The Brigham and Women's Hospital Innovation Hub (iHub) was created to foster innovation among clinicians and staff and help move ideas from concept to implementation. The iHub provides programs like innovation accelerators and advisory services to help innovators overcome common barriers to innovation such as lack of funding, time, and clarity on next steps. Notable innovations supported include reducing MRI analysis time from 3 days to 3 seconds. Innovators report that the iHub helped connect them to resources and partners to further develop their ideas.

1. HxRefactored
Innovating from Within

2. Brigham History of Innovation
2
1954 The first successful
human organ transplant, a
kidney transplanted from one
identical twin to another, is
accomplished. In 1990,
Joseph Murray, MD, receives
the Nobel Prize for this work
and the subsequent
development of
immunosuppressive drugs.

3. 3
Expanding a Tradition of Innovation
Clinical & Scientific
Pioneer
World-renowned faculty
and a long history of
medical firsts.
Born out of the
President’s Fund
Hospital leadership recognized
the need for a program to
break down these barriers.
Untapped
Innovation Potential
A 2013 survey showed critical
barriers, in order of impact:
1. Clarity on Next Steps
2. Funding
3. Time

4. Brigham Innovation Hub
VISION:
Disrupt traditional medicine and reinvent healthcare by
unleashing knowledge and expertise of BWH clinicians and staff.
MISSION:
Foster innovation at BWH at all stages of development and
transform ideas from creation to dissemination.
GOAL:
Support innovators where they are, regardless of experience or
idea stage.
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5. Value Propositions
iHub tackles barriers to innovation at the earliest stages.
We…
1. Fill gaps between research and other technology transfer programs.
2. Develop & provide custom programs that overcome the unique
challenges to innovating and advancing innovation at an AMC.
3. Foster innovation through connecting innovators with the right resources
and collaborators.
4. Navigate internal & external innovators through the innovation process at
BWH & Partners.
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6. Problem = Spark
6

8. What Makes iHub Programs Different
iHubOther Programs
8

9. • Includes Clinical: Expands universe of problems that can be addressed
• Builds Teams:
– Clinical/Scientific
– Engineer
– Human Factor/UX Design
– Industry
– Business/Entrepreneur
• Highly Collaborative: Teams work together in concept formation,
solution exploration, early prototyping. Teams continue as it makes sense.
Innovator Support
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10. Accelerator
Structured innovation
support for individuals,
departments, or
Programs at BWH
Advisory Services
Project mentoring
and industry
connections
Resources
Workshops, online
resources, other
innovation tools and
visiting speakers
External Engagement
Connect external
innovation community
to BWH researchers &
clinicians
Products and Services

11. Departmental Innovation Series
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Pulmonary & Critical Care
April 2014
Surgery
November 2014
Radiology
May 2015
Behavioral Health
November 2015
Trauma
March 2016
Machine Learning
January 2016

12. Innovation Accelerator
Department/
Care Area
Problem Pitch
Problem
Definition
Concept
Generation
Funding
Pitch

14. Translation Accelerator
Lesley Solomon, M.B.A
Executive Director
Brian Mullen, Ph.D.
Manager, Innovation Strategy
Jeff Greenberg, M.D, M.B.A
Medical Director
Beverly Hardy
Manager, Innovation Strategy
iHub Team Approach
Additional
Resources
• New Product Development
• Design Strategy
• Commercialization Strategy
• Research Translation
• Fundraising,
• Relationships,
• Marketing,
• Growth strategy
• Consulting background
• MD perspective
• Hospital administration
perspective
• Product management
• User centric approach
• App/software dev

15. Team Action Matrix
15
Project Lead Brian Mullen
Sprint Goal Draft Pitch Deck
Next team meeting/end of sprint Target 4/22 or 4/29
Atendees: Jeff, Bev, Sid, Brian, Lesley, Troy,
Goal/ Milestone Question/ Hypothesis Action Owner Status Priority
Market 3 slides on market
 Size
 Competition
 Go-to-market
segment/go to market Detailed marketing slides JG/LS 2
(Lesley, resident, HBS, Interns) size JG/LS
prices JG/LS
Sales/BD
ID possible collaborators, co-dev & exit
opportunities Roche Diagnostics
Walgreens/CVS
reach out and judge interest level LS
(Lesley, Jeff & Brian) LS
Troy
Product Development & Opps
Map out product Dev plan
Products draft product roadmap BM LS HS Linked to
(Bev & Brian) Design shop - hardware find dev shop BM HS Bev Market
App Review BH HS Bus. Strat
Business Strategy New Co/License Discuss with Steve and Partners BM LS
(Lesley, Brian, Jeff) Collaboration ID 5-10 BM LS Troy 3
Apply to MC 3/31 Accelerator/grants Work on applications BM LS
Legal/Admin - Partners/Hospital navigation Getting initial feedback Reg Find consultant for advice Troy Linked to
(Sid) Get initial feedback Reimb. Talk with Peter at BCBS Brian marketing
IP, New Co & Partners ID steps &/barriers Sid/Troy & Product
Clinical testing Research project
Summary of what would be needed and plan
of action for research
Sid
(Sid, Jeff, Brian) Draft plan forward Hadi/MGH
Other Find business Partner Bla… fellow HBS BM / LS 1
(Jeff, Brian, Sid) Pitch Deck Contribute content/slides for deck
5-10 ideas Name Brainstorm Team

16. BWH Innovator – Alexander Lin, PhD
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• Origin: Center for Clinical Spectroscopy research
• Innovator: Alexander Lin, PhD
• Idea: Increase use of MR spectroscopy clinically by reducing time for
diagnosis/results from 3 days to 3 seconds
• Collaboration: Dr. Lin worked with a postdoc from his lab, an HBS student, a
Mass Art student and a software engineer
• Innovation Stage: Forming company (BrainSpec) and currently negotiating
to out-license technology from BWH

17. Innovator Feedback
Dr. Sophia Koo: “iHub was helpful in identifying potential commercialization partners
and resources within Partners to help move this concept forward more concretely as
an early-stage company.“
Dr. Alex Lin: “I had been thinking about this for 15 years and was finally able to build
it with iHub.”
Dr. Ritu Gill: “I came for the free lunch and got $20,000.”
Dr. Laura Safar: “The iHub innovation series provided the support that allowed our
team to ‘break the electronic ice’ and translate our collective decades of clinical
experience into a promising app with chances of being successfully implemented.
Dr. Raja Abdulnour: “There is no doubt that without the iHub, I would still be a
dreamer.”

18. Lesley Solomon
Executive Director
David Bates
Chief Innovation Officer
Brian Mullen
Manager,
Innovation Strategy
Jeff Greenberg
Medical Director
BWHiHub.org
@BWHiHub
Innovation Hub Core Team
Beverly Hardy
Manager,
Innovation Strategy