3. Announcements
• Next test
• November 23, 2015
• Chapters 12 Cardiovascular and 13 Lymphatic
• Next homework due
• November 23, 2015
• Journal 5 (main campus)
• Homework 5 (satellite campus)
3
5. Chapter 12 | Cardiovascular
• Objectives
• Describe the location, size, position, and anatomy of the heart.
• Explain the physiological functions of the heart; sounds, blood supply, cycle,
and conduction.
• Describe the structure and function of arteries, veins, and capillaries.
• Compare and contrast systemic, pulmonary, and hepatic portal circulation.
• Define blood pressure.
• Describe the factors that influence the fluctuation of blood pressure.
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11. Chapter 12 | Heart
• Heart sounds
• lub
• Atrioventricular (AV) valves closing with
ventricular contraction (systole)
• dup
• Semilunar (SL) valves closing with
ventriclular relaxation (diastole)
• DUP - Diastole
DUP LUB
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12. Chapter 12 | Heart
• Blood flow through heart
• Two separate pumps
• right sided pump
• left sided pump
• superior and inferior vena cava
• → right atrium
• → right AV (tricuspid) valve
• →right ventricle
• → pulmonary SL valve
• → pulmonary artery to lungs
• → pick up O2 drop off CO2
• →4 pulmonary veins
• → left atrium
• → left AV (bicuspid) valve
• → left ventricle
• → aortic SL valve
• → aorta
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13. Chapter 12 | Heart
• Blood flow through heart
• Two separate pumps
• right sided pump
• left sided pump
• Two separate circulations
• pulmonary circulation
• lungs
• systemic circulation
• rest of body
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14. Chapter 12 | Heart
• Blood supply to the heart
• coronary circulation
• blood supply to heart muscle
• myocardium requires constant
supply of blood
• coronary arteries
• right and left
• branch directly off of aorta
• coronary veins
• coronary sinus
• right atrium
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15. Chapter 12 | Heart
• Myocardial infarction (MI) Heart attack
• coronary thrombosis or coronary embolism block
• O2 deprivation results in death of cells
• Angina pectoris
• severe chest pain when O2 is to heart is reduced
• precursor to MI
• Coronary bypass surgery
• harvested veins or arteries reroute
coronary arteries
• Angioplasty
• inserted device expands artery to normalize blood supply
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16. Chapter 12 | Heart
• Cardiac cycle
• cardiac cycle one complete heartbeat
• 0.8 seconds
• systole
• diastole
• 72 beats per minute (bpm) average
• stroke volume
• Volume of blood pumped from both ventricles each heartbeat
• cardiac output
• Volume of blood ejected by one ventricle per minute
• 5 liters average
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17. Chapter 12| cardiovascular practice
• What is the function of the right atria of the heart?
• Receive deoxygenated blood from the body
• What is the function of the right ventricle of the heart?
• Pump deoxygenated blood to the lungs
• What is the function of the left atria of the heart?
• Receive oxygenated blood from the lungs
• What is the function of the left ventricle of the heart?
• Pump oxygenated blood to the body
Answer the following questions
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18. Chapter 12| cardiovascular practice
• What is the name of the inner membrane of the heart?
• endocardium
• What are the names (3) of the outer membrane of the heart?
• Epicardium
• Visceral epicardium
• Parietal epicardium
• What occurs during systole? What occurs during diastole?
• Systole; heart contraction
• Diastole; heart relaxation
Answer the following questions
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19. Chapter 12| cardiovascular practice
• What is the circulation for the heart called?
• Coronary circulation
• What are the other two major circulation circuits of the body?
• Pulmonary circulation
• Systemic circulation
• The volume of blood pumped from both ventricles each heartbeat is:
• Stroke volume
• The volume of blood ejected by one ventricle per minute is the:
• Cardiac output
Answer the following questions
19
20. Chapter 12 | Heart
• Conduction system
• Rhythmic contraction
• Autonomic control of rhythm
• Heart has built-in coordinating system
• Contractions coordinated by electric impulses
• Intercalated discs
• Link cardiac muscle fibers
• Atria linked together
• Ventricles lined together
• Both atria contract in unison
• Both ventricles contract in unison
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25. Chapter 12| cardiovascular practice
• What structure is the natural “pacemaker” of the heart?
