2. The CNS stimulants mostly produced a generalized action
which may
Produce convulsion at higher doses.
3. TYPE OF DRUGS NAME OF DRUGS
ANALEPTICS PICROTOXIN,PENTYLENE
TETRAZOLE,MEDAFINIL,
DOXAZEPAM HYDROCHLORIDE.
METHYLXANTHINES : CAFFINE,THEOPHYLLENE, THE
OBROMINE.
CENTRAL SYMPATHOMIMETIC
AGENTS :
AMPHETAMINE,
METHAMPHETAMINE,
PHENTERMINE,BENZOPHETAMI
NE, FENFLURAMINE
ANTIDEPRESSANTS :
a) MONO AMINE OXIASE INHIBITORS PHENELZINE
SULFATE,TRANYLCYPROMINE
SULFATE
b)TRICYCLIC ANTIDEPRESSANTS IMIPRAMINE,DESIMIPRAMINE,
CLOMIPRAMINE,
AMITRYPTILENE
4.
5. 1.The traditional analeptics are potent and non-selective.
2.They can be illustrated by
a)picrotoxin
& b) PTZ
3.BOTH OF THEM ARE OBSOLATED NOW.
4.But used in research purpose.
5.Newer agents
a)modafinil
& b)doxapram are selective
6.These two are used in narcolepsy and as respiratory
stimulant.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20. References :
1.Wilson & Gisvold’s Organic Medicinal and
Pharmaceutical chemistry
2.Essentials of Medical Pharmacology
-KD TRIPATHY
