of CGIAR mandate crops  Substitution lines (groundnuts, rice)  Mutant collections (rice, potatoes, beans)  Synthetics (groundnuts and wheat)  MAGIC (cowpeas, rice, sorghum) NAM (rice) BCNAM, (sorghum) Development of genomic resources  BAC libraries and EST sequences (legumes, cassava)  New markers: DArTs, SSRs and SNPs (all crops) Identification of markers for biotic stresses  Validated markers for resistance to pests and diseases for beans, cassava, chickpeas, cowpeas, groundnuts, maize, potatoes and rice
  • 11. Selected major outputs Identification of markers for abiotic stresses  Tolerance to Al toxicity in sorghum and salinity and phosphorus deficiency in rice  Drought tolerance in chickpeas, cowpeas, maize, rice, wheat New tools  GIS, bioinformatic and data management tools  Marker tool kit Enhanced capacities in country programmes  Human capacities / Local infrastructure / Analytical power Socioeconomic studies  Ex ante analyses MB impact in developing countries  Impact briefs
  • 12.
  • 13. The 7 Research Initiatives: 50% of GCP resources to RIs in Phase II  Basis: RIs are crop-, crop cluster-, and area-based  Key trait: Main focus of all the RIs is drought tolerance  Target crops/area and target countries/countries of planned research 1. Cassava: Nigeria, Ghana, Tanzania, Uganda/Brazil, Colombia 2. Legumes   Cowpeas: Burkina Faso, Mozambique, Senegal/USA  4. Chickpeas: Ethiopia, India, Kenya  3. Beans: Ethiopia, Kenya, Malawi, Mexico, Nicaragua, Zimbabwe Groundnuts: Malawi, Senegal, Tanzania Maize: China, India, Indonesia, Kenya, Thailand, The Philippines, Vietnam Rice: Africa – Burkina Faso, Mali, Nigeria; Asia – Bangladesh, Cambodia, Thailand, Vietnam, Myanmar 5. Sorghum: Mali (additional countries via CoP to be established)/Australia 6. Wheat: Africa – Ethiopia, Morocco; Asia – China, India/Australia 7. Comparative genomics to improve cereal yields in high-aluminium and lowphosphorus soils (maize, rice, sorghum): Indonesia, Kenya, Niger/Brazil
  • 14. An Integrated Breeding Platform to support reeding in the South www.integratedbreeding.net Overall objective To provide access to modern breeding technologies, breeding material and related information in a centralised and functional manner to improve plant breeding efficiency in developing countries.  Short-term objective To establish a minimum set of tools, data management infrastructure and services to demonstrate that molecular breeding can be efficiently applied to eight crops spread across 14 user cases  Multilateral funding for an overall budget of US$ 20M over 5 years Mainly Gates, DFID, EC
  • 15. The IB Platform will offer: Access to Breeding Services: • • • well characterised and useful genetic resources quality, economic high throughput genotyping sophisticated phenotype and metabolite analyses Access to Informatics Tools: • • • for breeding logistics and data management analysis and decision support for molecular breeding accumulated public crop information of certified quality Capacity Development - Training and support for: • • • • • • planning and comparing breeding strategies data management and curation and quality control analysis and decision support use of markers and molecular breeding techniques phenotyping sites and protocols use and protection of intellectual property Community development • • support for communities of practice by crop or discipline facilitation of germplasm exchange The IBP will not do breeding per se
  • 16. Services Integrated Breeding Platform Breeding Services Support Services Portal Information System Configurable Breeding Workflow System Cyber Infrastructure Custom Formatted Data Files Web Service Data Source Local Database Data Sources SoapLab High Performance Computer MOBY, GDPC, BioCase/TAPIR
  • 17. The IBP Configurable Breeding Workflow System Breeding Activities Project Planning Germplasm Management Germplasm Evaluation Molecular Analysis Data Analysis Open Project Specify objectives Identify team Data AA resources Define strategy Parental selection Crossing Population development Experimental Design Fieldbook production Data collection Data loading Marker selection Fingerprinting Genotyping Data loading Quality Assurance Trait analysis Genetic Analysis QTL Analysis Index Analysis Workbench administration & configuration Administration Project conf. Breeding Management System Breeding mana. Genealogy mana. Query tools Field Trial Management System Trial Fieldbook Environment characterization system Breeding Applications Genotypic Data Management System Sample mana. Sample management Analytical Tools Data management Statistical analysis Molecular Genetic Breeding Decisions Selected lines Recombines Recombination plans Decision Support Tools Sel. Indices Breeding App. MARS App. Cross Prediction Simulation Analytical Pipeline
  • 19. Major Challenges Today  M&E: Implement realistic workplans  Clear milestones, products and timelines  Reliable Delivery Plans with clear impact indicators  Ensure delivery and sustainable use of GCP products  Product delivery strategy  Reinforce ownership by the GCP community  Partnership  Balance community momentum and a focused research agenda  Data release and quality control  Difficult to finish the work (time, resources)  Still not a lot of data in our Central Registry today  Quality and documentation are very variable Change in mindset: from institutional to corporate
  • 20. Conclusions  A vibrant community bridging the gap between basic and applied agricultural science providing new tools for plant breeding     Agile programme structure Dynamic network of partners Significant amount of products already been generated Already an impact in the breeding community The success of the GCP will be judged on the quality of the science and relevance of its products for impact on crop improvement Visit us: www.generationcp.org
  • 21. GCP people: The Programme’s greatest asset! Participants of the GCP General Research Meeting, September 2011