• Sinoatrial node
• What heart structures contract in unison?
• Atria contract together
• Ventricles contract together
• What cellular level structure allows the electrical impulse to spread
to cardiac muscle cells?
• Intercalated discs
Answer the following questions
25
26. Chapter 12| cardiovascular practice
• Where does the impulse travel after the SA node and AV node?
• AV bundle of HIS (right and left) →
• Perkinje fibers
• A graphic record of the heartbeat is called
• An ECG or EKG
• What two electrical events are being recorded?
• Depolarization and repolarization
Answer the following questions
26
27. Chapter 12| cardiovascular practice
• What does the P wave represent?
• Atrial depolarization
• What does the QRS complex represent?
• Ventricular deplarization
• What does the QRS complex over shadow?
• Atrial repolarization
• What does the T wave represent?
• Ventricular replarization
Answer the following questions
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28. Chapter 12 |Blood Vessels
• Types of blood vessels
• Arteries
• Carry blood Away from heart
• Capillaries
• Exchange of nutrients and gasses
• Veins
• Carry blood toward heart
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30. Chapter 12 | blood vessels
• Structure of blood vessels
• Veins
• One-way valves
• Capillaries
• Microscopic
• Tunica intima is only layer
• Endothelial cells
• Ease of passage in/out of glucose,
oxygen, wastes
• Precapillary sphincters
• Regulate blood flow through capillary
bed
• Thoroughfare channel
• Main channel through capillary bed
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31. Chapter 12 | blood vessels
• Functions of blood vessels
• Arteries
• Blood from _______________ to ______________
• Constrict and dilate to maintain arterial BP
• Veins
• Blood from ________________ to _____________
• Reservoir; expand or contract
• Capillaries
• Blood from ________________ to _____________
• Exchange of nutrients, gasses, and fluid
31
34. Chapter 12| cardiovascular practice
• What are the two main types of blood vessels in the body?
• Arteries and veins
• Which vessel transports oxygenated blood?
• arteries
• Where does the exchange of nutrients, gasses, and liquids occur?
• Capillaries
• What type of muscle controls blood flow to the capillary beds?
• Precapillary sphincters
Answer the following questions
34
35. Chapter 12| cardiovascular practice
• Name the wall layers of arteries and veins.
• Tunica externa
• Tunica media
• Tunica intima
• Which layer contains smooth muscle?
• Tunica media
• What controls the tension of the smooth muscle?
• By the autonomic nervous system
• Which vessel is used as a reservoir for blood?
• Veins
Answer the following questions
35
36. Chapter 12 | Circulation of Blood
• Systemic circulation of blood
• From left ventricle of heart
• Oxygenated blood through aorta
• To body
• Back to right atrium of heart
• Deoxygenated blood through
superior & inferior vena cava
• Pulmonary circulation of blood
• From right ventricle of heart
• To lungs
• Back to left atrium of heart
• Oxygenated blood through four pulmonary veins
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37. Chapter 12 | Circulation of Blood
• Hepatic portal circulation
• Digestive capillary bed veins from
• spleen, stomach, pancreas, gallbladder, and intestines
• Mesenteric vein → hepatic portal vein
• Funneled through liver capillary bed
• Nutrient rich blood processed
• Excess glucose stored as glycogen
• Removal of toxins
• Blood returned to inferior vena cava
Hepatic refers to the liver
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38. Chapter 12| cardiovascular practice
• Why does blood from the intestines need to pass through the
liver before circulating through the body?
• The blood is nutrient rich – it is very high in glucose and other substances
• What does the liver do to the glucose from digestion?
• Converts glucose to glycogen for storage
Answer the following questions
38
39. Chapter 12| cardiovascular practice
• What is the name of the vein that leads into the liver?
• Hepatic portal vein
• To what vessel does the liver return the nutrient filtered blood?
• Inferior vena cava
Answer the following questions
39
40. Chapter 12 | Blood Pressure
• Defining blood pressure
• Push of blood
• Exists in all blood vessels
• BP gradient
• Difference between:
• Aorta (highest BP)
• Venae cavae (lowest BP)
• Indicates blood flow
40
41. Chapter 12 | Blood Pressure
• Defining blood pressure
• Hypertension (HTN)
• Rupture of blood vessels
• Hypotension
• Perfusion of vital organs lacking
• Hemorrhage
• Pronounced loss of blood
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43. Chapter 12 | Blood Pressure
• Factors influencing blood pressure
• Blood volume
• ↑volume = ↑ BP
• ↓ volume = ↓ BP
• Hemorrhage (loss of blood)
• Diuretics (↑ urine output)
• Strength of heart contractions
• ↑ contraction strength = ↑ blood pumped
• 70 mL pumped into aorta with each contraction (stroke volume)
• 70 bpm
• 70mL x 70 bpm = 4900 mL (almost 5 liters of blood through aorta every minute)
43
44. Chapter 12 | Blood Pressure
• Factors influencing blood pressure
• Heart rate
• ↑rate = ↑ BP
• Blood viscosity (thickness)
• ↑ viscosity = ↑ BP
• Resistance to blood flow
• Blood vessel walls – local adjustments effect entire system
• Peripheral resistance; any force that acts against the flow of blood through vessel
• Anything that slows blood, such as ↑ viscosity
• Vasomotor mechanism; smooth muscle tension adjustment to control BP
• Vasoconstriction, vasodilation
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45. Chapter 12 | Blood Pressure
• Fluctuations in blood pressure
• Normal BP is LESS THAN 120/80
• 120 mmHg systolic pressure 80 mmHg diastolic pressure
• Central venous pressure
• Venous BP in right atrium
• Mechanisms that keep venous blood moving
1. Continuous heart beat
2. Arterial BP is adequate
3. Valves in the veins (semilunar)
4. Skeletal muscle contraction
5. Breathing creates a pump in the thorax
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48. Chapter 12| cardiovascular practice
• The BP gradient is the difference between ______ and ______.
• Highest and lowest blood pressures
• Where is BP the highest? Where is BP the lowest?
• Aorta is highest Vena cava is lowest
• What effect does increased blood volume have on BP?
• Increased volume = increased BP
• What effect would a decreased strength of heart contraction have on BP?
• Decreases BP
Answer the following questions
48
49. Chapter 12| cardiovascular practice
• What does viscosity of blood refer to?
• The thickness of the blood
• How many factors that resist (slow down) blood flow can you think of?
• ↑ viscosity
• Diameter of blood vessel (smooth muscle contraction/relaxation)
• What is the vasomotor mechanism?
• The vasodilation (expansion) and vasoconstriction (reduction) of blood vessels
at a local site.
Answer the following questions
49
50. Chapter 12| cardiovascular practice
• What is considered normal blood pressure?
• Less than 120 mmHg / 80 mmHg
• Systolic/diastolic is the pressure during ventricular contraction.
• systolic
• What is the name of the pressure during ventricular relaxation?
• diastole
• The pressure of blood in the right atrium is called _______.
• Central venous pressure
Answer the following questions
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51. Chapter 12| cardiovascular practice
• What mechanisms assist arterial blood flow (3)?
• Heart contraction
• Arterial walls – muscular and elastic
• Gravity
• What mechanisms assist venous blood return (5)? (CAVSB)
• Continued heart beat
• Arterial BP adequate
• Valves
• Skeletal muscle contraction
• Breathing
Answer the following questions
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52. References
Bitterjug, (2012). Figure walking and speaking through megaphone [Image]. Retrieved from
https://openclipart.org/detail/169403/announcing
Chabner, D. E. (2014). The language of medicine, 10th ed. St Louis, MO: Elsevier Saunders.
Patton, K. T. (2013). Anatomy and physiology (8th ed.). St. Louis, MO: Elsevier Mosby.
Smiley faces [Image]. (n.d.). Creative commons. Retrieved from images.google.com.
Thibodeau, G. A. & Patton, K. T. (2012). Structure and function of the body (14th ed.). St.
Louis, MO: Elsevier Mosby.
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